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Heat Shock Protein-Based Therapies, Alexzander A.A. Asea; Naif N. Almasoud; Sunil Kris


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Автор: Alexzander A.A. Asea; Naif N. Almasoud; Sunil Kris
Название:  Heat Shock Protein-Based Therapies
ISBN: 9783319172101
Издательство: Springer
Классификация:




ISBN-10: 3319172107
Обложка/Формат: Hardcover
Страницы: 385
Вес: 0.77 кг.
Дата издания: 04.08.2015
Серия: Heat Shock Proteins
Язык: English
Издание: 1st ed. 2015
Иллюстрации: 20 tables, black and white; 23 illustrations, color; 28 illustrations, black and white; xvi, 385 p. 51 illus., 23 illus. in color.
Размер: 234 x 156 x 24
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine general
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

Contents

Contributors
Preface

SECTION I: HEAT SHOCK PROTEIN HSP27-BASED THERAPIES
1 HSP27 as a Therapeutic Target of Novel Inhibitors and Dietary Phytochemicals in Cancer
Elena Arechaga-Ocampo and Cйsar Lуpez-Camarillo
2 Heat Shock Protein 27 (HSP27, HSPB1) is Up-Regulated by Targeted Agents and Confers Resistance to Both Targeted Drugs and Chemotherapeutics
Daniele Musiani, John D. Konda, Simona Pavan, Erica Torchiaro, Jessica Erriquez, Martina Olivero and Maria F. Di Renzo

3 Heat Shock Proteins and Cancer: Plant Based Therapy
Evren Цnay-Ucar

SECTION II: HEAT SHOCK PROTEIN HSP60-BASED THERAPIES
4 Chaperonotherapy for Alzheimers Disease: Focusing on HSP60
Francesco Cappello, Antonella M. Gammazza, Silvia Vilasi, Maria G. Ortore, Pier L. San-Biagio, Claudia Campanella, Andrea Pace, Antonio P. Piccionello, Giulio Taglialatela, Everly C. De Macario and Alberto J. l. Macario

5 Secreted and Circulating Cell Stress Proteins in the Periodontal Diseases
Brian Henderson, Nikos Donos, Luigi Nibali and Frank Kaiser

SECTION III: HEAT SHOCK PROTEIN HSP70-BASED THERAPIES

6 The Role of Heat Shock Protein 70 in Infection and Immunity
Jose Rey-Ladino, Abiola Senok, Abdullah Sarkar and Ahlam Al Shedoukhy

7 Potential Cytoprotective Effects of Heat Shock Proteins to Skeletal Muscle
John P. Vardiman, Philip M. Gallagher and Jacob A. Siedlik

8 Heat Shock Proteins in Triple-Negative Breast Cancer (TNBC) TreatmentPunit Kaurunit Kaur, Tarundeep arundeep Singh, Moses Galukandealukande, Sunil Krishnanrishnan and Alexzander A. A. Asealexzander Asea

9 Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe?
Rosaria Tinnirello, Giuseppina Turturici, Gabriella Sconzo, Walter Spinello, Alexzander A. A. Asea and Fabiana Geraci

10 New Indications for HSP90 and HSP70 Inhibitors as Antiviral Drugs
Matthew K. Howe and Timothy A. J. Haystead

11 Potential Applications of Nanoparticles for Hyperthermia
Caio C. Quini and Sunil Krishnan

SECTION IV: HEAT SHOCK PROTEIN HSP90-BASED THERAPIES

12 Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer Treatment
Susanta S. Adhikari, Sujan K. Mondal and Rajkumar Banerjee

13 Potential of HSP90 Inhibitors to Treat Neurofibromatosis-Related Tumors
Jeremie Vitte and Marco Giovannini

14 Role of Heat Shock Protein 90 in the Cause of Various Diseases: A Potential Therapeutic Target
Subhankar Paul

15 HSP90 Inhibitor-Based Strategies for Cancer Therapy: Advancing Toward Clinical Impact
David A. Proia and Richard C. Bates

16 Molecular Survival Strategies of Organisms: HSP and Small Molecules for Diagnostics and Drug Development
Andreas Kirschning, Johanna-Gabriela Walter, Frank Stahl, Emilia Schax, Thomas Scheper, Pooyan Aliuos and Carsten Zeilinger
17 Targeting Heat Shock Proteins in Colorectal Cancer
Sheah L. Lee, Nina C. Dempsey-Hibbert, Dale Vimalachandran, Terence D. Wardle, Paul Sutton and John H. H. Williams

Index




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Автор: Richard R Burgess
Название: Guide to Protein Purification,436
ISBN: 0123749786 ISBN-13(EAN): 9780123749789
Издательство: Elsevier Science
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Описание: Examines some of the most reliable, robust methods for researchers in biochemistry, molecular and cell biology, genetics, pharmacology and biotechnology. This book relates how these traditional methods connect to the explosive advancements in the field. It includes chapters on both common and less-common relevant techniques.

Molecular Therapies of Cancer

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ISBN: 3319132776 ISBN-13(EAN): 9783319132778
Издательство: Springer
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Описание: Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.

Heat Shock Protein Inhibitors

Автор: McAlpine
Название: Heat Shock Protein Inhibitors
ISBN: 3319326058 ISBN-13(EAN): 9783319326054
Издательство: Springer
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Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Heat Shock Proteins and Whole Body Adaptation to Extreme Environments

Автор: Michael B. Evgen`ev; David G. Garbuz; Olga G. Zats
Название: Heat Shock Proteins and Whole Body Adaptation to Extreme Environments
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Издательство: Springer
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Описание: For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

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Название: Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection
ISBN: 9048178134 ISBN-13(EAN): 9789048178131
Издательство: Springer
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Цена: 32004.00 р.
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ISBN: 9400758324 ISBN-13(EAN): 9789400758322
Издательство: Springer
Рейтинг:
Цена: 26552.00 р.
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Описание: This book presents the research evidence relevant to the application of a range of commonly used non-pharmacological interventions in supportive cancer care, including massage, acupressure, Qigong, yoga, mind-body therapy, and mindfulness-based intervention.

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Автор: Stephan A. Sieber
Название: Activity-Based Protein Profiling
ISBN: 3642448313 ISBN-13(EAN): 9783642448317
Издательство: Springer
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Цена: 36570.00 р.
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Описание: SieberActivity-Based Protein Profiling for Natural Product Target Discovery, by Joanna Krysiak und Rolf BreinbauerPhotoaffinity Labeling in Activity-Based Protein Profiling, by Paul P. TateFunctional Analysis of Protein Targets by Metabolomic Approaches, by Yun-Gon Kim und Alan Saghatelian

Protein-Based Photovoltaics

Название: Protein-Based Photovoltaics
ISBN: 1498724892 ISBN-13(EAN): 9781498724890
Издательство: Taylor&Francis
Рейтинг:
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Описание: Photosynthetic protein complexes have an overall quantum yield close to 100%. Photovoltaic devices using protein complexes can provide an economical alternative to existing solar cells. This book explains how to build and improve the efficiency of protein solar energy conversion devices.


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