Assessing Rare Variation in Complex Traits, Eleftheria Zeggini; Andrew Morris

Автор: Anna K. Naumova; Celia M.T. Greenwood
Название: Epigenetics and Complex Traits
ISBN: 1461480779 ISBN-13(EAN): 9781461480778
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book covers basic epigenetic phenomena; interplay of epigenetic and genetic factors; the influences of epigenetic factors on inheritance; relationships between epigenetic and genetic changes in human disease and statistical analysis of epigenetic effects.

Автор: Jerome Morio
Название: Estimation of Rare Event Probabilities In Complex Aerospace And O
ISBN: 008100091X ISBN-13(EAN): 9780081000915
Издательство: Elsevier Science
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Цена: 24423.00 р.
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Описание:

Rare event probability (10^-4 and less) estimation has become a large area of research in the reliability engineering and system safety domains. A significant number of methods have been proposed to reduce the computation burden for the estimation of rare events from advanced sampling approaches to extreme value theory. However, it is often difficult in practice to determine which algorithm is the most adapted to a given problem. Estimation of Rare Event Probabilities in Complex Aerospace and Other Systems: A Practical Approach provides a broad up-to-date view of the current available techniques to estimate rare event probabilities described with a unified notation, a mathematical pseudocode to ease their potential implementation and finally a large spectrum of simulation results on academic and realistic use cases.

Автор: Jose C. Florez
Название: The Genetics of Type 2 Diabetes and Related Traits
ISBN: 3319015737 ISBN-13(EAN): 9783319015736
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Covering the very latest advanced insights into type-2 diabetes arising from the rapid developments in human genetics, this volume covers all aspects of the topic, from genetic discovery to interpretation of genetic findings and clinical applications.

Автор: Rongling Wu; Changxing Ma; George Casella
Название: Statistical Genetics of Quantitative Traits
ISBN: 1441919120 ISBN-13(EAN): 9781441919120
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Aimed at graduate students and researchers and including statistical models and analytical procedures, this book introduces the basic concepts and methods used in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture and related fields.