Описание: This book reviews diversity-oriented synthesis (DOS), a leading and dynamic area in organic chemistry and drug discovery. It first covers key chemical methods for the generation of small molecules according to DOS principles as well as important classes of molecules generated through DOS approaches.
Автор: Dobson, C.M. (Inorganic Chemistry Laboratory, Univ Название: Foundations of Chemical Biology ISBN: 0199248990 ISBN-13(EAN): 9780199248995 Издательство: Oxford Academ Рейтинг: Цена: 4434.00 р. Наличие на складе: Поставка под заказ.
Описание: Introduces the fundamental chemistry of the molecules that are essential to all cells. Covering biological chemistry from a chemical viewpoint, this book integrates mechanistic chemistry and physical chemical principles. Specific examples are included, in order that the students see the scientific principles 'in action'.
Автор: Philip J. Snodgrass Название: Chemical Probes in Biology ISBN: 1461347793 ISBN-13(EAN): 9781461347798 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research.
Автор: Volker A. Erdmann; Wojciech T. Markiewicz; Jan Bar Название: Chemical Biology of Nucleic Acids ISBN: 3642544517 ISBN-13(EAN): 9783642544514 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future research.
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