The Role of Microenvironment in the Control of Tumor Angiogenesis, Domenico Ribatti

Автор: Gianfranco Baronzio; Giammaria Fiorentini; Christo
Название: Cancer Microenvironment and Therapeutic Implications
ISBN: 1402095759 ISBN-13(EAN): 9781402095757
Издательство: Springer
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Цена: 23508.00 р.
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Описание: Explores cancer micro environments and host interactions. This book is suitable for clinical oncologists, clinical hematologists, research oncologists, research hematologists, immunologists, stem cell researchers, oncology and hematology fellows (trainees).

Автор: Andrei Thomas-Tikhonenko
Название: Cancer Genome and Tumor Microenvironment
ISBN: 1461425247 ISBN-13(EAN): 9781461425243
Издательство: Springer
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Цена: 36570.00 р.
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Описание: There exists a large body of evidence suggesting that well-known mutations in cancer genes profoundly affect tumor milieu. The reviews in this book explore in detail how tumor microenvironment and progression are "hard-wired" at the genetic level.

Автор: Rebecca G. Bagley
Название: The Tumor Microenvironment
ISBN: 146142660X ISBN-13(EAN): 9781461426608
Издательство: Springer
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Цена: 36570.00 р.
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Описание: This book explores the many biological and physical aspects of the tumor microenvironment. It represents a superb compilation of the latest thoughts and data on this topic, and the in-depth chapters are written by known professionals in the field.

Автор: Yefenof
Название: Innate and Adaptive Immunity in the Tumor Microenvironment
ISBN: 9048177138 ISBN-13(EAN): 9789048177134
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host.

Автор: Aref
Название: Ex Vivo Engineering of the Tumor Microenvironment
ISBN: 3319453955 ISBN-13(EAN): 9783319453958
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

Автор: Rejniak
Название: Systems Biology of Tumor Microenvironment
ISBN: 3319420216 ISBN-13(EAN): 9783319420219
Издательство: Springer
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Цена: 22203.00 р.
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Описание: This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology.

Автор: Ursini-Siegel
Название: The Tumor Microenvironment
ISBN: 1493937995 ISBN-13(EAN): 9781493937998
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This book covers core and emerging in vitro and in vivo protocols used to study how various components of the tumor microenvironment are established and subsequently interact with tumor cells to facilitate carcinogenesis. In addition, the book examines research topics including cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies to target the microenvironment, and, finally, advanced techniques in the fields of tissue engineering and nanotechnology. Written and validated in the laboratories of a number of trusted collaborating authors for the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Koumenis
Название: Tumor Microenvironment
ISBN: 3319266640 ISBN-13(EAN): 9783319266640
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology (e.g., HIF regulation) and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery; and critically evaluate novel targets for imaging or therapeutic intervention that would be of use to the tumor microenvironment community and pharmaceutical industry.

Автор: Constantinos Koumenis; Ester Hammond; Amato Giacci
Название: Tumor Microenvironment and Cellular Stress
ISBN: 1461459141 ISBN-13(EAN): 9781461459149
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Constitutes proceeding that discusses different cellular and animal models of TME study and identifies common pathways that are candidates for therapeutic intervention, stimulate collaboration between groups that are focused on elucidation of biochemical aspects of stress biology and groups that study pathophysiological aspects of stress pathways.

Автор: Baronzio
Название: Cancer Microenvironment and Therapeutic Implications
ISBN: 9048181607 ISBN-13(EAN): 9789048181605
Издательство: Springer
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Цена: 20896.00 р.
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Описание: This book examines cancer microenvironments and host interactions with an eye towards exploiting our understanding for new treatments. The team of contributors share amongst them impressive experiences at the laboratory bench and in the clinic.