Hemostasis and Thrombosis, Emmanuel J. Favaloro; Giuseppe Lippi

Part I: Introductory Chapters

1. Overview of Hemostasis and Thrombosis and Contribution of Laboratory Testing to Diagnosis and Management of Hemostasis and Thrombosis Disorders

Roslyn A. Bonar, Giuseppe Lippi, and Emmanuel J. Favaloro

2. Preanalytical Issues in Hemostasis and Thrombosis Testing

Giuseppe Lippi and Emmanuel J. Favaloro

3. The Interface between Immunotransfusion and Hemostasis and Thrombosis Testing

Massimo Franchini

Part II: Routine Coagulation Assays

4. Optimizing the Verification of Mean Normal Prothrombin Time (MNPT) and International Sensitivity Index (ISI) for Accurate Conversion of Prothrombin Time (PT) to International Normalized Ratio (INR)

Emmanuel J. Favaloro

Geoffrey Kershaw

6. Performance and Interpretation of Mixing Tests in Coagulation

Geoffrey Kershaw

7. D-Dimer Testing: Laboratory Aspects and Current Issues

Jecko Thachil, Giuseppe Lippi, and Emmanuel J. Favaloro

8. Determination of Fibrinogen and Thrombin Time (TT)

Anetta Undas

Part III: Thrombophilia-Related Chapters

9. An Overview of Thrombophilia and Associated Laboratory Testing

Martina Montagnana, Giuseppe Lippi, and Elisa Danese

10. Laboratory Testing for Activated Protein C Resistance (APCR)

11. Assessment of Hereditary Thrombophilia: Performance of Protein C (PC) Testing

Richard A. Marlar and Jana N. Gausman

12. Assessment of Hereditary Thrombophilia: Performance of Protein S (PS) Testing

Richard A. Marlar and Jana N. Gausman

13. Assessment of Hereditary Thrombophilia: Performance of Antithrombin (AT) Testing

Jana N. Gausman and Richard A. Marlar

14. Lupus Anticoagulant Testing: Diluted Russell Viper Venom Time (dRVVT)

Vittorio Pengo, Elisa Bison, Alessandra Banzato, Giacomo Zoppellaro, Seena Padayattil Jose, and Gentian Denas

15. Lupus Anticoagulant Testing: Activated Partial Thromboplastin Time (APTT) and Silica Clotting Time (SCT)

Armando Tripodi and Veena Chantarangkul

16. Solid Phase Immunoassay for the Detection of Anticardiolipin Antibodies

Rohan Willis, Elizabeth Papalardo, and E. Nigel Harris

17. Solid Phase Immunoassay for the Detection of Anti-β2 Glycoprotein I Antibodies

Rohan Willis, Elizabeth Papalardo, and E. Nigel Harris

18. Measuring Direct Oral Anticoagulants

19. Laboratory Testing Protocols for Heparin-Induced Thrombocytopenia (HIT) Testing

Kun Kan Edwin Lau, Soma Mohammed, Leonardo Pasalic, and Emmanuel J. Favaloro

Part IV: Bleeding Disorders

20. One-Stage Factor VIII Assays

Elizabeth Duncan and Susan Rodgers

21. Chromogenic Factor VIII Assays for Improved Diagnosis of Hemophilia A

Susan Rodgers and Elizabeth Duncan

22. Assessment of Factor XIII