DNA and Histone Methylation as Cancer Targets, Atsushi Kaneda; Yu-ichi Tsukada

Автор: Chatterjee
Название: Molecular Targets and Strategies in Cancer Prevention
ISBN: 3319312529 ISBN-13(EAN): 9783319312521
Издательство: Springer
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Цена: 22359.00 р.
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Описание: The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are highlighted to provide a means and design of future cancer prevention strategies and challenges thereupon. The volume also explores various receptor drugs that are in development process with the emphasis of inhibitors used to prevent malignant gene expression. The book bridges the gap between basic science and clinical application of current knowledge of cancer and emphasizes that tumor progression and cancer metastasis are not random - treatments and cure are logical and eventual.

Автор: Moshe Szyf
Название: DNA Methylation and Cancer Therapy
ISBN: 1441934162 ISBN-13(EAN): 9781441934161
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Once techniques to probe the methylation profile of whole genomes as well as specific genes became available, it became clear that DNA methylation patterns are gene and tissue specific and that patterns of gene expression correlate with patterns of methylation.

Автор: P.A. Jones; P.K. Vogt
Название: DNA Methylation and Cancer
ISBN: 3642640907 ISBN-13(EAN): 9783642640902
Издательство: Springer
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Цена: 16979.00 р.
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Описание: This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer.

Автор: Manel Esteller
Название: DNA Methylation, Epigenetics and Metastasis
ISBN: 9048169178 ISBN-13(EAN): 9789048169177
Издательство: Springer
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Цена: 34799.00 р.
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Автор: Eric Verdin
Название: Histone Deacetylases
ISBN: 1617376027 ISBN-13(EAN): 9781617376023
Издательство: Springer
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Цена: 34799.00 р.
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Описание: A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression.

Автор: Shelley L. Berger; O. Nakanishi; Bernhard Haendler
Название: The Histone Code and Beyond
ISBN: 364242175X ISBN-13(EAN): 9783642421754
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin.

Автор: Tso-Pang Yao; Edward Seto
Название: Histone Deacetylases: the Biology and Clinical Implication
ISBN: 3642270859 ISBN-13(EAN): 9783642270857
Издательство: Springer
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Цена: 41925.00 р.
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Описание: The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Автор: Siddik
Название: Checkpoint Controls and Targets in Cancer Therapy
ISBN: 1617796352 ISBN-13(EAN): 9781617796357
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Checkpoint regulation is critical in understanding cancer development and cancer therapy. This book builds upon existing concepts of checkpoints and aims to expand our understanding of the inner workings of the critical checkpoint machinery.