Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity, Akihiko Yoshimura

Автор: Andras Perl (Editor)
Название: Autoimmunity: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1607617196 ISBN-13(EAN): 9781607617198
Издательство: Springer
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Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.

Автор: Val?rie Quesniaux; Bernhard Ryffel; Franco Di Pado
Название: IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
ISBN: 3034807732 ISBN-13(EAN): 9783034807739
Издательство: Springer
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Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.

Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti
Название: The Impact of Biotechnology on Autoimmunity
ISBN: 9401044848 ISBN-13(EAN): 9789401044844
Издательство: Springer
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Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.

Автор: Willis X. Li
Название: Cell Cycle Checkpoints
ISBN: 1493961810 ISBN-13(EAN): 9781493961818
Издательство: Springer
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Описание:

1. Studying G2 DNA Damage Checkpoints using the Fission Yeast Schizosaccharomyces pombe

Nicolas Rhind

2. Studying S-phase DNA Damage Checkpoints using the Fission Yeast Schizosaccharomyces pombe

Nicolas Rhind

3. Methods for Studying the G2 DNA Damage Checkpoint in Mammalian Cells

Claudia Tapia-Alveal and Matthew J. O'Connell

4. Evaluating Spindle Assembly Checkpoint Competence in Mouse Oocytes using Immunoblotting

Hayden Homer

5. Analysis of Changes in Protein Level and Subcellular Localization during Cell Cycle Progression using the Budding Yeast Saccharomyces cerevisiae

Xiaorong Wu, Lili Liu, and Mingxia Huang

6. Studying Cell Cycle Checkpoints using Drosophila Cultured Cells

Katarzyna Siudeja, Jannie de Jong, and Ody C. M. Sibon

7. In Vivo Live-Analysis of Cell Cycle Checkpoints in Drosophila Early Embryos

Saeko Takada and Byeong J. Cha

8. Using Drosophila Larval Imaginal Discs to Study Low Dose Radiation-induced Cell Cycle Arrest

Shian-Jang Yan and Willis X. Li

9. Screening for Radiation Sensitizers of Drosophila Checkpoint Mutants

Mara Gladstone and Tin Tin Su

10. Study of Cell Cycle Checkpoints using Xenopus Cell-free Extracts

Seetha V. Srinivasan and Jean Gautier

11. Analyzing DNA Replication Dynamics of Genotoxin-Treated Cells Using Velocity Sedimentation

Tovah A. Day, Chris Sproul, Marila Cordeiro-Stone, and Cyrus Vaziri

12. Methods For Studying Checkpoint Kinases - Chk1

Claudia Tapia-Alveal and Matthew J. O'Connell

13. A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases

Bunsyo Shiotani and Lee Zou

14. Analyzing p53 regulated DNA Damage Checkpoints by Flow Cytometry

Lois Resnick-Silverman and James J. Manfredi

15. Using Drosophila S2 Cells to Measure S phase-Coupled Protein Destruction via Flow Cytometric Analysis

Jean M. Davidson and Robert J. Duronio

16. Assessing G1-to-S-phase Progression After Genotoxic Stress

Michael DeRan, Mary Pulvino, and Jiyong Zhao

17. Indirect Immunofluorescence for Monitoring Spindle Assembly and Disassembly in Yeast

Jacob W. P. Keeling and Rita K. Miller

18. Detecting Recruitment of DNA Damage Response Factors through the eChIP Approach

Yucai Wang and Lei Li

19. Methods to Study Cancer Therapeutic Drugs that Target Cell Cycle Checkpoints

Yun Dai and Steven Grant

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Автор: Andreas Radbruch; Peter E. Lipsky
Название: Current Concepts in Autoimmunity and Chronic Inflammation
ISBN: 364206745X ISBN-13(EAN): 9783642067457
Издательство: Springer
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Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.

Автор: Andras Perl
Название: Autoimmunity
ISBN: 149395637X ISBN-13(EAN): 9781493956371
Издательство: Springer
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Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.

Автор: Moncef Zouali
Название: Molecular Autoimmunity
ISBN: 1461498945 ISBN-13(EAN): 9781461498940
Издательство: Springer
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Описание: - Preface -Contributors -Innate Immunity in Experimental Autoimmune Myocarditis -Toll-Like Receptor 9 and Autoimmunity -C-Reactive Protein as a Regulator of Autoimmune Disease -NKT Cells and Autoimmune Type 1 Diabetes -The Genetics of Human Autoimmune Diseases -Failure to Maintain T cell DNA Methylation and Chromatin Structure Contributes to Human Lupus -Complement Components C4A and C4B in Human Lupus -Non-MHC Genetic Polymorphisms with Functional Importance for Human Myasthenia Gravis -Rheumatic Heart Disease: Molecular Basis of Autoimmune Reactions Leading to Valvular Lesions -Autoimmunity Against Desmogleins in Pemphigus Vulgaris -The Molecular Basis of Celiac Disease -Intrathymic Expression of Neuromuscular Acetylcholine Receptors and the Immunopathogenesis of Myasthenia Gravis -Autoantiboties and Nephritis: Different Roads May Lead to Rome -Estrogen, Interferon-gamma, and Lupus -Extent of Regulatory T cell Influence on Major Histocompatibility Complex Class II Gene Control of Susceptibility in Murine Autoimmune Thyroiditis -The Role of Autoimmunity in Multiple Sclerosis -Crippled B Lymphocyte Signaling Checkpoints in Systemic Autoimmunity -Disrupted T cell Receptor Signaling Pathways in Systemic Autoimmunity -Immune cell Signaling and Gene Transcription in Human Systemic Lupus Erythematosus -Accumulation of Self-Antigens in Systemic Lupus Erythematosus -B Lymphocyte Depletion Therapy in Autoimmune Disorders: Chasing Trojan Horse? -B Lymphocyte Stimulator (BLyS) and Autoimmune Rheumatic Diseases -Control and Induction of Autoimmunity by Cytokine and Anti-Cytokine Treatments -Hematopoietic Stem Cell Transplantation for the Treatment of Severe Autoimmune Diseases -Molecular Mimicry in Autoimmune Uveitis: From Pathogenesis to Therapy -Molecular Pathogenesis of the Antiphospholipid Syndrome: Towards Novel Therapeutic Targets -A Novel Approach to the Prevention of Atherosclerosis -Antigen-SpecificRegulation of Autoimmunity -Index

Автор: Ekkehard K.F. Bautz; Joachim R. Kalden; Mitsuo Hom
Название: Molecular and Cell Biology of Autoantibodies and Autoimmunity. Abstracts
ISBN: 3540514368 ISBN-13(EAN): 9783540514367
Издательство: Springer
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Автор: Nathanson
Название: Viral Pathogenesis and Autoimmunity.2002
ISBN: 0781711037 ISBN-13(EAN): 9780781711036
Издательство: Lippincott Williams & Wilkins
Цена: 8237.00 р.
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Описание: Written by eminent authorities on viral pathogenesis and immunity, this text provides a coherent, concise introduction to the field. The authors focus on fundamental principles and present a well-organized overview that is easy for readers to absorb.Section 1, essentials of viral pathogenesis , describes the sequential events in viral infection, the localization of viral infections, and the variety of virus-cell interactions.Section 2, host responses to viral infection , examines immune responses, including virus-induced immunopathology and immunosuppression.Section 3, virus-host interactions , covers virulence, viral persistence, virus-induced oncogenesis, and host susceptibility.Section 4, prevention of viral infections , explains the key principles of vaccine development.

Автор: Moncef Zouali
Название: Autoimmunity: Experimental Aspects
ISBN: 3642787819 ISBN-13(EAN): 9783642787812
Издательство: Springer
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Описание: Proceedings of the NATO Advanced Research Workshop on Fundamental and Experimental Aspects of Autoimmunity, held at Acquafredda di Maratea, Italy, May 22 - 26, 1993

Автор: A. Pinchera
Название: Thyroid Autoimmunity
ISBN: 1461282586 ISBN-13(EAN): 9781461282587
Издательство: Springer
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Описание: In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes.