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Molecular Mechanisms of Microbial Evolution, Pabulo H. Rampelotto


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Цена: 30745.00р.
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Автор: Pabulo H. Rampelotto
Название:  Molecular Mechanisms of Microbial Evolution
ISBN: 9783319690773
Издательство: Springer
Классификация:



ISBN-10: 3319690779
Обложка/Формат: Hardcover
Вес: 1.06 кг.
Дата издания: 23.10.2018
Серия: Grand Challenges in Biology and Biotechnology
Язык: English
Издание: 1st ed. 2018
Иллюстрации: 80 tables, color; 54 illustrations, color; 17 illustrations, black and white; xiii, 448 p. 71 illus., 54 illus. in color.
Размер: 241 x 188 x 28
Читательская аудитория: General (us: trade)
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:
One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms. Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis.
Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health.
Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.

Дополнительное описание: tba



Molecular Biology and Genomics,

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
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Цена: 6772.00 р.
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Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

Fundamentals of Molecular Evolution.2ed

Автор: Graur
Название: Fundamentals of Molecular Evolution.2ed
ISBN: 0878932666 ISBN-13(EAN): 9780878932665
Издательство: Oxford Academ
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Цена: 22650.00 р.
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Описание: This textbook has been updated to incorporate the many advances in genomics, protein engineering, computational biology and bioinformatics. In the 2nd edition, the authors continue to explain evolutionary change at the molecular level in a way that can be understood without much prerequisite knowledge of molecular biology, evolution or mathematics.

Essential Molecular Biology V1

Автор: Brown
Название: Essential Molecular Biology V1
ISBN: 0199636427 ISBN-13(EAN): 9780199636426
Издательство: Oxford Academ
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Цена: 9425.00 р. 13464.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: This text is a guide to the basic techniques needed for molecular biology. It concentrates on the preparation, purification and handling of nucleic acids.

Molecular Biology  Principles of Genome Function

Автор: Craig Nancy
Название: Molecular Biology Principles of Genome Function
ISBN: 0199658579 ISBN-13(EAN): 9780199658572
Издательство: Oxford Academ
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Цена: 9186.00 р.
Наличие на складе: Поставка под заказ.

Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.

Molecular Mechanisms of Microbial Adhesion

Автор: Lech Switalski; Magnus H??k; Edwin Beachey
Название: Molecular Mechanisms of Microbial Adhesion
ISBN: 1461281695 ISBN-13(EAN): 9781461281696
Издательство: Springer
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Цена: 14673.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists.

Microbial Metabolic Engineering (Methods in Molecular Biology 834)

Автор: Cheng (Ed)
Название: Microbial Metabolic Engineering (Methods in Molecular Biology 834)
ISBN: 1617794821 ISBN-13(EAN): 9781617794827
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Metabolic engineering is the practice of genetically optimizing metabolic and regulatory networks within cells to increase production and/or recovery of certain substance from cells. In Microbial Metabolic Engineering: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study metabolic engineering. These include methods and techniques to engineer genes and pathways, use of modern biotechnology tools in microbial metabolic engineering, and examples of metabolic engineering for real world applications such as whole cell biosensors and acetate control in large scale fermentation. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microbial Metabolic Engineering: Methods and Protocols seeks to provide researchers with an overview of key topics on microbial metabolic engineering.

Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)

Название: Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)
ISBN: 9812386149 ISBN-13(EAN): 9789812386144
Издательство: World Scientific Publishing
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Цена: 13622.00 р.
Наличие на складе: Поставка под заказ.

Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct.

The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.

Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction

Автор: Friedrich Marks, Ursula Klingmuller, Karin Muller- Decker
Название: Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction
ISBN: 0815345348 ISBN-13(EAN): 9780815345343
Издательство: Taylor&Francis
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Цена: 11023.00 р.
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Описание:

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.


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