Описание: Each year hundreds of new drugs are approved for the marketplace. The approval of a single new drug is the result of years of screening tens of thousands of compounds, performing pre-clinical research on their effects, and designing, implementing, and analyzing the results of clinical trials. This book provides a general guide to statistical methods used in the pharmaceutical industry, and is aimed at graduate students and researchers who want to know more about statistical applications in all phases of the drug development process. The 19 chapters authored by over 30 statisticians working in the industry follow the general sequence of drug development, from pre-clinical research and saftey assessment to dose finding, safety studies, large clinical trials, analysis of health economic data, and fianlly manufacturing and production. Special topics such as single patient analysis and the impact of patient compliance show the broad spectrum of applications of data analysis methods. Each chapter illustrates a practical problem using data from actual studies by describing the study, the data, the methods, and the results. All of the analyses are done with S-PLUS, and the data and code are provided both in appendices to the chapters and on the companion Springer-Verlag web site, making it possible to reproduce the results and extend the analyses. Prior knowledge of the software is not required to follow the analyses. Steven P. Millard is a statistical consultant and also Manager of Consulting Services for MathSoft, Inc. (Data Analysis Products Division.) He has applied statistical methods to projects ranging from quality control in bioassay to measuring water quality to automating home appraisal, and has taught courses in S-PLUS for over 10 years. He is the author of the book Environmental Statistics with S-PLUS (CRC Press) as well as the S-PLUS add-in module ENVIRONMENTALSTATS for S-PLUS. Andreas Krause is a statistical consultant in the pharmaceutical industry and works for Novartis Pharma AG. He has extensive experience in graphical and numerical data analysis as well as programming, has taught numerous classes with and on S-PLUS, and is an S_PLUS user from the early days on. He is also author of the book The Basics of S and S-PLUS (Springer).
Автор: Ettore Lanzarone; Francesca Ieva Название: The Contribution of Young Researchers to Bayesian Statistics ISBN: 3319020838 ISBN-13(EAN): 9783319020839 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first Bayesian Young Statisticians Meeting, BAYSM 2013, has provided a unique opportunity for young researchers, M.S.
Автор: Fulvia Mecatti; Pier Luigi Conti; Maria Giovanna R Название: Contributions to Sampling Statistics ISBN: 331935857X ISBN-13(EAN): 9783319358574 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: it deals with some hot topics in sampling theory, such as calibration, quantile-regression and multiple frame surveys and with innovative methodologies in important topics of both sampling theory and applications.
Автор: Kei Takeuchi Название: Contributions to Mathematical Statistics ISBN: 4431552383 ISBN-13(EAN): 9784431552383 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is a reorganized edition of Kei Takeuchi`s works on various problems in mathematical statistics based on papers and monographs written since the 1960s on several topics in mathematical statistics and published in various journals in English and in Japanese.
Автор: H. Schneeweiss; H. Strecker Название: Contributions to Econometrics and Statistics Today ISBN: 3642701914 ISBN-13(EAN): 9783642701917 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Leon J. Gleser; Michael D. Perlman; S. James Press Название: Contributions to Probability and Statistics ISBN: 1461282004 ISBN-13(EAN): 9781461282006 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Published in honor of the sixty-fifth birthday of Professor Ingram Olkin of Stanford University. The volume reflects the wide range of Professor Olkin`s interests in and contributions to research in statistics, and provides an overview of new developments in these areas of research.
Автор: Ingo Klein; Stefan Mittnik Название: Contributions to Modern Econometrics ISBN: 1441953310 ISBN-13(EAN): 9781441953315 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of econometrics has gone through remarkable changes during the last thirty-five years. This development becomes apparent when looking at the biography of an econometrician whose illustrious research and teaching career started about thirty-five years ago and who will retire very soon after his 65th birthday.
Автор: Sendler Название: Contributions to Stochastics ISBN: 3642468950 ISBN-13(EAN): 9783642468957 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the contributions to this volume stem from very different fields, no attempt was made to find a systematic ordering. All results are new in so far as they have not been published so far.
Автор: B. Raj; J. Koerts Название: Henri Theil`s Contributions to Economics and Econometrics ISBN: 9401050635 ISBN-13(EAN): 9789401050630 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PREFACE TO THE COLLECTION PREAMBLE The editors are pleased to present a selection of Henri Theil`s contributions to economics and econometrics in three volumes.
Автор: B. Raj; J. Koerts Название: Henri Theil`s Contributions to Economics and Econometrics ISBN: 9401051240 ISBN-13(EAN): 9789401051248 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PREFACE TO THE COLLECTION PREAMBLE The editors are pleased to present a selection of Henri Theil`s contributions to economics and econometrics in three volumes.
Автор: Paula Brito; Patrice Bertrand; Guy Cucumel; Franci Название: Selected Contributions in Data Analysis and Classification ISBN: 3540735585 ISBN-13(EAN): 9783540735588 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents methodological developments in data analysis and classification. This work covers topics including, methods for classification and clustering, dissimilarity analysis, graph analysis, consensus methods, conceptual analysis of data, analysis of symbolic data, data mining, and knowledge discovery in databases.
Автор: B. Raj; J. Koerts Название: Henri Theil`s Contributions to Economics and Econometrics ISBN: 9401050627 ISBN-13(EAN): 9789401050623 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PREFACE TO THE COLLECTION PREAMBLE The editors are pleased to present a selection of Henri Theil`s contributions to economics and econometrics in three volumes.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
