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Phagocytosis of Dying Cells, Dmitri V. Krysko; Peter Vandenabeele


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Автор: Dmitri V. Krysko; Peter Vandenabeele
Название:  Phagocytosis of Dying Cells
ISBN: 9789401782999
Издательство: Springer
Классификация:



ISBN-10: 9401782997
Обложка/Формат: Paperback
Страницы: 447
Вес: 0.64 кг.
Дата издания: 12.09.2014
Язык: English
Издание: 2009 ed.
Иллюстрации: X, 447 p.
Размер: 234 x 156 x 24
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: From Molecular Mechanisms to Human Diseases
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Phagocytosis has been at the forefront of cell biology for more than a century. Initially, phagocytosis, which comes from Greek words meaning “devouring cells,” was discovered in the late 19th century by Ilya Metchnikoff, who was awarded, together with Paul Ehrlich, the Nobel Prize in Physiology and Medicine in 1908 “in recognition of their work on immunity.” At that time Metchnikoff had already identified a function for phagocytes not only in host defense but also as scavengers of degenerating host cells during metamorphosis of tadpoles, thus providing one of the first descriptions of apoptotic cell clearance by macrophages (Kaufmann 2008). Since then, much has been learned about phagocytosis, and the previous several decades have witnessed outstanding progress in understanding the functions and the molecular mechanisms of phagocytosis. Two main types of targets are cleared by phagocytosis: microbial pathogens and dying cells. Rapid recognition and clearance of dying cells by phagocytes plays a pivotal role in development, maintenance of tissue homeostasis, control of immune responses, and resolution of inflammation. Clearance of dying cells can be divided into several stages, including sensing, r- ognition, binding and signaling, internalization, and immunological responses. In this book, our contributors address these different stages of dead cell cle- ance and examine how impaired clearance of dying cells may lead to human d- eases. We have attempted to provide sufficient cross-referencing and indexing to enable the reader to easily locate the ideas elaborated in the different chapters.
Дополнительное описание: Molecular Mechanisms of Phagocytosis of Dying Cells.- Molecular Pathways of Different Types of Cell Death: Many Roads to Death.- Apoptotic, Autophagic and Necrotic Cell Death Types in Pathophysiological Conditions: Morphological and Histological Aspects.-



Phagocytosis of dying cells

Автор: Dmitri V. Krysko; Peter Vandenabeele (Eds.)
Название: Phagocytosis of dying cells
ISBN: 140209292X ISBN-13(EAN): 9781402092923
Издательство: Springer
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Цена: 29209.00 р.
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Описание: Deals with the advances made in uncovering the molecular and cellular basis of phagocytosis of apoptotic and necrotic dying cells. This book examines the possibility of using apoptotic cells in the prevention and treatment of graft rejection and in the rational design of immunotherapy and vaccines for cancer treatment.

Phagocytosis and Phagosomes

Автор: Roberto Botelho
Название: Phagocytosis and Phagosomes
ISBN: 1493965794 ISBN-13(EAN): 9781493965793
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume details experimental approaches used to investigate phagocytosis and phagosome maturation. Chapters present methods and protocols on quantifying uptake and phagosome maturation using biophysical and biochemical approaches, proteomics, microscopy, and flow cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Phagocytosis and Phagosomes: Methods and Protocols aims to be an important resource for both experts in the field and for those investigators delving into phagocytosis and phagosome maturation for the first time.

Molecular Mechanisms of Phagocytosis

Автор: Carlos Rosales
Название: Molecular Mechanisms of Phagocytosis
ISBN: 1489997636 ISBN-13(EAN): 9781489997630
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function.


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