Mitochondrial Regulation, Carlos M. Palmeira; Anabela P. Rolo

Автор: Gvozdjakova
Название: Mitochondrial Medicine
ISBN: 1402067135 ISBN-13(EAN): 9781402067136
Издательство: Springer
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Описание: Mitochondrial Medicine is an area where several disciplines from basic science to clinical medicine converge. Based upon data gathered over 30 years of clinical and experimental research, this book features internationally recognized authors who share their experience in various fields such as mitochondrial cardiology, neurology, and diabetology.

Автор: Orrenius
Название: Mitochondrial Signaling in Health and Disease
ISBN: 1439880026 ISBN-13(EAN): 9781439880029
Издательство: Taylor&Francis
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Описание:

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.

Автор: Carlos M. Palmeira; Anabela P. Rolo
Название: Mitochondrial Regulation
ISBN: 1493946129 ISBN-13(EAN): 9781493946129
Издательство: Springer
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Описание:

1. Isolation of Crud Mitochondrial Fraction from Cells

Mariusz R. Wieckowski and Lech Wojtczak

2. Isolation of Mitochondria from Liver and Extraction of Total RNA and Protein - Analyses of MicroRNA and Protein Expressions

Pedro M. Borralho, Clifford J. Steer, and Cecнlia M. P. Rodrigues

3. PCR Based Determination of Mitochondrial DNA Copy Number in Multiple Species

Rooney JP, Ryde IT, Sanders LH, Howlett EH, Colton MD, Germ KE, Mayer GD, Greenamyre JT, and Meyer JN

4. NAD⁺ Content and its Role in Mitochondria

Wei Li and Anthony A. Sauve

5. Measuring PGC-1α and its Acetylation Status in Mouse Primary Myotubes

Ana P. Gomes and David A. Sinclair

6. Measurement of Mitochondrial Oxygen Consumption Rates in Mouse Primary Neurons and Astrocytes

Sofia M. Ribeiro, Alfredo Gimйnez-Cassina, and Nika N. Danial

7. Determination Of Oxidative Phosphorylation Complexes Activities

Joгo S. Teodoro, Carlos M. Palmeira, and Anabela P. Rolo

8. Histoenzymatic Methods for Visualization of the Activity of Individual Mitochondrial Respiratory Chain Complexes in the Muscle Biopsies from Patients with Mitochondrial Defects

Agnieszka Karkucinska-Wieckowska, Maciej Pronicki, and Mariusz R. Wieckowski

9. A Method Aimed at Assessing the Functional Consequences of the Supramolecular Organization of the Respiratory Electron Transfer Chain by Time-resolved Studies

Fabrice Rappaport

10. BN-PAGE-based Approach to Study Thyroid Hormones and Mitochondrial Function

Elena Silvestri, Assunta Lombardi, Federica Cioffi, and Fernando Goglia

11. Detection of UCP1 Protein and Measurements of Dependent GDP-Sensitive Proton Leak in Non-Phosphorylating Thymus Mitochondria

Kieran J. Clarke, Audrey M. Carroll, Gemma O'Brien & Richard K. Porter

12. Exploring Liver Mitochondrial Function By ¹³c-Stable Isotope Breath Tests. Implications In Clinical Biochemistry

Ignazio Grattagliano, Leonilde Bonfrate, Michele Lorusso, Luigi Castorani, Ornella de Bari, and Piero Portincasa

13. Following Mitochondria Dynamism: Confocal Analysis of The Organelle Morphology

F. R. Mariotti, M. Corrado, and S. Campello

Автор: F.N. Gellerich; S. Zierz
Название: Detection of Mitochondrial Diseases
ISBN: 1461378001 ISBN-13(EAN): 9781461378006
Издательство: Springer
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Автор: Paul R. Sanberg; Hitoo Nishino; Cesario V. Borlong
Название: Mitochondrial Inhibitors and Neurodegenerative Disorders
ISBN: 1468498215 ISBN-13(EAN): 9781468498219
Издательство: Springer
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Описание: Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a symbiotic relationship in which it dutifully served as the efficient source of A TP for cell function.

Автор: Valentin Luzikov
Название: Mitochondrial Biogenesis and Breakdown
ISBN: 1468416529 ISBN-13(EAN): 9781468416527
Издательство: Springer
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Описание: It is a strange fact that many modern cell biochemists have a keen interest in biosynthetic processes, such as protein and nucleic biosynthesis or organelle biogenesis, but tend to regard degradative processes merely as irritating reactions that disrupt the flow of synthetic reactions. Historically, the elucidation of catabolic pathways preceded that of anabolic pathways, so that there is also a tendency to regard work on proteases, phospholipases, nucleases, etc., as somewhat "old-fashioned. " It is the great contribution of Professor Luzikov's book to show that, at least in the case of mito- chondrial research, the separation of studies on anabolic and cata- bolic processes has been very harmful. In an extremely erudite and measured way, the author carefully develops the argument that we can only understand mitochondrial biogenesis fully if we take into account the role of degradative processes. The action of lytic enzymes is shown not to be a random affair, but rather a process that is fully integrated into the process of mitochondrial assembly. A second important contribution of this book is the fact that it contains a masterly review of the fundamental literature on mitochon- drial structure, function, breakdown and synthesis presented in an integrated and logical manner.

Автор: Michael Forte; Marco Colombini
Название: Molecular Biology of Mitochondrial Transport Systems
ISBN: 3642789382 ISBN-13(EAN): 9783642789380
Издательство: Springer
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Описание: Proceedings of the NATO Advanced Research Workshop on Molecular Biology of Mitochondrial Transport Systems, held at Il Ciocco, Italy, September 17 - 21, 1992

Автор: Angelo Azzi; Katarzyna A. Nalecz; Maciej J. Nalecz
Название: Anion Carriers of Mitochondrial Membranes
ISBN: 3642745415 ISBN-13(EAN): 9783642745416
Издательство: Springer
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Описание: All relevant structural and functional aspects of the Anion Carriers of Mitochondrial Membranes as well as isolation procedures, reconstitution experiments and biogenesis of the carriers, kinetics of transport as well as the metabolic regulation mechanisms are treated in this volume.

Автор: Hong Kyu Lee; Salvatore DiMauro; Masashi Tanaka; Y
Название: Mitochondrial Pathogenesis
ISBN: 1573314919 ISBN-13(EAN): 9781573314916
Издательство: Springer
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Автор: Paul R. Sanberg; Hitoo Nishino; Cesario V. Borlong
Название: Mitochondrial Inhibitors and Neurodegenerative Disorders
ISBN: 089603805X ISBN-13(EAN): 9780896038059
Издательство: Springer
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Описание: Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a symbiotic relationship in which it dutifully served as the efficient source of A TP for cell function.

Автор: J.J. Lemasters; C.R. Hackenbrock; R.G. Thurman; H.
Название: Integration of Mitochondrial Function
ISBN: 0306429993 ISBN-13(EAN): 9780306429996
Издательство: Springer
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Описание: In aerobic tissues such as heart, brain, kidney, liver and brown fat, mitochon- dria account for more than 20% of cell protein and play an essential role in res- piration, ATP formation, ketogenesis, gluconeogenesis, amino acid metabolism, ureagenesis, thermogenesis and a variety of other metabolic activities. The mecha- nisms by which these activities are integrated and regulated within the overall context of cellular physiology is of much current research interest. In order to bring together scientists examining the various diverse aspects of this overall pro- blem, an International Conference on INTEGRATION OF MITOCHONDRIAL FUNC- TION was held June 4-7, 1987 at the Hanes Art Center on the campus of the Uni- versity of North Carolina at Chapel Hill. The chapters of this volume derive from presentations made at this conference. The focus of INTEGRATION OF MITOCHONDRIAL FUNCTION is on signifi- cant new experimental and theoretical advances concerning integration of mito- chondrial function at the organelle, cell, tissue and whole organism levels of organization.