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Systems Biology of Apoptosis, Inna N. Lavrik


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Автор: Inna N. Lavrik
Название:  Systems Biology of Apoptosis
ISBN: 9781489993120
Издательство: Springer
Классификация:



ISBN-10: 1489993126
Обложка/Формат: Paperback
Страницы: 204
Вес: 0.31 кг.
Дата издания: 15.10.2014
Язык: English
Размер: 234 x 156 x 12
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book details the contemporary systems biology studies devoted to apoptotic signaling and examines how systems biology helps to understand life/death decisions made in the cell as well as helps to develop new approaches to rational treatment strategies.


Apoptosis: The Molecular Biology of Programmed Cell Death

Название: Apoptosis: The Molecular Biology of Programmed Cell Death
ISBN: 0199638497 ISBN-13(EAN): 9780199638499
Издательство: Oxford Academ
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Цена: 14256.00 р.
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Описание: This work is intended for postgraduate students in cell biology, postdoctoral researchers new to the field, advanced undergraduates, postgraduate medical students, and clinicians undertaking research training in the area.

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

Автор: Gregory
Название: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
ISBN: 3319394045 ISBN-13(EAN): 9783319394046
Издательство: Springer
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Цена: 23757.00 р.
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Описание:

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Application of Apoptosis to Cancer Treatment

Автор: Mels Sluyser
Название: Application of Apoptosis to Cancer Treatment
ISBN: 9048168333 ISBN-13(EAN): 9789048168330
Издательство: Springer
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Цена: 26552.00 р.
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Описание: Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body.

Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells

Автор: Iman Tavassoly
Название: Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells
ISBN: 331914961X ISBN-13(EAN): 9783319149615
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.

Apoptosis Methods in Toxicology

Автор: Perpetua M. Muganda
Название: Apoptosis Methods in Toxicology
ISBN: 1493935860 ISBN-13(EAN): 9781493935864
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This detailed volume provides a single, valuable reference source formethods that definitively identify and accurately quantify apoptosis. Itcontinues with multi-parametric and phased apoptosis assays for detecting earlyand late apoptosis or distinguishing apoptosis from necrosis and autophagy.

Apoptosis and Cancer

Автор: Gil Mor; Ayesha B. Alvero
Название: Apoptosis and Cancer
ISBN: 149395525X ISBN-13(EAN): 9781493955251
Издательство: Springer
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Цена: 13275.00 р.
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Описание:

1. Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-induced Apoptosis

Gaurav S. Choudhary, Sayer Al-harbi, and Alexandru Almasan

2. Flow Cytometry Enumeration Of Apoptotic Cancer Cells By Apoptotic Rate

David Diaz, Alfredo Prieto, Eduardo Reyes, Hugo Barcenilla, Jorge Monserrat, and Melchor Alvarez-Mon

3. "Multiplexed Viability, Cytotoxicity, and Caspase Activity Assays"

Andrew L. Niles and Terry L. Riss

4. A Multiplexed Method for Kinetic Measurements of Apoptosis and Proliferation using Live Content Imaging

Katherine Artymovich and Daniel M. Appledorn

5. Detection of End Stage Apoptosis by ApopTag(R) TUNEL Technique

Chandra Mohan, Kevin Long, Manpreet Mutneja, and Jun Ma

6. Detection and Quantification of Apoptosis in Primary Cells using Taqman(R) Protein Assay

Christina Pfister, Heike Pfrommer, Marcos S. Tatagiba, and Florian Roser

7. Detection of p53 Protein Aggregation in Cancer Cell Lines and Tumor Samples

Yang Yang-Hartwich, Jamie Bingham, Francesca Garofalo, Ayesha B. Alvero, and Gil Mor

8. Detection of p53 Protein Transcriptional Activity by Chromatin Immunoprecipitation

Yang Yang-Hartwich, Emily Romanoff, Jamie Bingham, Ayesha B. Alvero, and Gil Mor

9. Homogeneous, Bioluminescent Proteasome Assays

Martha A. O'Brien, Richard A. Moravec, Terry L. Riss, and Robert F. Bulleit

10. Laser Capture Microdissection for Gene Expression Analysis

Mallikarjun Bidarimath, Andrew K. Edwards, and Chandrakant Tayade

11. Using the Peggy Simple Western System for Fine Needle Aspirate Analysis

Erik T. Gentalen and John M. Proctor

12. Analysis of Autophagosome Formation Using Lentiviral Biosensors for Live Fluorescent Cellular Imaging

Kevin Long, Chandra Mohan, Janet Anderl, Karyn Huryn-Selvar, Haizhen Liu, Kevin Su, Mark Santos, Matthew Hsu, Lucas Armstrong, and Jun Ma

13. Optical Imaging of Ovarian Cancer Using HER-2 Affibody Conjugated Nanoparticles

Minati Satpathy, Rafal Zielinski, Ilya Lyakhov, and Lily Yang

14. Measuring Cardiac Autophagic Flux in vitro and in vivo

Michael A. Gurney, Chengqun Huang, Jennifer M. Ramil, Nandini Ravindran, Allen M. Andres, Jon Sin, Phyllis-Jean Linton, and Roberta A. Gottlieb

15. PET Imaging for Tyrosine Kinase Inhibitor (TKI) Biodistribution in Mice

Hiroshi Fushiki, Yoshihiro Murakami, Sosuke Miyoshi, and Shintaro Nishimura

Essentials of Apoptosis

Автор: Xiao-Ming Yin; Zheng Dong
Название: Essentials of Apoptosis
ISBN: 1493956493 ISBN-13(EAN): 9781493956494
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.

Apoptosis and Its Modulation by Drugs

Автор: Ross G. Cameron; George Feuer
Название: Apoptosis and Its Modulation by Drugs
ISBN: 3540661212 ISBN-13(EAN): 9783540661214
Издательство: Springer
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Цена: 58774.00 р.
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Описание: with contributions by numerous experts

Apoptosis, Cell Signaling, and Human Diseases

Автор: Rakesh Srivastava
Название: Apoptosis, Cell Signaling, and Human Diseases
ISBN: 1617377139 ISBN-13(EAN): 9781617377136
Издательство: Springer
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Цена: 22201.00 р.
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Описание: These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways.

Apoptosis, Cell Signaling, and Human Diseases

Автор: Rakesh Srivastava
Название: Apoptosis, Cell Signaling, and Human Diseases
ISBN: 1617378232 ISBN-13(EAN): 9781617378232
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer.

Apoptosis Techniques and Protocols

Автор: Andr?a C. LeBlanc
Название: Apoptosis Techniques and Protocols
ISBN: 1617373060 ISBN-13(EAN): 9781617373060
Издательство: Springer
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Цена: 20263.00 р.
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Apoptosis

Автор: Y. Kuchino; W.E.G. M?ller
Название: Apoptosis
ISBN: 3642798527 ISBN-13(EAN): 9783642798528
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Apoptosis plays a central role in the regulation of cell proliferation. Disruption of this control mechanism may cause serious human diseases such as encephalomyelitis and cancer. Thus, understanding of the molecular mechanisms of apoptotic cell death should lead to fundamental advances in the therapy of these diseases.


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