New Challenges for Cancer Systems Biomedicine, Alberto D`Onofrio; Paola Cerrai; Alberto Gandolfi
Автор: Quarteroni Название: Complex Systems in Biomedicine ISBN: 8847003946 ISBN-13(EAN): 9788847003941 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Поставка под заказ.
Описание: Mathematical modeling of human physiopathology is a tremendously ambitious task. It encompasses the modeling of most diverse compartments such as the cardiovascular, respiratory, skeletal and nervous systems, as well as the mechanical and biochemical interaction between blood flow and arterial walls, or electrocardiac processes and the electric conduction into biological tissues. Mathematical models can be set up to simulate both vasculogenesis (the aggregation and organisation of endothelial cells dispersed in a given environment) and angiogenesis (the formation of new vessels sprouting from an existing vessel) that are relevant to the formation of vascular networks, and in particular to the description of tumor growth. The integration of models aimed at simulating the cooperation and interrelation of different systems is an even more difficult task. It calls for the set up of, for instance, interaction models for the integrated cardio-vascular system and the interplay between central circulation and peripheral compartments, models for the mid-long range cardiovascular adjustments to pathological conditions (e.g. to account for surgical interventions, congenital malformations, or tumor growth), models for the integration among circulation, tissue perfusion, biochemical and thermal regulation, models for parameter identification and sensitivity analysis to parameter changes or data uncertainty – and many others. The heart is a complex system in itself, where electrical phenomena are functionally related with the wall deformation. In its turn, electrical activity is related with heart physiology. It involves nonlinear reaction-diffusion processes and provides the activation stimulus to the heart dynamics and eventually the blood ventricular flow that drives the haemodynamics of the whole circulatory system. In fact, the influence is reciprocal, since the circulatory system in turns affects the heart dynamics and may induce an overload depending upon the individual physiopathologies ( for instance the presence of a stenotic artery or a vascular prosthesis).Virtually, all the fields of mathematics have a role to play in this context. Geometry and approximation theory provide the tools for handling clinical data acquired by tomography or magnetic resonance, identifying meaningful geometrical patterns and producing three-dimensional geometrical models stemming from the original patients data. Mathematical analysis, flow and solid dynamics, stochastic analysis are used to set up the differential models and predict uncertainty. Numerical analysis and high performance computing are needed to numerically solve the complex differential models. Finally, methods from stochastic and statistical analysis are exploited for the modeling and interpretation of space-time patterns. Indeed, the complexity of the problems at hand often stimulates the use of innovative mathematical techniques that are able, for instance, to accurately catch those processes that occur at multiple scales in time and space (like cellular and systemic effects), and that are governed by heterogeneous physical laws.
Автор: C. Fotakis; T.G. Papazoglou; C. Kalpouzos Название: Optics and Lasers in Biomedicine and Culture ISBN: 3642630731 ISBN-13(EAN): 9783642630736 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The contributors to this volume cover such international research activities as photon migration in tissue, fibre optics, lasers in dermatology, ENT, cardiology, and in art conservation, imaging techniques in archaeology, laser technologies in contemporary art, and new laser and opto-electronic systems for biomedical and art-related studies.
Описание: This book describes current research on disease biomarkers, including oncofetal molecules in cancer prediction and treatment, evolving development in cancer biology at the cellular and molecular levels and understanding of new classes of molecules in diseases.
Автор: Santiago Ib??ez; Jes?s S. P?rez del R?o; Antonio P Название: Progress and Challenges in Dynamical Systems ISBN: 3662510499 ISBN-13(EAN): 9783662510490 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book contains papers based on talks given at the International Conference Dynamical Systems: 100 years after Poincare held at the University of Oviedo, Gijon in Spain, September 2012.
Описание: This edited volume contains a selection of chapters that are an outgrowth of the - ropean Conference on Mathematical and Theoretical Biology (ECMTB05, Dresden, Germany, July 2005). The peer-reviewed contributions show that mathematical and computational approaches are absolutely essential for solving central problems in the life sciences, ranging from the organizational level of individual cells to the dynamics of whole populations. The contributions indicate that theoretical and mathematical biology is a diverse and interdisciplinary ?eld, ranging from experimental research linked to mathema- cal modeling to the development of more abstract mathematical frameworks in which observations about the real world can be interpreted, and with which new hypotheses for testing can be generated. Today, much attention is also paid to the development of ef?cient algorithms for complex computation and visualisation, notably in molecular biology and genetics. The ?eld of theoretical and mathematical biology and medicine has profound connections to many current problems of great relevance to society. The medical, industrial, and social interests in its development are in fact indisputable.
Автор: Panos Pardalos; Vladimir L. Boginski; Alkis Vazaco Название: Data Mining in Biomedicine ISBN: 1441943439 ISBN-13(EAN): 9781441943439 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.
Автор: Aickin Название: Causal Analysis in Biomedicine and Epidemiology ISBN: 0824707486 ISBN-13(EAN): 9780824707484 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "Provides current models, tools, and examples for the formulation and evaluation of scientific hypotheses in causal terms. Introduces a new method of model parametritization. Illustrates structural equations and graphical elements for complex causal systems."
Автор: Fr?d?ric Cazals; Pierre Kornprobst; Oliver Faugera Название: Modeling in Computational Biology and Biomedicine ISBN: 3642446698 ISBN-13(EAN): 9783642446696 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes synergy between technological advances and input from physics, chemistry, mathematics, statistics and computer science. Surveys progress in bioinformatics, biomedicine and neuroscience, and highlights outstanding theoretical questions.
Автор: Y. Cherruault Название: Mathematical Modelling in Biomedicine ISBN: 9027721491 ISBN-13(EAN): 9789027721495 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; the Minkowsky lemma, cod- ing theory and the structure of water meet one another in packing and covering theory;
Автор: Allan L. Goldstein Название: Frontiers in Biomedicine ISBN: 1461368936 ISBN-13(EAN): 9781461368939 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The lectures, approximately one hour in length, were broadcast live from The George Washington University Medical Center in Washington, D. In partnership with Medical Consumer Media, the lectures were simultaneously broadcast live around the world via the Internet with real-time audio streaming and digitized 35mm slide presentation.
Описание: Challenges in Design and Implementation of Middlewares for Real-Time Systems brings together in one place important contributions and up-to-date research results in this fast moving area.
Автор: Santiago Ib??ez; Jes?s S. P?rez del R?o; Antonio P Название: Progress and Challenges in Dynamical Systems ISBN: 3642388299 ISBN-13(EAN): 9783642388293 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book contains papers based on talks given at the International Conference Dynamical Systems: 100 years after Poincare held at the University of Oviedo, Gijon in Spain, September 2012.
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