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Regulation of Gene Expression, Gary H. Perdew; Jack P. Vanden Heuvel; Jeffrey M.


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Автор: Gary H. Perdew; Jack P. Vanden Heuvel; Jeffrey M.
Название:  Regulation of Gene Expression
ISBN: 9781627038089
Издательство: Springer
Классификация:


ISBN-10: 1627038086
Обложка/Формат: Paperback
Страницы: 333
Вес: 0.48 кг.
Дата издания: 22.11.2014
Язык: English
Издание: 2007 ed.
Иллюстрации: Ix, 333 p.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.
Дополнительное описание: Gene Expression Control At The Mrna Level.- Overview.- Messenger RNA Accumulation.- Transcript Profiling.- Transcriptional Regulation of Gene Expression.- Posttranscriptional Processing of Messenger RNA.- Regulation Of Protein Levels And Transcription Fac



NTC`s Dictionary of Everyday American English Expression

Название: NTC`s Dictionary of Everyday American English Expression
ISBN: 0844257796 ISBN-13(EAN): 9780844257792
Издательство: McGraw-Hill
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Цена: 4117.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Containing more than 7,000 phrases, this dictionary covers situations from talking to a doctor to ordering a meal, and helps learners communicate personal feelings, and make small talk.

Regulation of Gene Expression in the Tumor Environment

Автор: Menashe Bar-Eli
Название: Regulation of Gene Expression in the Tumor Environment
ISBN: 1402083408 ISBN-13(EAN): 9781402083402
Издательство: Springer
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Цена: 32004.00 р.
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Описание: The development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. This book discusses different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype.

Regulation of Gene Expression by Hormones

Автор: Kenneth McKerns
Название: Regulation of Gene Expression by Hormones
ISBN: 1468444204 ISBN-13(EAN): 9781468444209
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Among our interests are global resource management, human reproduction, hormonal regulation of normal and cancer cells, study of aging and degenerative diseases, brain peptides, peptide neurotransmitter compounds, mechanism of action of hormones, peptide hormone synthesis, and recombinant DNA techniques.

Regulation of Gene Expression in the Tumor Environment

Автор: Menashe Bar-Eli
Название: Regulation of Gene Expression in the Tumor Environment
ISBN: 9048178495 ISBN-13(EAN): 9789048178490
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This volume examines several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype, shedding further light on the understanding of these complicated processes.

Coordinated Regulation of Gene Expression

Автор: R. Clayton
Название: Coordinated Regulation of Gene Expression
ISBN: 1461293154 ISBN-13(EAN): 9781461293156
Издательство: Springer
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Цена: 12157.00 р.
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Regulation of Gene Expression in Animal Viruses

Автор: Luis Carrasco; Nahum Sonenberg; Eckard Wimmer
Название: Regulation of Gene Expression in Animal Viruses
ISBN: 1461362717 ISBN-13(EAN): 9781461362715
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ASI held in Mallorca, Spain, May 30-June 8, 1992

Regulation of Gene Expression and Brain Function

Автор: Paul J. Harrison; Paul J. Harrison; M. Morrison-Bo
Название: Regulation of Gene Expression and Brain Function
ISBN: 3540571566 ISBN-13(EAN): 9783540571568
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Gene expression converts the information coded by our genesinto proteins. This volume presents a didacticapproach to the understanding of the basic processes of geneexpression and their involvement in certain brain diseases,such asAlzheimer`s disease and schizophrenia.

Translational Regulation of Gene Expression

Автор: J. Ilan
Название: Translational Regulation of Gene Expression
ISBN: 146845367X ISBN-13(EAN): 9781468453676
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Given the accelerated growth of knowledge in the field of gene expression, it seemed timely to discuss current developments in the area of translational reg- ulation of gene expression as well as to evaluate emerging technology. Translational regulation occurs with prokaryotic as well as with eukaryotic messenger RNA (mRNA) in vivo and in vitro. In prokaryotes, through genetic manipulations and mutagenesis, the mechanisms are much better understood, as for example the mechanism of attenuation. In bacteria, different translational efficiencies for the same mRNA may vary by lOOO-fold. Translational regulation was first observed in 1966 with RNA phages of Escherichia coli by Lodish and Zinder. However, translational regulation of proteins from DNA genomes is also well described for bacteria, as for example gene 32 protein of bacteriophage T4 and E. coli ribosomal proteins. In eukaryotes, the utilization of an individual mRNA species with different efficiencies is poorly understood. For example, mRNA for ribosomal proteins is translationally regulated during Drosophila oogenesis, without any clue to the mechanism involved. It was observed that ribosomal protein mRNA during Drosophila oogenesis and embryogenesis is selectively on or off the polysomes during different developmental stages. In contrast, bacterial ribosomal protein is also translationally regulated by autogenous regulation. The mechanism is well understood and involves binding of the gene product to its transcript in competition with rRNA.

Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation

Автор: Wajapeyee
Название: Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation
ISBN: 1493965166 ISBN-13(EAN): 9781493965168
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume describes a variety of protocols that will allow the readers to study different aspects of transcriptional and posttranscriptional gene expression regulation in eukaryotic cells. Chapters focus on the latest use of CRISPRi and RNAi technologies for studying various aspects of transcriptional and posttranscriptional regulation and tools to navigate protocols on key bioinformatics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfallsAuthoritative and cutting-edge, Eukaryotic Transcription and Post-Transcription Gene Expression Regulation aims to ensure successful results in the further study of this vital field.

Developmental Regulation of Plant Gene Expression

Автор: Don Grierson
Название: Developmental Regulation of Plant Gene Expression
ISBN: 940105357X ISBN-13(EAN): 9789401053570
Издательство: Springer
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Цена: 11179.00 р.
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Описание: The intricacies of plant growth and development present a fascinating intellectual challenge, and yet our understanding of the subject has increased relatively slowly, despite the application of many different experimental approaches.

Regulation of Immune Gene Expression

Автор: Marc Feldmann; Andrew McMichael
Название: Regulation of Immune Gene Expression
ISBN: 0896031047 ISBN-13(EAN): 9780896031043
Издательство: Springer
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Цена: 32004.00 р.
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Описание: The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, or MHC Class II antigens.

Regulation of Cytokine Gene Expression in Immunity and Diseases

Автор: Ma
Название: Regulation of Cytokine Gene Expression in Immunity and Diseases
ISBN: 940240919X ISBN-13(EAN): 9789402409192
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.


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