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Biomedical Informatics for Cancer Research, Michael F. Ochs; John T. Casagrande; Ramana V. Dav


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Автор: Michael F. Ochs; John T. Casagrande; Ramana V. Dav
Название:  Biomedical Informatics for Cancer Research
ISBN: 9781489984517
Издательство: Springer
Классификация:



ISBN-10: 1489984518
Обложка/Формат: Paperback
Страницы: 354
Вес: 0.52 кг.
Дата издания: 26.11.2014
Язык: English
Издание: 2010 ed.
Иллюстрации: Xviii, 354 p.
Размер: 234 x 156 x 20
Читательская аудитория: Professional & vocational
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant proteins, since any tre- ment must aim to improve health to justify its potential side effects. Treatment for cancer must become highly individualized, focusing on the specific aberrant driver proteins in an individual. This drives a need for informatics in cancer far beyond the need in other diseases. For instance, routine treatment with statins has become widespread for minimizing heart disease, with most patients responding to standard doses (Wilt et al. 2004). In contrast, standard treatment for cancer must become tailored to the molecular phenotype of an individual tumor, with each patient receiving a different combination of therapeutics aimed at the specific aberrant proteins driving the cancer. Tracking the aberrations that drive cancers, identifying biomarkers unique to each individual for molecular-level di- nosis and treatment response, monitoring adverse events and complex dosing schedules, and providing annotated molecular data for ongoing research to improve treatments comprise a major biomedical informatics need.
Дополнительное описание: Concepts, Issues, and Approaches.- Biomedical Informatics for Cancer Research: Introduction.- Clinical Research Systems and Integration with Medical Systems.- Data Management, Databases, and Warehousing.- Middleware Architecture Approaches for Collaborati



Principles of Biomedical Informatics, 2 ed

Автор: Kalet Ira J.
Название: Principles of Biomedical Informatics, 2 ed
ISBN: 0124160190 ISBN-13(EAN): 9780124160194
Издательство: Elsevier Science
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Цена: 12462.00 р.
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Описание: Provides a treatment of the deep computational ideas at the foundation of the field. This book includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: tree structured data, interval trees, and time-oriented medical data and their use.

Designing clinical research

Автор: Hulley
Название: Designing clinical research
ISBN: 1608318044 ISBN-13(EAN): 9781608318049
Издательство: Lippincott Williams & Wilkins
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Цена: 12355.00 р.
Наличие на складе: Поставка под заказ.

Описание: Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in every chapter, with new material on: • non-inferiority trials for comparative effectiveness research • incidence-density case-control studies • confounding and effect modification • diagnostic test studies to inform prediction rules • ethical aspects of whole genome sequencing • automated data management approaches • new NIH grant-writing requirements Color format, and Electronic access, powered by Inkling™ as a free companion to the text • viewable through your browser or as a download to tablet or smartphone • the complete text with optimized navigation • note-sharing, highlighting and bookmarking capability • cross-linking of references and content • rapid search options linked to the new glossary

Biomedical Research

Автор: Rutkove, S. B.
Название: Biomedical Research
ISBN: 1493936530 ISBN-13(EAN): 9781493936533
Издательство: Springer
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Цена: 10480.00 р.
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Описание: This comprehensive yet concise book introduces people at all levels of training—undergraduate, graduate, and medical students, residents, fellows, and junior faculty—to the basic joys and challenges of biomedical research. By discussing many key research issues, would-be and early-stage academics will not only be better informed about the world of biomedical research, but will learn a basic set of instructions to help jumpstart their careers. Biomedical Research: An Insider’s Guide is divided into five sections. The first focuses on decision points regarding whether or not to enter research and if so what type: basic, clinical, or translational. The second section focuses on the practicalities of pursuing medical research, including institutional review boards and animal care committees as well general suggestions regarding idea generation and collaboration. The third section covers a core aspect of research: writing—detailing the evolution of both grants and papers. The fourth section addresses a range of issues, including conferencing to patents to working with industry to obtaining philanthropic support. The final section deals with all-important broader life issues from job choices to being a mentor to thoughts on how to keep the big picture front and center. An invaluable resource that offers insightful, practical advice, Biomedical Research: An Insider’s Guide reveals how biomedical research can be both challenging and truly rewarding.

Pediatric Biomedical Informatics

Автор: John J. Hutton
Название: Pediatric Biomedical Informatics
ISBN: 9401782202 ISBN-13(EAN): 9789401782203
Издательство: Springer
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Цена: 29209.00 р.
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Описание: This book introduces informatics resources that can accelerate the transfer of information from bench to bedside. Furthermore, it addresses special challenges posed by support of clinical and basic research involving children and their families.

International Conference on Biomedical and Health Informatics

Автор: Yuan-Ting Zhang; Paulo Carvalho; Ratko Magjarevic
Название: International Conference on Biomedical and Health Informatics
ISBN: 9811045046 ISBN-13(EAN): 9789811045042
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume presents the proceedings of the International Conference on Biomedical and Health Informatics (ICBHI). The conference was a new special topic conference and a common initiative by the International Federation of Medical and Biological Engineering (IFMBE) and IEEE Engineering in Medicine and Biology Society (IEEE- EMBS). BHI2015 was held in Haikou, China, 8-10 October 2015. The main theme of the BHI2015 is "The Convergence: Integrating Information and Communication Technologies with Biomedicine for Global Health".

The ICBHI2015 proceedings examine enabling technologies of sensors, devices and systems that optimize the acquisition, transmission, processing, storage, retrieval, use of biomedical and health information as well as to report novel clinical applications of health information systems and the deployment of m-Health, e-Health, u-Health, p-Health and Telemedicine.

Clinical Research Informatics

Автор: Richesson
Название: Clinical Research Informatics
ISBN: 1848824475 ISBN-13(EAN): 9781848824478
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.

Principles of Biomedical Informatics,

Автор: Ira J. Kalet, PhD
Название: Principles of Biomedical Informatics,
ISBN: 0123694388 ISBN-13(EAN): 9780123694386
Издательство: Elsevier Science
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Цена: 10778.00 р.
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Описание: Gives a foundation for understanding the fundamentals of biomedical informatics, which deals with the storage, retrieval, and use of biomedical data for biological problem solving and medical decision making. This work covers the application of these principles to three biomedical domains of basic biology, clinical medicine, and public health.


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