Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases, R. Numerof; Charles A. Dinarello; Khusru Asadullah

Автор: Narula
Название: New Cytokines as Potential Drugs
ISBN: 3764358831 ISBN-13(EAN): 9783764358839
Издательство: Springer
Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics. While these products have certainly established recombinant biologics as a major pharmaceutical growth sector, the continued interest in this class of drugs arises from the fact that today we have a far better understanding of the human immune response, both at a cellular and molecular level. This has resulted in a more methodical characterisation of these factors which has given clinical researchers an opportunity to plan Phase 1 clinical trials that can provide substantial information on the activity of the cytokine in humans. Currently, a great deal of effort is also being channelled into identifying cytokines from the various DNA databases. Our major objective for this book is to profile cytokines that have been recently identified. The therapeutic potential of these cytokines based on their known properties will be discussed by the authors. The main aim of this book is to provide...

Автор: Satwant K. Narula; Robert Coffman
Название: New Cytokines as Potential Drugs
ISBN: 3034895755 ISBN-13(EAN): 9783034895750
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics.

Автор: Vijay K. Kuchroo; Nora Sarvetnick; David A. Hafler
Название: Cytokines and Autoimmune Diseases
ISBN: 0896038564 ISBN-13(EAN): 9780896038561
Издательство: Springer
Рейтинг:
Цена: 25853.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases.

Автор: Vijay K. Kuchroo; Nora Sarvetnick; David A. Hafler
Название: Cytokines and Autoimmune Diseases
ISBN: 1617372250 ISBN-13(EAN): 9781617372254
Издательство: Springer
Рейтинг:
Цена: 25853.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases.

Автор: Mantovani
Название: Pharmacology of Cytokines.2000
ISBN: 0198500424 ISBN-13(EAN): 9780198500421
Издательство: Oxford Academ
Рейтинг:
Цена: 22176.00 р.
Наличие на складе: Поставка под заказ.

Описание: Cytokines are polypeptide mediators which act as communication signals among cells of the immune system as well as among other cells and tissues in the body. They are a heterogeneous and complex group and include interferons, tumor necrosis factor and chemokines. They play a key role in homeostasis and in host defence and are involved in such inflammatory and autoimmune diseases such as rheumatoid arthritis as well as infectious diseases such as HIV infection and septic shock. Modulation of the production and action of cytokines, as well as their exploitation as therapeutic agents, has been the object of intense and competitive research. The pharmacology of cytokines is an exploding area which is entering the clinical arena. This book gives an overview of cytokine research and describes the various approaches that have been taken to develop the pharmacology of these novel mediators. Within the framework of the immunobiology of cytokines, the book examines the interactions with the cytokine system of a variety of compounds ranging from simple synthetic chemicals to biotechnological products . In addition to examining individual agents and approaches, it reviews the pathophysiology o

Автор: Christopher P. Phelps
Название: Cytokines and the Brain,6
ISBN: 044453041X ISBN-13(EAN): 9780444530417
Издательство: Elsevier Science
Рейтинг:
Цена: 27454.00 р.
Наличие на складе: Поставка под заказ.

Описание: Presents an understanding on the presence and function of CNS cytokines and their receptors in a variety of central nervous system cells during health and disease. This work demonstrates the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease.