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Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC`s), Abdel-Majid Khatib


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Автор: Abdel-Majid Khatib
Название:  Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC`s)
ISBN: 9789401780902
Издательство: Springer
Классификация:

ISBN-10: 9401780900
Обложка/Формат: Paperback
Страницы: 157
Вес: 0.25 кг.
Дата издания: 28.11.2014
Язык: English
Издание: 2006 ed.
Иллюстрации: X, 157 p.
Размер: 234 x 156 x 9
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: A New Potential Strategy in Cancer Therapy
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.
Дополнительное описание: Discovery of the Proprotein Convertases and their Inhibitors.- Signalling Pathways Leading to Furin Expression in Cancer.- PACE4 Gene Expression in Human Ovarian Cancer.- Proprotein Convertases in Tumorigenesis, Angiogenesis and Metastasis.- Proprotein Co



The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis

Автор: Domenico Ribatti
Название: The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
ISBN: 9400791577 ISBN-13(EAN): 9789400791572
Издательство: Springer
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Цена: 15672.00 р.
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Описание: 1. Introduction 2. Chorioallantoic membrane and its embryological origin 2.1. Morphology of chorioallantoic membrane blood and lymphatic vessels 2.2. A single blood sinus or a capillary plexus beneath the chorionic epithelium? 2.3. The chorioallantoic membrane vascular growth 3. Use of chorioallantoic membrane in the study of angiogenic molecules 3.1. Role of FGF-2 in chorioallantoic membrane vascularization 4. Use of chorioallantoic membrane in the study of antiangiogenic molecules 5. Use of chorioallantoic membranes in the study of tumor angiogenesis 5.1. Angiogenesis and antiangiogenesis in multiple myeloma 5.2. Angiogenesis and antiangiogenesis in human neuroblastoma 6. Use of chorioallantoic membrane in the study of tumor metastasis 6.1. Spontaneous metastasis models. 6.2. Experimental metastasis studies. 7. Other applications 7.1. In ovo and ex ovo methods 7.2. Use of chorioallantoic membrane in the study of tumor lymphangiogenesis 8. Different morphological techniques that can be used to study vascularization of the CAM and the genes involved. 9. Methods of quantifying the angiogenic response 10. Limitations of the chorioallantoic membrane assay 11. Other classical in vivo assays in comparison (advantages, disadvantages and limitations) with the chorioallantoic membrane 12. Concluding remarks Acknowledgments References

Hormonal Carcinogenesis V

Автор: Jonathan J. Li; Sara A. Li; Suresh Mohla; Henri Ro
Название: Hormonal Carcinogenesis V
ISBN: 1441923993 ISBN-13(EAN): 9781441923998
Издательство: Springer
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Цена: 38992.00 р.
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Описание: Information gathered from cell-free systems, cell cultures, animal models, and human studies, together provide important insights to our understanding of hormonal cancer causation, development, and prevention; The emerging fields of colon, lung, and pancreatic cancers in relation to hormones are examined.

Chemical Carcinogenesis

Автор: Trevor M. Penning
Название: Chemical Carcinogenesis
ISBN: 1617797294 ISBN-13(EAN): 9781617797293
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Presenting the current advances in chemical carcinogenesis, this volume promotes the view that the chemical alteration of DNA is a route cause of many cancers. Topics include the multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action.

Hormonal Carcinogenesis V

Автор: Jonathan J. Li; Sara A. Li; Suresh Mohla; Henri Ro
Название: Hormonal Carcinogenesis V
ISBN: 0387690786 ISBN-13(EAN): 9780387690780
Издательство: Springer
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Цена: 38992.00 р.
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Описание: Gathers information, from cell-free systems, cell cultures, animal models, and human studies, that provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. This title emphasises on the two major endocrine-related cancers, that is, breast and prostate.


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