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Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines, Darren R. Flower; Yvonne Perrie


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Автор: Darren R. Flower; Yvonne Perrie
Название:  Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines
ISBN: 9781489997951
Издательство: Springer
Классификация:


ISBN-10: 1489997954
Обложка/Формат: Paperback
Страницы: 314
Вес: 0.46 кг.
Дата издания: 28.01.2015
Серия: Immunomics Reviews:
Язык: English
Размер: 234 x 156 x 17
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book details the discovery of antigens and adjuvants within the context of reverse vaccinology. It explores ways to make vaccines more effective.


Vaccine Adjuvants: Methods and Protocols (Methods in Molecular Biology)

Автор: Gwyn Davies (Editor)
Название: Vaccine Adjuvants: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1607615843 ISBN-13(EAN): 9781607615842
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The study of vaccine adjuvants has developed into an exciting area of work. In this authoritative and versatile book, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products.

Subunit Vaccine Delivery

Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah
Название: Subunit Vaccine Delivery
ISBN: 1493914162 ISBN-13(EAN): 9781493914166
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.

Immunological Adjuvants and Vaccines

Автор: Gregory Gregoriadis; Anthony C. Allison; George Po
Название: Immunological Adjuvants and Vaccines
ISBN: 147570285X ISBN-13(EAN): 9781475702859
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1988

Vaccine Adjuvants

Автор: Charles J. Hackett; Donald A. Harn Jr
Название: Vaccine Adjuvants
ISBN: 1617372404 ISBN-13(EAN): 9781617372407
Издательство: Springer
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Цена: 26120.00 р.
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Описание: A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use.

Vaccine Adjuvants

Автор: Derek T. O`Hagan
Название: Vaccine Adjuvants
ISBN: 1617371599 ISBN-13(EAN): 9781617371592
Издательство: Springer
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Цена: 25853.00 р.
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Описание: Each chapter carefully reviews a single adjuvant, and suggests why a specific adjuvant might be preferred for a given antigen, depending on what type of immune response is desired. Comprehensive and highly practical, Vaccine Adjuvants: Preparation Methods and Research Protocols provides an effective guide to making and using vaccine adjuvants.

Subunit Vaccine Delivery

Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah
Название: Subunit Vaccine Delivery
ISBN: 1493948512 ISBN-13(EAN): 9781493948512
Издательство: Springer
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Цена: 19589.00 р.
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Описание:

.- 1 Immunological Background

.- 2 Classification of Vaccines

.- 3 Aluminum Adjuvants - Basic Concepts and Progress in Understanding

.- 4 Emulsions as Vaccine Adjuvants

.- 5 The application of liposomes as vaccine adjuvants

.- 6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines

.- 7 Cubosomes - Structure, Preparation and Use as an Antigen Delivery System

.- 8 ISCOMs as a Vaccine Delivery System

.- 9 Virus-like Particles, a Versatile Subunit Vaccine Platform

.- 10 Polymeric Particulates for Subunit Vaccine Delivery

.- 11 Gels as Vaccine Delivery Systems

.- 12 Implants as Sustained Release Delivery Devices for Vaccine Antigens

.- 13 Dendritic Cell-based Vaccines

.- 14 Parenteral Vaccine Administration - Tried and True

.- 15 Nasal Administration of Vaccines

.- 16 Pulmonary Administration of Subunit Vaccines

.- 17 Vaginal Delivery of Subunit Vaccines

.- 18 Transcutaneous Administration

.- 19 Pharmaceutical Analysis and Quality Control of Vaccines

.- 20 The Physical Analysis of Vaccines

.- 21 Characterizing the Association between Antigens and Adjuvants.

Vaccines and Autoimmunity

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 22485.00 р.
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Human Vaccines

Автор: Modjarrad, Kayvon
Название: Human Vaccines
ISBN: 0128023023 ISBN-13(EAN): 9780128023020
Издательство: Elsevier Science
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Цена: 13980.00 р.
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Описание:

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics--among other disciplines--that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens.

For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed

Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology.

  • Introduces new topics in vaccine immunology in the context vaccine design and production
  • Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 - 3 decades
  • Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety
  • Provides a broad overview of innovative vaccine technologies, including immunological aspects
RNA Vaccines

Автор: Kramps
Название: RNA Vaccines
ISBN: 1493964798 ISBN-13(EAN): 9781493964796
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides an overview of the field and practical hints for vaccinologists in academia and industry. Chapters provide protocols on self-replicating RNA vectors, non-replication mRNA vectors, adjuvantation and delivery, and preclinical and clinical development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Vaccines: Methods and Protocols aims to increased collaboration on RNA vaccines between basic and applied scientists in academia, government, and industry to develop future solutions for today’s challenges.

Control of Dual-Threat Agents The Vaccines for Peace Programme (Paperback)

Автор: Geissler, Erhard; Woodall, John P.
Название: Control of Dual-Threat Agents The Vaccines for Peace Programme (Paperback)
ISBN: 0198291728 ISBN-13(EAN): 9780198291725
Издательство: Oxford Academ
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Цена: 11088.00 р.
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Описание: The Vaccines for Peace (VFP) programme is designed to counter reservations about the military misuse of research into vaccines. It focuses on vaccines developed to combat those pathogens and toxins which can be used as weapon agents. In this book a range of experts from fields as diverse as biotechnology, vaccinology, international law, and diplomacy discuss the VFP programme.

Vaccine Adjuvants

Автор: Fox
Название: Vaccine Adjuvants
ISBN: 1493964437 ISBN-13(EAN): 9781493964437
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.

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