Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease, J. Robin Harris
Автор: Alan Peters; Kathleen S. Rockland Название: Cerebral Cortex ISBN: 0306446057 ISBN-13(EAN): 9780306446054 Издательство: Springer Рейтинг: Цена: 41787.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 10 is a direct continuation and extension of Volume 3 in this series, Visual Cortex.
Описание: This volume contains the proceedings of the ninth "Colloque medecine et recherche" of the Fondation IPSEN devoted to research on Alzheimer's disease. This symposium was held in Lyon on June 21, 1993, on the topic, "Amyloid Protein Precursors in Development, Aging and Alzheimer's Disease". The choice of this venue and of this particular subject was not a matter of chance. As far as the history of medicine and neurology is concerned, Lyon is doubtless one of the most famous cities in France and the F ondation IPSEN had to organize one of its meetings in this city which has been regarded for centuries as a major crossroads. Regarding the topic, the amyloid story is at the center of the debate in the field of Alzheimer's studies. For nearly 10 years, "alzheimerology" has more or less been intertwined with "amyloidology". The purification and the sequencing of the beta/ A4 peptide in amyloid congophilic angiopathy (Glenner and Wong 1984) and in Alzheimer's disease (Masters et al. 1985) were the first steps toward the numerous successes realised in the last few years. The discovery of the amyloid precursor protein (APP), the localisation of its gene on chromosome 21 and the sequencing of its cDNA in 1987 (Kang et al. 1987; Goldgaber et al. 1987; Robakis et al.
Описание: Yosemite is one of the most visited national parks, with scenery that is world-renowned. Photographer Harold Davis has explored Yosemite for years with his camera, finding the best vantage points and most photogenic times of year. Postcards in this book show Yosemite in winter, Vernal and Nevada Falls, Mirror Lake, Yosemite Valley, the view from Inspiration Point, and more
Автор: Tinker-Mill Название: Nanoscale Imaging and Characterisation of Amyloid-? ISBN: 3319395335 ISBN-13(EAN): 9783319395333 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This thesis presents a method for reliably and robustly producing samples of amyloid-? (A?) by capturing them at various stages of aggregation, as well as the results of subsequent imaging with various atomic force microscopy (AFM) methods, all of which add value to the data gathered by collecting information on the peptide’s nanomechanical, elastic, thermal or spectroscopical properties.
Amyloid-? (A?) undergoes a hierarchy of aggregation following a structural transition, making it an ideal subject of study using scanning probe microscopy (SPM), dynamic light scattering (DLS) and other physical techniques. By imaging samples of A? with Ultrasonic Force Microscopy, a detailed substructure to the morphology is revealed, which correlates well with the most advanced cryo-EM work. Early stage work in the area of thermal and spectroscopical AFM is also presented, and indicates the promise these techniques may hold for imaging sensitive and complex biological materials. This thesis demonstrates that physical techniques can be highly complementary when studying the aggregation of amyloid peptides, and allow the detection of subtle differences in their aggregation processes.
Автор: D.W. McCandles Название: Cerebral Energy Metabolism and Metabolic Encephalopathy ISBN: 1468412116 ISBN-13(EAN): 9781468412116 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The study of energy metabolism in brain is particularly interesting due to the fact that although the brain has scant energy reserves (as compared with the liver), it has one of the highest metabolic rates in the body.
Автор: Enno Freye Название: Cerebral Monitoring in the OR and ICU ISBN: 9400792662 ISBN-13(EAN): 9789400792661 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume will serve as a complete guide to the clinical application of computer assisted systems in monitoring central nervous functions both in the OR and ICU.
Автор: Payne Название: Cerebral Autoregulation ISBN: 3319317830 ISBN-13(EAN): 9783319317830 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Briefprovides a comprehensive introduction to the control of blood flow in thebrain. Beginning with the basic physiology of autoregulation, the author goeson to discuss measurement techniques, mathematical models, methods of analysis,and relevant clinical conditions, all within this single volume. The author drawstogether this disparate field, and lays the groundwork for future researchdirections. The textgives an up-to-date review of the state of the art in cerebral autoregulation,which is particularly relevant as cerebral autoregulation moves from thelaboratory to the bedside. CerebralAutoregulation will be useful to researchers in the physical sciences suchas mathematical biology, medical physics, and biomedical engineering whose workis concerned with the brain. Researchers in the medical sciences and cliniciansdealing with the brain and blood flow, as well as industry professionalsdeveloping techniques such as ultrasound, MRI, and CT will also find this Briefof interest.
Автор: Lester R. Drewes; A.Lorris Betz Название: Frontiers in Cerebral Vascular Biology ISBN: 1461362679 ISBN-13(EAN): 9781461362678 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This guide for early diagnosis and treatment of ocular and cerebral diseases offers fifty years of research on the physiology of intraocular pressure and ocular blood flow and their relation to early diagnosis and therapy of vascular diseases of the eye and brain.
Автор: Christian W. Kreipke; Jose A. Rafols Название: Cerebral Blood Flow, Metabolism, and Head Trauma ISBN: 1493901508 ISBN-13(EAN): 9781493901500 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reflecting the most recent advances in our understanding of TBI pathotrajectory, this guide is aimed at a broad range of clinicians. It suggests avenues for future research and focuses on issues such as the role of cerebral blood flow in brain trauma recovery.
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