Vesicle Trafficking in Cancer, Yosef Yarden; Gabi Tarcic
Автор: Yosef Yarden; Gabi Tarcic Название: Vesicle Trafficking in Cancer ISBN: 1461465273 ISBN-13(EAN): 9781461465270 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reports on recent progress in understanding the role of vesicular transport in cancer, including recent studies which raise the intriguing possibility that drug-mediated normalization of vesicular transport may serve as a therapeutic goal in cancer.
Автор: Winston Patrick Kuo; Shidong Jia Название: Extracellular Vesicles ISBN: 1493972510 ISBN-13(EAN): 9781493972517 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines established methods and protocols to isolate and characterize extracellular vesicles (EVs) and their composition, among other techniques including purification, imaging, biofluid-specific and cell-specific isolation and downstream genomic and proteomic profiling.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
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