DNA-Protein Interactions, Beno?t P. Leblanc; S?bastien Rodrigue
Автор: Fu Haian Название: Protein-Protein Interactions / Methods and Applications ISBN: 1588291200 ISBN-13(EAN): 9781588291202 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collection of highly successful biochemical, biophysical, genetic, and computational techniques for studying protein-protein interactions. These readily reproducible methods demonstrate how to identify protein interaction partners, qualitatively or quantitatively measure protein-protein interactions in vitro or in vivo, monitor protein-protein interactions as they occur in living cells, and determine interaction interfaces. The techniques described utilize a variety of cutting-edge technologies, including surface plasmon resonance (SRP), fluorescence resonance energy transfer (FRET), fluorescence polarization (FP), isothermal titration calorimetry (ITC), circular dichroism (CD), protein fragment complementation assays (PCA), various two-hybrid systems, and proteomics and bioinformatics-based approaches, such as the Scansite program for computational analysis. These powerful tools are essential for deciphering how proteins interact with each other to form biological networks, as well as for unraveling protein-protein interactions in disease to find novel therapeutic targets.
Автор: Mark C. Williams; L. James Maher, III Название: Biophysics of DNA-Protein Interactions ISBN: 1461426952 ISBN-13(EAN): 9781461426950 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on the biophysics of DNA-protein interactions, this volume presents new methods and results that explore the mechanism behind prtein and DNA interaction. Recent advances in biophysics are discussed, in addition to proteins that alter DNA properties to faciliate interactions for transcription or replication.
Описание: More recently, the widely expressed intuition that discrete sequences within these elements constitute binding sites for sequence-specific binding proteins has been confirmed, especially through the use of "footprinting" assays (for examples, Galas and Schmitz, 1978).
Автор: Tom Moss; Beno?t Leblanc Название: DNA-Protein Interactions ISBN: 1617378755 ISBN-13(EAN): 9781617378751 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gene expression can mean the difference between health and disease, the difference between survival and starvation. This third edition brings this vital subject up to date with protocols exploring the most cutting-edge developments in the field.
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