Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Автор: Sango Название: Schwann Cell Development and Pathology ISBN: 4431547630 ISBN-13(EAN): 9784431547631 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot-Marie-Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy and diabetic neuropathy.
Автор: S. Robert Hilfer; Joel Sheffield Название: Cell Interactions in Visual Development ISBN: 1461284015 ISBN-13(EAN): 9781461284017 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In order to provide an open forum for investigators working on all aspects of ocular development, a series of symposia on ocular and visual devel- opment was initiated in 1973.
Автор: Jean-Pierre Tassan; Jacek Z. Kubiak Название: Asymmetric Cell Division in Development, Differentiation and Cancer ISBN: 3319531492 ISBN-13(EAN): 9783319531496 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.
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