Primary Aldosteronism, Per Hellman

Автор: Hellman, MD, Ph.D
Название: Primary Aldosteronism
ISBN: 1493905082 ISBN-13(EAN): 9781493905089
Издательство: Springer
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Цена: 23508.00 р.
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Описание: Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma.

Автор: Frohlich
Название: The Local Cardiac Renin-Angiotensin Aldosterone System
ISBN: 1441905278 ISBN-13(EAN): 9781441905277
Издательство: Springer
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Цена: 32004.00 р.
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Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.

Автор: J?rg M?ller
Название: Regulation of Aldosterone Biosynthesis
ISBN: 3642831222 ISBN-13(EAN): 9783642831225
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Sixteen years is a long time, not only in human life but also in the rapid history of contemporary endocrinology. Since the publication of the first edition of this monograph, numerous new lines of research and discoveries have greatly contrib- uted to our knowledge of the physiological and pathological regulation of aldos- terone biosynthesis in man and animals. The first reports about a sensitive ra- dioimmunoassay for plasma aldosterone and about a preparation of dispersed zona glomerulosa cells were published in 1970 (Mayes et al. 1970; Haning et al. 1970). These two developments alone turned out to have a tremendous impact on research in aldosterone physiology (for reviews see Coghlan et al. 1979b; J. F. Tait et al. 1980b). In 1971, atrial natriuretic peptides, somatostatin, and the precursor molecule of ACTH had not yet been discovered. Angiotensin antagonists and con- verting-enzyme inhibitors were not yet available. The clinical syndrome of hypo- reninemic hypo aldosteronism was unknown. The possible roles of prostaglandins and dopamine in the control of aldosterone pwduction had not been considered. Cyclic AMP was then the only substance with a clearly established second-mes- senger function.

Автор: Edward D. Frohlich; Richard N. Re
Название: The Local Cardiac Renin-Angiotensin Aldosterone System
ISBN: 1489981101 ISBN-13(EAN): 9781489981103
Издательство: Springer
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Цена: 32004.00 р.
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Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.