Osteoporosis and Osteoarthritis, Jennifer J. Westendorf; Andre J. van Wijnen
Автор: Jennifer J. Westendorf; Andre J. van Wijnen Название: Osteoporosis and Osteoarthritis ISBN: 1493916181 ISBN-13(EAN): 9781493916184 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In Osteoporosis and Osteoarthritis expert investigators detail modern tools to enhance discovery in bone and cartilage biology and promote translational research in osteoporosis and osteoarthritis.
Автор: De Ceuninck Название: Cartilage and Osteoarthritis ISBN: 1588295052 ISBN-13(EAN): 9781588295057 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism
in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through
biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. Volume
2: Structure and In Vivo Analysis, offers cutting-edge procedures for the study - at the tissue level - of turnover, structure, and functioning of normal and diseased articular cartilage by
invasive and noninvasive means.
Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists with readily
reproducible protocols for new experiments to understand - from the cellular to the animal level - the pathophysiology of cartilage and to discover molecular targets for pharmacological
intervention.
Автор: Sabatini Название: Cartilage and Osteoarthritis ISBN: 1588292479 ISBN-13(EAN): 9781588292476 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism
in health and disease. Volume 1: Cellular and Molecular Tools, describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through
biochemical, biomolecular, immunological, and physical app
oaches, with emphasis on the genetic manipulation of cells. Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for studies - at the tissue level - of turnover,
structure, and functioning of normal and diseased cartilage by invasive and noninvasive means.
Comprehensive and up-to-date, the two volumes of "Cartilage and
Osteoarthritis" provide researchers and bench scientists with readily reproducible protocols for new experiments to understand - from the cellular to the animal level - the pathophysiology
of cartilage and to discover molecular targets for pharmacological intervention.
Автор: Bronner Название: Bone and Osteoarthritis ISBN: 1849966176 ISBN-13(EAN): 9781849966177 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic.
Описание: ?This book is a rich source of practical guidance on the management of relatively young patients with osteoarthritis of the knee that will assist physicians and allied health professionals in enabling patients to remain active and sustain their quality of life. It provides up-to-date knowledge on the available treatment options, describes the evidence base for each option, and identifies the appropriate timing and indications. The book opens by considering the basic science behind osteoarthritis, which is critical to management. The many nonsurgical treatment modalities are then discussed, with particular focus on the importance of a multidisciplinary approach. Subsequent chapters address the role of surgical management, covering both techniques that attempt to preserve and possibly restore the native knee joint, such as meniscal and chondral surgery, arthroscopic debridement, and osteotomy for realignment of the joint, and those that involve joint replacement. The arthroplasty component of the text encompasses all areas of prosthetic resurfacing, including localized resurfacing, unicompartmental replacement, and total knee replacement. The book has been produced in cooperation with ISAKOS and the authors constitute an international faculty who provide a truly global perspective on the subject.
Автор: H. Ralph Schumacher Название: Osteoarthritis ISBN: 3540500006 ISBN-13(EAN): 9783540500001 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The pathogenetic roles of mechanical, systemic and inflammatory factors and the importance of neurogenic factors in pain management and in the causes of disease are considered. The book will help the clinician and the investigator consider the importance of addressing different phases and subtypes of osteoarthritis in planning treatment.
Автор: J.-Y. Reginster; J.-P. Pelletier; J. Martel-Pellet Название: Osteoarthritis ISBN: 3540651276 ISBN-13(EAN): 9783540651277 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Musculoskeletal diseases are rapidly becoming a major health concern. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases.
Автор: Seisuke Tanaka; Chiaki Hamanishi Название: Advances in Osteoarthritis ISBN: 4431702458 ISBN-13(EAN): 9784431702450 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The proceedings of the symposium are presented here in five sections: (1) Mechanical stress and reactions of chondrocytes, such as intracellular ion changes, changes in the cytoskeleton, intracellular messenger systems, release of gas mediators, and changes in electromechanical properties of cartilage;
Автор: Seisuke Tanaka; Chiaki Hamanishi Название: Advances in Osteoarthritis ISBN: 4431684999 ISBN-13(EAN): 9784431684992 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The proceedings of the symposium are presented here in five sections: (1) Mechanical stress and reactions of chondrocytes, such as intracellular ion changes, changes in the cytoskeleton, intracellular messenger systems, release of gas mediators, and changes in electromechanical properties of cartilage;
Автор: J. Grifka; D.J. Ogilvie-Harris Название: Osteoarthritis ISBN: 3642877540 ISBN-13(EAN): 9783642877544 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Joint-preserving techniques for conservative and operative treatment in gonarthritis are developing rapidly. This book outlines the latest treatment options for joint preservation in osteoarthritis. These include drug treatment, viscosupplementation, arthroscopy, cartilage transplantation and osteotomy.
Описание: The term Vitamin D designates a group of closely related seco-steroids with antirachitic activity. The two most important members of these are ergocalciferol
(vitamin D2) and cholecalciferol (vitamin D3). About 80 per cent of the vitamin D supply in man is produced in the skin and only 20 per cent is provided by nutrition.
The first
analogue of Vitamin D, dihydrotachysterol, was developed in the 1930s and used in the treatment of primary or secondary hypoparathyroidism. It then took 40 years to learn that Vitamin
D was not the biologically active principle for healing bone disease. It has to be hydroxylated in the liver at position 25 to build 25-hydroxycholecalciferol and then finally in the kidney at
position 1a to become 1a, 25-dihydroxycholecalciferol [= 1a, 25-(OH)2-D3].
Further generations of Vitamin D analogues have since been developed. The most important of
these are the so-called D hormone 1a, 25-(OH)2-D3 (= calcitriol) and its analogue alfacalcidol (= 1a-OH-D3) which are highly effective drugs for the treatment of renal bone disease.
Further successful indications for active Vitamin D analogues include hypoparathyroidism and osteomalacia.
With regards osteoporosis, the role of an insufficient Vitamin D
supply or impairment in activation was underestimated for a long time. A breakthrough was achieved with studies showing that the prevalence of mild to moderate vitamin D deficiency
was very high and increasing with age.
Автор: Vincent C. Hascall; Klaus E. Kuettner Название: The Many Faces of Osteoarthritis ISBN: 3034894503 ISBN-13(EAN): 9783034894500 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Osteoarthritis is the most common joint pathology which primarily affects the older population. The disease is characterized by unique pathological changes in some synovial joints, predominantly affecting the articular cartilage, but also entire joints, including the synovial tissue and subchondral bone.
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