Adipose Tissue and Adipokines in Health and Disease, Giamila Fantuzzi; Carol Braunschweig

Автор: Yihai Cao
Название: Angiogenesis in Adipose Tissue
ISBN: 146148068X ISBN-13(EAN): 9781461480686
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book covers the latest resarch on the critical role of angiogenesis in regulating expansion and regression of adipose tissue, and explores future opportunities for targeting blood vessels as a method for treatment of obesity and metabolic diseases.

Автор: Fantuzzi Giamila
Название: Adipose Tissue and Adipokines in Health and Disease
ISBN: 1617377414 ISBN-13(EAN): 9781617377419
Издательство: Springer
Цена: 27950.00 р.
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Описание:

Adipose Tissue and Adipokines in Health and Disease presents a comprehensive survey of adipose tissue, its physiological functions, and its role in disease. This volume spans the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical studies. The authors-distinguished researchers, clinicians and epidemiologists-have incorporated groundbreaking recent studies into traditional models of adipose tissue properties. Chapters on well-known properties of adipokines leptin and adiponectin are complemented by an introduction to a novel view of adipose tissue as a dynamic organ that regulates systemic substrate availability and metabolism, along with a variety of other discrete functions. This novel concept is expanded as the role of adipose tissue in maintaining body homeostasis and the modulation of inflammatory and metabolic responses is discussed. Worldwide trends in obesity are discussed from an evolutionary perspective and causes of the current obesity epidemic are postulated. Additionally, researchers and clinicians examine the association and potential role of adipose tissue in disease mediation and offer epidemiological evidence. This volume concludes with a thoughtful and innovative discussion of various approaches to inducing and sustaining weight loss in obese patients and the health effects of such treatments. Adipose Tissue and Adipokines in Health and Disease provides a broad and substantial foundation for understanding new developments in adipose tissue biology and successfully integrating them into new research endeavors.

Автор: Jean-Philippe Bastard; Bruno F?ve
Название: Physiology and Physiopathology of Adipose Tissue
ISBN: 2817805127 ISBN-13(EAN): 9782817805122
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.

Автор: Cinti
Название: Obesity, Type 2 Diabetes and the Adipose Organ
ISBN: 3319405209 ISBN-13(EAN): 9783319405209
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This richly illustrated book provides a detailed description of the gross anatomy, light microscopy, immunohistochemistry, and electron microscopy of the adipose organ, which comprises subcutaneous and visceral fat depots. Findings in mice of differing genetic backgrounds (obesity prone and resistant) and maintained in standard and various physiologic and pathologic conditions are presented. The latter conditions include chronic cold exposure, warm exposure, fasting, pregnancy–lactation, and obesity. Features of the fetal adipose organ are described in a separate chapter, and results from transgenic mice are also presented when relevant. The human adipose organ is addressed in several chapters that include magnetic resonance and fetal findings. Most of the results regarding the adipose organ anatomy in different physiologic conditions are new, and the story of pink adipocytes (white-to-pink transdifferentiation) is quite innovative. The concept of using browning of the adipose organ as a therapeutic tool for obesity must take into consideration the anatomic and morphologic aspects described here, and the study of pink adipocytes could lead to a better comprehension of breast cancer tumor biology. This book will be of interest to all scientists who deal with obesity and related disorders.

Автор: Giamila Fantuzzi; Carol Braunschweig
Название: Adipose Tissue and Adipokines in Health and Disease
ISBN: 1627037691 ISBN-13(EAN): 9781627037693
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint.

Автор: Michael E. Symonds
Название: Adipose Tissue Biology
ISBN: 1489998322 ISBN-13(EAN): 9781489998323
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Adipose Tissue Biology provides comprehensive insight into current perspectives and challenges in the field. Both scientists and clinicians discuss topics like adipocyte precursors, differentiation and growth, brown and white adipose tissue, and more.