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Small Molecule Microarrays, Mahesh Uttamchandani; Shao Q. Yao


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Автор: Mahesh Uttamchandani; Shao Q. Yao
Название:  Small Molecule Microarrays
ISBN: 9781493958153
Издательство: Springer
Классификация:


ISBN-10: 1493958151
Обложка/Формат: Paperback
Страницы: 228
Вес: 0.46 кг.
Дата издания: 23.08.2016
Серия: Methods in Molecular Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 5 tables, black and white; xi, 228 p.
Размер: 254 x 178 x 13
Читательская аудитория: General (us: trade)
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries, peptide libraries, and carbohydrate microarrays. Written in the highly successful Methods in Molecular Biology™ series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, vital tips on troubleshooting this often difficult technology, and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous depictions of key hands-on experience and seeks to inspire a future generation of microarray practitioners to take this significant technology forward.
Дополнительное описание: The Expanding World of Small Molecule Microarrays.- Construction of Photo-Cross-Linked Microarrays of Small Molecules.- Small Molecule Microarray: Functional-Group Specific Immobilization of Small Molecules.- Detecting Protein–Small Molecule Interactions



Cell-Based Microarrays

Автор: Ella Palmer
Название: Cell-Based Microarrays
ISBN: 1493905937 ISBN-13(EAN): 9781493905935
Издательство: Springer
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Цена: 9141.00 р.
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Описание: This book is a review on the evolution of cell-based microarrays and an update to the author`s earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced significantly to include expression arrays, short interfering RNA arrays and antibody arrays.

Small Molecule Microarrays

Автор: Mahesh Uttamchandani; Shao Q. Yao
Название: Small Molecule Microarrays
ISBN: 1493965824 ISBN-13(EAN): 9781493965823
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Small molecule microarrays (SMM) were introduced in 1999 and within just a short span of time, have established themselves as a vibrant next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols consolidates a significant collection of examples, which serve to guide researchers toward ways in which SMM technology may be effectively deployed for multiplexed screening, drug discovery and ligand identification. The volume is organized into three sections covering microarray fabrication, imaging modes, and discovery approaches. The chapters cover a range of small molecule library types, ranging from synthetic combinatorial libraries to peptide and carbohydrate libraries, with lessons and techniques that can be widely applied. Written in the highly successful Methods in Molecular Biology series, format, chapters include introductions of their respective topics, lists of the requisite materials and reagents, step-by-step and readily reproducible laboratory protocols as well as vital tips on troubleshooting and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous insights into the successful applications of SMM, by experts in the field. Building on this collection of knowledge, the volume seeks to inspire a future generation of microarray practitioners to propel this significant technology to even greater heights

Microarrays in Diagnostics and Biomarker Development

Автор: Bertrand Jordan
Название: Microarrays in Diagnostics and Biomarker Development
ISBN: 3642439764 ISBN-13(EAN): 9783642439766
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. It emphasizes entities in actual clinical use as well as recent developments, such as aptamer arrays.

Peptide Microarrays

Автор: Marina Cretich; Marcella Chiari
Название: Peptide Microarrays
ISBN: 1493949683 ISBN-13(EAN): 9781493949687
Издательство: Springer
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Цена: 13275.00 р.
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Описание:

Part I: Peptide Arrays: Cutting-Edge Methods and Technology

1. Peptide Arrays on Planar Supports

Vнctor Tapia and Rudolf Volkmer

2. High-Throughput Microarray Incubations Using Multi-Well Chambers

Johannes Zerweck, Ulf Reimer, Janina Jansong, Nikolaus Pawlowski, Christoph Tersch, Maren Eckey, and Tobias Knaute

3. Analysis of Protein Tyrosine Kinase Specificity Using Positional Scanning Peptide Microarrays

Yang Deng and Benjamin E. Turk

4. Secondary Structure Determination of Peptides and Proteins After Immobilization

Stella H. North and Chris R. Taitt

5. Peptides and Anti-Peptide Antibodies for Small and Medium Scale Peptide and Anti-Peptide Affinity Microarrays: Antigenic Peptide Selection, Immobilization, and Processing

Fan Zhang, Andrea Briones, and Mikhail Soloviev

6. Low-Cost Peptide Microarrays for Mapping Continuous Antibody Epitopes

Ryan McBride, Steven R. Head, Phillip Ordoukhanian, and Mansun Law

7. The Peptide Microarray-Based Resonance Light Scattering Assay for Sensitively Detecting Intracellular Kinase Activity

Tao Li, Xia Liu, Dianjun Liu, and Zhenxin Wang

8. Anomalous Reflection of Gold: A Novel Platform for Biochips

Amir Syahir, Kin-ya Tomizaki, Kotaro Kajikawa, and Hisakazu Mihara

9. High Throughput Peptide Screening on a Bimodal Imprinting Chip Through

MS-SPRi Integration

Weizhi Wang, Qiaojun Fang, and Zhiyuan Hu

10. Analyzing Peptide Microarray Data with the R pepStat Package

Gregory Imholte, Renan Sauteraud, and Raphael Gottardo

Part II: Chemoselective Strategies to Peptide Immobilization

11. Chemoselective Strategies to Peptide and Protein Bioprobes Immobilization on Microarray Surfaces

Alessandro Gori and Renato Longhi

12. Manufacturing of Peptide Microarrays Based on Catalyst-Free Click Chemistry

Denis Prim and Marc E. Pfeifer

13. Clickable Polymeric Coating for Oriented Peptide Immobilization

Laura Sola, Alessandro Gori, Marina Cretich, Chiara Finetti, Caterina Zilio, and Marcella Chiari

14. Oriented Peptide Immobilization on Microspheres

Lisa C. Shriver-Lake, George P. Anderson, and Chris R. Taitt

15. A Cell Microarray Format: A Peptide Release System Using a Photo-Cleavable Linker for Cell Toxicity and Cell Uptake Analysis

Kenji Usui, Kin-ya Tomizaki, and Hisakazu Mihara

Part III: Peptide Microarrays for Medical Applications

16. Peptide Microarrays for

Medical Applications in Autoimmunity, Infection, and Cancer

Carsten Grцtzinger

17. Synthetic Peptide-Based ELISA and ELISpot Assay for Identifying Autoantibody Epitopes

Judit Pozsgay, Eszter Szarka, Krisztina Huber, Fruzsina Babos, Anna Magyar, Ferenc Hudecz, and Gabriella Sarmay

18. IgE and IgG4 Epitope Mapping of Food Allergens with a Peptide Microarray Immunoassay

Javier Martнnez-Botas and Belйn de la Hoz

19. IgE Epitope Mapping Using Peptide Microarray Immunoassay

Gustavo Gimenez, Sara Benedй, and Jing Lin

20. Spot Synthesis: An Optimized Microarray to Detect IgE Epitopes

Salvatore G. De-Simone and Paloma Napoleгo-Pкgo

21. Mapping of Epitopes Occurring in Bovine αs1-Casein Variants by Peptide Microarray Immunoassay

Maria Lisson and Georg Erhardt

Carbohydrate Microarrays

Автор: Yann Chevolot
Название: Carbohydrate Microarrays
ISBN: 1493958666 ISBN-13(EAN): 9781493958665
Издательство: Springer
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Цена: 16070.00 р.
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Описание: Carbohydrate microarrays emerged as a key technology for the deciphering of the glycospace by providing a multiplex technology where tens to hundreds of carbohydrates/protein interactions can be probed in parallel. Carbohydrate Microarrays: Methods and Protocols aims to give the reader the theoretical and experimental clues necessary for the fabrication and implementation of carbohydrate microarrays. This requires three essential steps: 1) to obtain the carbohydrate probes (monosacharides, oligosacchrides, polysacchairdes, glycoconjugates or glycoclusters), 2) to immobilize these probes, and 3) to implement the protocols for biological/biochemical interaction with the desired target. This volume gives an overview of carbohydrate microarray and carbohydrate chemistry and illustrates different detection techniques and their applications. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Carbohydrate Microarrays: Methods and Protocols compiles a catalogue of protocols on carbohydrate microarrays to span the needs of researchers around the globe.

Microarrays

Автор: Kilian Dill; Robin Liu; Piotr Grodzinsky
Название: Microarrays
ISBN: 1441924906 ISBN-13(EAN): 9781441924902
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions.

Protein Microarrays

Автор: Ulrike Korf
Название: Protein Microarrays
ISBN: 1493957767 ISBN-13(EAN): 9781493957767
Издательство: Springer
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Цена: 20263.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Protein microarrays can overcome the sensitivity and sample limitations of functional proteomics. This volume is an exhaustive and up-to-date presentation of robust protein microarray strategies that furthers the advance of this powerful laboratory technology.


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