Antibiotic Resistance Protocols, Stephen H. Gillespie; Timothy D. McHugh

Автор: Steven H. Gillespie, Timothy D. McHugh
Название: Antibiotic Resistance Protocols
ISBN: 160327278X ISBN-13(EAN): 9781603272780
Издательство: Springer
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Цена: 13695.00 р. 19564.00 -30%
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Описание: This book fully updates and builds upon its first edition. Beginning with chapters on epidemiology and population genetics, it continues with sections covering genomics and gene expressions, fitness mutation and physiology, and the detection of resistance.

Автор: Champney
Название: New Antibiotic Targets
ISBN: 1617378437 ISBN-13(EAN): 9781617378430
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This volume examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. The book identifies additional novel cellular targets for these new therapies. It will assist in the treatment of infectious diseases.

Автор: Gould
Название: Antibiotic Policies
ISBN: 1441934553 ISBN-13(EAN): 9781441934550
Издательство: Springer
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Цена: 30606.00 р.
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Описание: All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading.

Автор: Walsh
Название: Antibiotics: Challenges, Mechanisms, Opportunities
ISBN: 1555819303 ISBN-13(EAN): 9781555819309
Издательство: Wiley
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Цена: 16466.00 р.
Наличие на складе: Поставка под заказ.

Описание: Antibiotics: Challenges, Mechanisms, Opportunities details the contemporary challenges for discovery, optimization, and advancement of new antibiotics. It focuses on discovery not preclinical or clinical development. Given that the few classes of clinically significant antibiotics are all small molecules, this book focuses on the molecular structures and characteristics of both natural and synthetic antibacterial agents. Antibiotics is a valuable reference for microbiologists, bacterial physiologists, geneticists, pharmacologists, and drug developers. A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions:  • What are antibiotics? • Where do antibiotics come from?• How do antibiotics work? • Why do antibiotics stop working? • How should our limited inventory of effective antibiotics be addressed?  Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

Автор: Sass
Название: Antibiotics
ISBN: 1493966324 ISBN-13(EAN): 9781493966325
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, and methods for the analysis and detection of microbial adaptation strategies. Antibiotics: Methods and Protocols guides readers through chapters on production and design, mode of action, and response and susceptibility. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Antibiotics: Methods and Protocols aims to inspire scientific work in the exciting field of antibiotic research.

Автор: Champney W. Scott
Название: New Antibiotic Targets
ISBN: 1588299155 ISBN-13(EAN): 9781588299154
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. This volume features drug targets including peptide deformylase, ribosome formation, lipopolysaccharide and fatty acid biosynthesis and signal transduction pathways.

Автор: Marc Stadler; Petra Dersch
Название: How to Overcome the Antibiotic Crisis
ISBN: 3319492829 ISBN-13(EAN): 9783319492827
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria.

Автор: Muhammad Zaffar Hashmi; Vladimir Strezov; Ajit Var
Название: Antibiotics and Antibiotics Resistance Genes in Soils
ISBN: 3319662597 ISBN-13(EAN): 9783319662596
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book summarizes the current state of knowledge regarding antibiotics and antibiotics resistance genes (ARGs) in the soil environment.