Richard O. Snyder; Philippe Moullier Adeno-Associated Virus 9781493961757

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Автор: Richard O. Snyder; Philippe Moullier
Название: Adeno-Associated Virus
ISBN: 9781493961757
Издательство: Springer
Классификация:

Медицинская генетика

Генная терапия

Зоология и науки о животных

Размножение животных

ISBN-10: 1493961756
Обложка/Формат: Paperback
Страницы: 462
Вес: 0.90 кг.
Дата издания: 23.08.2016
Серия: Methods in Molecular Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 38 tables, black and white; 20 illustrations, color; 23 illustrations, black and white; xiii, 462 p. 43 illus., 20 illus. in color.; 38 tables, black and white; 20 illustrations, color; 23 illustrations, black and white; xiii, 462 p. 43 illus., 20 il
Размер: 254 x 178 x 24
Читательская аудитория: General (us: trade)
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
Дополнительное описание: Adeno-Associated Virus Biology.- Design and Construction of Functional AAV Vectors.- AAV Capsid Structure and Cell Interactions.- Exploiting Natural Diversity of AAV for the Design of Vectors With Novel Properties.- Gene Therapy in Skeletal Muscle Mediate

Adeno-Associated Virus, Richard O. Snyder; Philippe Moullier