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Peroxisome Proliferator-Activated Receptors (PPARs), Mostafa Z. Badr; Jihan A. Youssef


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Автор: Mostafa Z. Badr; Jihan A. Youssef
Название:  Peroxisome Proliferator-Activated Receptors (PPARs)
ISBN: 9781493962570
Издательство: Springer
Классификация:
ISBN-10: 1493962574
Обложка/Формат: Paperback
Страницы: 343
Вес: 0.62 кг.
Дата издания: 23.08.2016
Серия: Methods in Molecular Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 18 tables, black and white; xi, 343 p.
Размер: 254 x 178 x 19
Читательская аудитория: General (us: trade)
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology but differ in function, tissue distribution and ligand specificity. PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, and efforts are currently underway to fully characterize their functioning and to develop safer and more effective PPAR modulators to treat a myriad of diseases and conditions. In Peroxisome proliferator-Activated Receptors: Methods and Protocols, renowned experts in the PPAR arena provide detailed protocols for investigating these receptors. Chapters contain methods ranging from the cloning of receptors to their knockdown, to protocols exploring posttranslational modifications of PPARs and coactivators, as well as receptor subcellular localization. Also assembled are methods to evaluate the involvement of these receptors in behavior functions, an emerging facet in PPAR research. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. With its well-honed methodologies, Peroxisome proliferator-Activated Receptors: Methods and Protocols, will be a useful resource for all seeking to advance their knowledge of this field.
Дополнительное описание: PPARs: History and Advances.- PPAR-Alpha Cloning, Expression and Characterization.- PPARGC1A and PPARG Genotyping. Beginner’s Guide to Genotyping with Unlabeled Probes.- Generation of an Inducible, Cardiomyocyte-Specific Transgenic Mouse Model with PPAR?/



Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

Автор: J.-C. Fruchart; Antonio M. Gotto Jr.; Rodolfo Paol
Название: Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications
ISBN: 1461354277 ISBN-13(EAN): 9781461354277
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control.

Peroxisome Proliferator-Activated Receptors

Автор: Jihan A. Youssef; Mostafa Z. Badr
Название: Peroxisome Proliferator-Activated Receptors
ISBN: 1627034196 ISBN-13(EAN): 9781627034197
Издательство: Springer
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Цена: 22203.00 р.
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Описание: This book reviews the history of PPAR discovery and details receptor structure and its posttranslational modifications, discusses endogenous and exogenous ligands, the tissue distribution and versatile functions of PPAR subtypes in major organs and much more.

Peroxisomes

Автор: Norbert Latruffe; Maurice Bugaut
Название: Peroxisomes
ISBN: 3642878091 ISBN-13(EAN): 9783642878091
Издательство: Springer
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Цена: 6986.00 р.
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Inborn Errors of Cellular Organelles: Peroxisomes and Mitochondria

Автор: R.J. Pollitt; A.H. van Gennip; C.J. de Groot; G.M.
Название: Inborn Errors of Cellular Organelles: Peroxisomes and Mitochondria
ISBN: 9401079277 ISBN-13(EAN): 9789401079273
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Proceedings of the 24th Annual Symposium of the SSIEM held in Amersfoort, the Netherlands, September 1986.

Stress-Activated Protein Kinases

Автор: Francesc Posas; Angel R. Nebreda
Название: Stress-Activated Protein Kinases
ISBN: 3642094805 ISBN-13(EAN): 9783642094804
Издательство: Springer
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Цена: 40389.00 р.
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Описание: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals.

The Microbiology of Activated Sludge

Автор: Robert J. Seviour; L. Blackall
Название: The Microbiology of Activated Sludge
ISBN: 9401057540 ISBN-13(EAN): 9789401057547
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This book is not meant to compete directly with the books by Gray (1989, 1990) nor the excellent manual published by Jenkins and coworkers (1993b), which has been invaluable to us and others trying to identify filamentous bacteria.

Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

Автор: J.-C. Fruchart; Antonio M. Gotto Jr.; Rodolfo Paol
Название: Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications
ISBN: 140207199X ISBN-13(EAN): 9781402071997
Издательство: Springer
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Цена: 27951.00 р.
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Описание: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. This volume provides a view of the clinical and scientific developments within this area of study.

Peroxisome Proliferator-Activated Receptors

Автор: Jihan A. Youssef; Mostafa Z. Badr
Название: Peroxisome Proliferator-Activated Receptors
ISBN: 1627038868 ISBN-13(EAN): 9781627038867
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book reviews the history of PPAR discovery and details receptor structure and its posttranslational modifications, discusses endogenous and exogenous ligands, the tissue distribution and versatile functions of PPAR subtypes in major organs and much more.

Peroxisomes in Biology and Medicine

Автор: H. Dariush Fahimi; Helmut Sies
Название: Peroxisomes in Biology and Medicine
ISBN: 3642713270 ISBN-13(EAN): 9783642713279
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Peroxisomes (microbodies) have a long evolutionary lifespan, but in cell biology they are still young. It is gratifying to see that most recent advances in our knowledge of peroxisomes come from quite different disciplines, ranging from molecular biology and cell biology to clinical research. The identification in terms of cDNA sequences of enzymes, the localization in terms of immuno-electron microscopy, and the cell biological aspects of the organelle biogenesis have seen substantial progress very recently. Likewise, the phenomenon of peroxisome proliferation induced by a number of drugs, e. g. hypolipidemics and plasticizers, constitute an active area of research, where much is still to be learnt. The medical problem of inborn errors of metabolism seems to have gained a new realm for discovery. Here, the advances in knowledge within the last year have been particularly striking. Therefore, the "International Symposium on Peroxisomes in Biology and Medicine," held in Heidelberg from July 14-17,1986, was even more excit- ing than could have initially been anticipated. The present volume consists of papers from that conference. For sake of rapid publication, the camera- ready format, inspite of all its drawbacks (e. g. no proof reading by authors), was chosen. It is our pleasure to acknowledge support and help. The Symposium was supported by Deutsche Forschungsgemeinschaft, Bonn, by the Ministerium ftir Wissenschaft und Kunst Baden-Wtirttemberg, Stuttgart, as well as by a number of generous contributors from industry.

Plant Peroxisomes

Автор: A. Baker; I.A. Graham
Название: Plant Peroxisomes
ISBN: 9048160073 ISBN-13(EAN): 9789048160075
Издательство: Springer
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Цена: 43184.00 р.
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Описание: In the two decades since the last comprehensive work on plant peroxisomes appeared, the scientific approaches employed in the study of plant biology have changed beyond all recognition.

Peroxisomes and their Key Role in Cellular Signaling and Metabolism

Автор: Luis A. del R?o
Название: Peroxisomes and their Key Role in Cellular Signaling and Metabolism
ISBN: 9401782903 ISBN-13(EAN): 9789401782906
Издательство: Springer
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Описание: Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism.

Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions

Автор: William R. Bartle; Volker Braun; John M. Dietschy;
Название: Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions
ISBN: 3642729045 ISBN-13(EAN): 9783642729041
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Since it has been demonstrated that reducing the steady-state plasma LDL-cholesterol concentration produces a proportional decrease in the risk of developing atherosclerosis 2), a major effort is now underway to develop safe and effective lipid lowering agents.


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