Автор: Elisa Vicenzi; Guido Poli Название: Human Retroviruses ISBN: 1627036695 ISBN-13(EAN): 9781627036696 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human Retroviruses: Methods and Protocols collects key experimental protocols that have provided the basis of the major discoveries of the field. Split into five sections, this detailed volume covers mapping of the HIV life cycle, isolation, co-receptor use, and cell tropism of HIV-1, in vivo quantification of HIV-1, biological aspects of HIV-1, as well as HTLVs. Some articles explore "assay and function of accessory genes", largely involving the interface between retroviral and host factors, the extracellular role of Tat and Tax, resembling the function of cytokines, and the biotechnological exploitation of HIV as lentiviral vector to carry foreign genes with therapeutic value. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and authoritative, Human Retroviruses: Methods and Protocols provides state-of-art methodological protocols from world leaders in human retrovirology, essential for any lab working this vital field.
Автор: Irvin S.Y. Chen; Hilary Koprowski; A. Srinivasan; Название: Transacting Functions of Human Retroviruses ISBN: 3642789315 ISBN-13(EAN): 9783642789311 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are three major types of human retroviruses, namely HIV, HTLV, and endogenous human retroviruses. This book presents the various findings on the replication of these human retroviruses. It is suitable for students, researchers and medical professionals.
Автор: Robert C. Gallo; Dominique Stehelin; Oliviero E. V Название: International Symposium: Retroviruses and Human Pathology ISBN: 1461293960 ISBN-13(EAN): 9781461293965 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases.
Автор: Robert C. Gallo; Dominique Stehelin; Oliviero E. V Название: International Symposium: Retroviruses and Human Pathology ISBN: 0896030989 ISBN-13(EAN): 9780896030985 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases.
Автор: Jaquelin Dudley Название: Retroviruses and Insights into Cancer ISBN: 1489981438 ISBN-13(EAN): 9781489981431 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book contains a series of review articles that focus on retroviral models of human and animal cancers. The reviews summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.
Автор: Ronald Swanstrom; Peter K. Vogt Название: Retroviruses ISBN: 3642752209 ISBN-13(EAN): 9783642752209 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Among the first diseases for which a viral etiology was esta- blished were tumors, lymphomas, and sarcomas in chickens, shown by Ellermann and Bang (1908) and Rous (1910) to be transmissible with cell-free filtrates. The broad significance of these discoveries was not fully recognized at first, mainly because chickens were perceived as too distanly related to humans to provide useful and relevant models for human disease. Change came slowly. In 1936 Bittner found that a viral agent is involved in the causation of mammary cancer in mice, and in 1957 Gross discovered the first murine leukemia virus. In the years following numerous tumor-inducing viruses, infecting all classes of verte- brates, were isolated. The decisive impulse for the development of the RNA tumor virus field sprang from advances in cell culture. In 1958 Temin and Rubin, following initial observations of Manaker and Groupe, worked out the conditions for virus-induced tumori- genic transformation in cell culture and made this transform- ation the basis for a quantitative assay of viral infectivity and oncogenicity. The genetic and cell biological studies that grew out of Rubin's and Temin's groundwork quickly brought into focus two puzzling problems: a requirement for DNA synthesis early in the lifecycle of the RNA tumor viruses, and the existence of genetic information in the virus that is needed for oncogenesis but not for virus reproduction.
Автор: Peter K. Vogt Название: Oncogenes and Retroviruses ISBN: 3642747027 ISBN-13(EAN): 9783642747021 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The newest volume in the Current Topics in Microbiology and Immunology series edited by Dr. Vogt and dealing with oncogenes and retroviruses contains four review articles by international authorities in the field.
Автор: P.K. Vogt; H. Koprowski Название: Retroviruses 2 ISBN: 3642690777 ISBN-13(EAN): 9783642690778 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: P.K. Vogt; H. Koprowski Название: Retroviruses 1 ISBN: 3642689450 ISBN-13(EAN): 9783642689451 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1 Scope of the Review This review was intended initially as a reference source for those interested in the origins and fITst descriptions ofthe defective avian sarcoma viruses.
Автор: P.K. Vogt; H. Koprowski Название: Retroviruses 4 ISBN: 3642708129 ISBN-13(EAN): 9783642708121 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The technique of microinjection along with viral genetics and molecular biology has proven useful in the correlation of retroviral polynucleotide structure with function. The advantage of this technique is the involvement of living cells where rare activities may be observed and where properties of living cells can be assayed. Future studies involving recombinant DNA molecules and the asso- ciation of proteins with nucleic acids promise to yield additional insight into the nucleotide sequences involved in the expression of viral activities. References Anderson SM, Chen JH (1981) In vitro translation of avian myeloblastosis virus RNA. J Virol 40: 107-117 Berget SM, Moore C, Sharp PA (1977) Spliced segments of the 5' terminus of adenovirus 2 late mRNA. Proc Nat Acad Sci USA 74:3171-3175 Bishop JM (1978) Retroviruses. Annu Rev Biochem 47:35-88 Capecchi MR (1980) High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22:479-488 Chien, Y-H, Junghans RP, Davidson W (1980) Electron microscopic analysis of the structure of RNA tumor virus nucleic acids. In: Stephenson JR (ed) Molecular biology of RNA tumor viruses.
Автор: P.K. Vogt; H. Koprowski Название: Retroviruses 3 ISBN: 3642696791 ISBN-13(EAN): 9783642696794 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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