In Silico Models for Drug Discovery, Sandhya Kortagere

Название: In Silico Drug Discovery & Design,
ISBN: 148221783X ISBN-13(EAN): 9781482217834
Издательство: Taylor&Francis
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Описание: This text provides an overview of the current methodological strategies in computer-aided drug discovery and design.

Автор: Darren D.R. Flower; Jon Timmis
Название: In Silico Immunology
ISBN: 1441942645 ISBN-13(EAN): 9781441942647
Издательство: Springer
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Описание: This book outlines three emergent disciplines, which are now poised to engineer a paradigm shift from hypothesis- to data-driven research: theoretical immunology, immunoinformatics, and Artificial Immune Systems. Coverage shows how these three are set to transform immunological science and the future of health care.

Автор: Goyal
Название: In silico Modeling and Experimental Validation for Improving Methanogenesis from CO2 via M. maripaludis
ISBN: 9811025096 ISBN-13(EAN): 9789811025099
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This thesis explores the ability of M. maripaludis to capture and convert CO2 to methane in the presence of free nitrogen, and offers a consolidated review of the metabolic processes and applications of M. maripaludis. Further, it develops, validates and analyzes the first genome-scale metabolic model (iMM518) of M. maripaludis. Readers will discover, for the first time, the impact of nitrogen fixation on methane production. As such, the thesis will be of interest to researchers working on M. maripaludis, biofuels and bioenergy, systems biology modeling and its experimental validation, estimation of maintenance energy parameters, nitrogen fixing microbes, and bioremediation.

Автор: Sandhya Kortagere
Название: In Silico Models for Drug Discovery
ISBN: 1627033416 ISBN-13(EAN): 9781627033411
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This Methods in Molecular Biology (TM) book surveys in silico models, offering techniques to derive novel antimicrobial targets and methods for computing binding energies of drugs to their target proteins, plus protocols, materials lists, known pitfalls and more.

Автор: Benfenati
Название: In Silico Methods for Predicting Drug Toxicity
ISBN: 1493936077 ISBN-13(EAN): 9781493936076
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This detailed volume explores in silico methods forpharmaceutical toxicity by combiningthe theoretical advanced research with the practical application of the tools.Beginning with a section covering sophisticated models addressing the bindingto receptors, pharmacokinetics and adsorption, metabolism, distribution, andexcretion, the book continues with chapters delving into models for specifictoxicological and ecotoxicological endpoints, as well as broad views of themain initiatives and new perspectives which will very likely improve our way ofmodelling pharmaceuticals. Written for the highly successful Methods in Molecular Biology series,chapters include the kind of detailed implementation advice that is key forachieving successful research results.Authoritative and practical, In Silico Methods for Predicting DrugToxicity offers the advantage of incorporating data and knowledge fromdifferent fields, such as chemistry, biology, -omics, and pharmacology, toachieve goals in this vital area of research.

Автор: Kendall N. Houk; Christopher A. Hunter; Michael J.
Название: Silicon Chemistry II
ISBN: 3662155583 ISBN-13(EAN): 9783662155585
Издательство: Springer
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Цена: 15672.00 р.
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Автор: Werner E. G. M?ller
Название: Silicon Biomineralization
ISBN: 3642624510 ISBN-13(EAN): 9783642624513
Издательство: Springer
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Цена: 26122.00 р.
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Описание: The volume is intended for biologists, biochemists and molecular biologists, involved in the understanding of structure formation in living organisms and will also be very useful for scientists working in the field of applied Nanotechnology and Nanobiotechnology.

Автор: Gerd Bendz
Название: Biochemistry of Silicon and Related Problems
ISBN: 1461340209 ISBN-13(EAN): 9781461340201
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Silicon chemistry was initiated in 1823 by Berzelius who prepared elemental silicon. In many ways silicon was considered a typical opposite of carbon, although the two elements are closely related as to their electronic structure, both having four valence electrons. silicon by polar silicon- -oxygen-silicon bonds.

Автор: Gabriele Proetzel; Michael V. Wiles
Название: Mouse Models for Drug Discovery
ISBN: 149393659X ISBN-13(EAN): 9781493936595
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Herein, these models are appliedto a wide field of disease areas, including diabetes, cardiovascular disease,skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinaldisorders, as well as various behavioral models.

Автор: Gabriele Proetzel; Michael V. Wiles
Название: Mouse Models for Drug Discovery
ISBN: 1493961217 ISBN-13(EAN): 9781493961214
Издательство: Springer
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Цена: 20263.00 р.
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Описание: With its versatility, ease of use and similarity to the human genome, the mouse has become a top model for medical study. This book provides background of mice as models and details a collection of techniques for a wide variety of specific disease topics.