Hepatitis B Virus in Human Diseases, Yun-Fan Liaw; Fabien Zoulim
Автор: Thomas HC Название: Viral Hepatitis 4ed. ISBN: 0470672951 ISBN-13(EAN): 9780470672952 Издательство: Wiley Рейтинг: Цена: 31038.00 р. Наличие на складе: Поставка под заказ.
Описание: The 4th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and mortality.
Автор: Haitao Guo; Andrea Cuconati Название: Hepatitis B Virus ISBN: 1493966987 ISBN-13(EAN): 9781493966981 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume serves as a reference for the dissemination of advances made in the study of Hepatitis B Virus (HBV). Hepatitis B Virus: Methods and Protocols details protocols and techniques ranging from cell culture studies to in vivo and clinical immunology. The chapters in this book discuss treatments of in vitro infection systems, analysis and quantification of cccDNA and its mutations; in vitro polymerase activity assays; cellular trafficking of core proteins; intracellular calcium metabolism; detection, cloning, and sequencing of HBV markers; and new strategies aimed at exploiting new mechanisms for drug discovery. The book also covers classical methods for resolution of extracellular viral particles by native gel electrophoresis, and methods for detecting HBV antigens in drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Hepatitis B Virus: Methods and Protocols is a valuable tool for researchers to use toward their advanced studies in HBV.
Автор: Miyamura Название: Hepatitis C Virus I ISBN: 4431560963 ISBN-13(EAN): 9784431560968 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is composed of chapters that review important fundamental aspects of HCV biology and disease pathogenesis including, for example, the discovery and identification of the HCV genome, early virus-cell interactions including identification of various cellular receptors, HCV gene expression studied using the HCV replicon system, identification and characterization of HCV structural- and non-structural HCV proteins, HCV replication in cultured cells, and host factors involved in viral replication. This volume also contains chapters dealing with immunity to HCV infection and pathogenesis. This is particularly important in understanding hepatitis C because HCV infection alone is not cell lytic. Mechanisms underlying the persistent nature of HCV infection are also discussed in these chapters. Many of the authors published articles that were listed among the “top 10 papers” published in the 24 years since HCV was discovered in 1989. Their citations are above 1,000 (Web of Science). The authors describe the background and significance of their contributions to the field in the context of findings from other research groups.
Автор: Berenguer Название: Hepatitis C Virus and Liver Transplantation ISBN: 1461484375 ISBN-13(EAN): 9781461484370 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides up-to-date information on the application of new therapies to the field of liver transplantation. It examines their efficacy, the management of side effects as well as potential interactions and specific problems associated with their use.
Автор: Ralf Bartenschlager Название: Hepatitis C Virus: From Molecular Virology to Antiviral Therapy ISBN: 364242936X ISBN-13(EAN): 9783642429361 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected.
Автор: Emilio Jirillo Название: Hepatitis C Virus Disease ISBN: 1441924388 ISBN-13(EAN): 9781441924384 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite numerous hepatitis C virus infection studies, its pathogenesis and medical treatment have not been fully explained. This comprehensive volume, written by experts in the field, covers the most recent advances in the study of HCV, moving from basic research to clinical applications.
Автор: M.B. Ray Название: Hepatitis B Virus Antigens in Tissues ISBN: 9401162379 ISBN-13(EAN): 9789401162371 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This has resulted in the compilation of original results and new insights into the cellular and tissular localization of the anti- genic components of the hepatitis B virus in different forms of chronic liver disease.
Автор: Yun-Fan Liaw; Fabien Zoulim Название: Hepatitis B Virus in Human Diseases ISBN: 3319223291 ISBN-13(EAN): 9783319223292 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for students, clinicians, and researchers with an interest in hepatitis B. The book reviews new data about basic and translational science including the viral life cycle, the immunopathogenesis of virus induced chronic hepatitis, the mechanism of virus induced liver cancer, and their potential applications for the clinical management of patients. The clinical aspects of this chronic viral infection are reviewed in detail with important chapters on the global epidemiology, the natural history of the disease, co-infections with its satellite virus HDV or HIV, and management of special patient populations. A major emphasis is made on the management of antiviral therapy and the recent international guidelines for the treatment of hepatitis B. Finally, the book reviews the current state of the art regarding immunoprophylaxis to prevent the spread of the virus and its major clinical consequences. The new advances and perspectives in the development of improved antiviral treatments are also discussed.Hepatitis B Virus in Human Diseases will serve as a very useful resource for students, physicians and researchers dealing with, and interested in, this challenging chronic viral infection. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Автор: Tatsuo Miyamura; Stanley M. Lemon; Christopher M. Название: Hepatitis C Virus II ISBN: 4431560998 ISBN-13(EAN): 9784431560999 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book helps scientists, clinicians and otherinterested individuals understand recent clinical advances and challenges forthe future. It covers many basic aspects of the pathogenesis of chronic hepatitisC, HCV infections in particular populations, approaches to therapy, andprevention and control of HCV Infection. The book provides a succinct review ofthe large amount of data generated by multiple groups over the past two decadesthat has revealed the natural history of HCV infection. Similarly, itsummarizes current understanding of the origins of HCV-associatedhepatocellular carcinoma, cirrhosis and hepatic fibrosis. Extra-hepaticmanifestation and metabolic disorders related to HCV infection are described.In this volume, these clinically important aspects of HCV infection arecomprehensively described. Highlights are description of newly developed direct- acting antivirals. The authors represent a worldwidedistribution of leaders in the field reflecting the global nature of HCVinfection. Based on recent data concerning the genetic- and geographicaldiversity of HCV, and increased global disease burden of HCV infection, challenges for global control of HCV infections are described.
Автор: Marina Berenguer Название: Hepatitis C Virus and Liver Transplantation ISBN: 1493946064 ISBN-13(EAN): 9781493946068 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hepatitis C Virus and Liver Transplantation is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to the field of liver transplantation and hepatitis C virus infection. The sections of the book have been structured to review the overall scope of issues of recurrent hepatitis C in different complex settings, including retransplantation, HIV-coinfected patients or in the setting of suboptimal graft donors. This book provides up-to-date information on the application of new therapies to the field of liver transplantation. It provides the most recent data on their efficacy, the management of side effects, as well as the potential interactions and specific problems associated with their use in the transplant setting. Finally, an appraisal of the risks and benefits of using organs from anti-HCV positive donors is presented. This book provides concise and actual materials for several important topics that are simply not adequately covered by current available literature. Hepatitis C Virus and Liver Transplantation will provide a unique and valuable resource in the field of liver transplantation and will be of great value to Hepatologists, Transplant and Abdominal Surgeons, Oncologists, as well as Fellows and Residents training in these fields.
Описание: Innate immunity in Type C Hepatitis.- Mechanisms of Interferon Action and Resistance: Lessons learned from cell cultures studies.- Immunological Parameters Determining the Outcome of Hepatitis C Virus Infection.- The Effects of Interferon-Alpha Therapy on Immune Response and Outcome.- Microbial Components Associated with HCV Disease Interfere with Response to Interferon-alpha/Ribavarin Treatment.- IFN-induced Effector Proteins and HCV Replication.- Treatment of Chronic Hepatitis C with Various Genotypes.- IFNs in HCV infection: Biological and Clinical Considerations.- Clinical application of IFN-based therapy for HCV.- HCV therapy in difficult-to-treat patients.- Effects of IFN-alpha/Ribavirin Treatment on HCV Disease and Related Progression.
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