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Practical Protein Bioinformatics, Florencio Pazos; M?nica Chagoyen


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Автор: Florencio Pazos; M?nica Chagoyen
Название:  Practical Protein Bioinformatics
ISBN: 9783319381848
Издательство: Springer
Классификация:




ISBN-10: 3319381849
Обложка/Формат: Paperback
Страницы: 106
Вес: 0.17 кг.
Дата издания: 23.08.2016
Язык: English
Размер: 234 x 156 x 6
Основная тема: Life Sciences
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

INTRODUCTION

1. SEQUENCES
- INTRODUCTION
- REPRESENTING PROTEIN SEQUENCES IN THE COMPUTER Sequence file formats
Sequence format conversion tools
MAIN PROTEIN SEQUENCE DATABASES
BASIC SEQUENCE-BASED CHARACTERISTICS
COMPARE TWO PROTEIN SEQUENCES
Types of pair-wise sequence alignments
FINDING SIMILAR SEQUENCES IN A DATABASE (BASIC)
Which sequence database to search?
BLAST
COMPARE MORE THAN TWO SEQUENCES
Multiple Sequence Alignments: Formats and Conversion
Alignment editing and representation
Summarizing MSAs
FINDING SIMILAR SEQUENCES IN A DATABASE (ADVANCED) Sequence profiles
Iterative profile construction
HMM profile search against a sequence database
HMM profile search against a profile database
PROTEIN MOTIFS, DOMAINS AND FAMILIES
BASIC PHYLOGENY

2. STRUCTURES
INTRODUCTION
Storing protein structures - The PDB file format
MAIN PROTEIN STRUCTURE DATABASES
Classifications of structural domains
STRUCTURE MANIPULATION, VISUALIZATION AND COMPARISON
Structure Manipulation and Visualization
Structure Comparison
PREDICTION OF 1D STRUCTURAL FEATURES
Secondary structure and solvent accessibility
Transmembrane segments
Coiled-coils
Disordered regions
Protein sorting signals
PREDICTING PROTEIN 3D STRUCTURE
Template-based (homology-based approaches)
Template-based (fragment-based approaches)
Model quality checks
ANALYSIS OF PROTEIN STRUCTURE
Mapping conservation
Protein and ligand contacts
Surface clefts, binding pockets, tunnels and internal cavities

3. SYSTEMS
INTRODUCTION
Protein/gene functional annotations
ID conversions
ANNOTATION ENRICHMENT ANALYSIS OF LARGE PROTEINS SETS
PROTEIN INTERACTION NETWORKS
METABOLIC NETWORKS
Retrieve the metabolic-related information associated to a protein of interest
Map a large set of proteins in the metabolome
OTHER BIOLOGICAL NETWORKS

BIBLIOGRAPHY

HOW TO

TOOLS INDEX




Oxford American Handbook of Clinical Examination and Practical Skills

Автор: Burns, Elizabeth Korn, Kenneth Whyte, James, IV
Название: Oxford American Handbook of Clinical Examination and Practical Skills
ISBN: 0195389727 ISBN-13(EAN): 9780195389722
Издательство: Oxford Academ
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Цена: 10613.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Over 200 color figures and concise, readable text guide students through the steps to perform a thorough and effective clinical examination and perform basic practical skills.

Practical Bioinformatics

Автор: Bujnicki Janusz M.
Название: Practical Bioinformatics
ISBN: 3540206132 ISBN-13(EAN): 9783540206132
Издательство: Springer
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The book is unique in that. It bridges the gap between bioinformaticists and molecular biologists, i.e. the developers and the users of computational methods for biological data analysis and in that it presents examples of practical applications of the bioinformatics tools in the "daily practice" of an experimental research scientist. The book starts with reviews on computational methods for protein sequence-structure-function analysis (sequence studies, structure prediction), followed by methods that explicitly utilize experimental data routinely obtained in the laboratory to improve the functional predictions. The second part comprises a series of examples on how particular applications of different types of bioinformatics methods in combination with experimental studies to validate the hypotheses have led to important scientific discoveries. Therefore, the book is a guide to application of bioinformatics methods in molecular biology, addressed mainly to the research scientists, postdocs, and advanced graduate students.

Practical Protein Bioinformatics

Автор: Florencio Pazos; M?nica Chagoyen
Название: Practical Protein Bioinformatics
ISBN: 3319127268 ISBN-13(EAN): 9783319127262
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools is based on the experience of the authors that lead a protein bioinformatics facility in a large research centre, with the additional constraint that the tools should be accessible through standard web browsers without requiring the local installation of specific software, command-line tools, etc. The web tools covered include those aimed to retrieve protein information, look for similar proteins, generate pair-wise and multiple sequence alignments of protein sequences, work with protein domains and motifs, study the phylogeny of a family of proteins, retrieve, manipulate and visualize protein three-dimensional structures, predict protein structural features as well as whole three-dimensional structures, extract biological information from protein structures, summarize large protein sets, study protein interaction and metabolic networks, etc. The book is associated to a dynamic web site that will reflect changes in the web addresses of the tools, updates of these, etc. It also contains QR codes that can be scanned with any device to direct its browser to the tool web site. This monograph will be most valuable for researchers in experimental labs without specific knowledge on bioinformatics or computing.

Protein Bioinformatics

Автор: Cathy H. Wu; Cecilia N. Arighi; Karen E. Ross
Название: Protein Bioinformatics
ISBN: 1493967819 ISBN-13(EAN): 9781493967810
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
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Описание: This volume introduces bioinformatics research methods for proteins, with special focus on protein post-translational modifications (PTMs) and networks.

High-Performance Computational Solutions in Protein Bioinformatics

Автор: Dariusz Mrozek
Название: High-Performance Computational Solutions in Protein Bioinformatics
ISBN: 3319069705 ISBN-13(EAN): 9783319069708
Издательство: Springer
Рейтинг:
Цена: 6986.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This work focuses on proteins and their structures, protein structure similarity searching at main representation levels and various techniques that can be used to accelerate similarity searches.

Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis

Автор: Ingvar Eidhammer
Название: Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis
ISBN: 0470848391 ISBN-13(EAN): 9780470848395
Издательство: Wiley
Рейтинг:
Цена: 12189.00 р.
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Описание: This book takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective. Key features of the book include:* Provides a comprehensive introduction to the analysis of protein sequence and structure analysis.

Evolutionary bioinformatics /

Автор: Forsdyke, Donald R.
Название: Evolutionary bioinformatics /
ISBN: 3319287532 ISBN-13(EAN): 9783319287539
Издательство: Springer
Рейтинг:
Цена: 26552.00 р.
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Описание: Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people.


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