Автор: Val?rie Gabelica Название: Nucleic Acids in the Gas Phase ISBN: 3642548415 ISBN-13(EAN): 9783642548413 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life. This volume introduces techniques used to investigate the properties of nucleic acids in the absence of solvent. It highlights the specificities pertaining to the studies of nucleic acids, although some of the techniques can similarly be applied to the study of other biomolecules, like proteins. The first part of the book introduces the techniques, from the transfer of nucleic acids to the gas-phase, to their detailed physico-chemical investigation. Each chapter is devoted to a specific molecular property, and illustrates how various approaches (experimental and theoretical) can be combined for the interpretation. The second part of the book is devoted to applying the gas-phase approaches to solve specific questions related to the biophysics, biochemistry or pharmacology of nucleic acids.
Автор: JORGEN KJEMS, Elena Ferapontova, Kurt V. Gothelf Название: Nucleic Acid Nanotechnology ISBN: 3642388140 ISBN-13(EAN): 9783642388149 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the intersection of nucleic acid research with nanotechnology, including advances in synthetic modifications, applications in bioengineering, nanoscale design, medicine, genetic analysis, chemistry, molecular biology and material science.
Автор: Yo Kikuchi; Elena Y. Rykova Название: Extracellular Nucleic Acids ISBN: 3642264190 ISBN-13(EAN): 9783642264191 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Following their emergence as key players in biology and the medical sciences, this book covers newly developing fields related to extracellular nucleic acids, including their basic biology, their ecology and their implications for medical science.
Описание: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications.
Автор: Astrid Sigel; Helmut Sigel; Roland K. O. Sigel Название: Interplay between Metal Ions and Nucleic Acids ISBN: 9401782946 ISBN-13(EAN): 9789401782944 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions;
Автор: Volker A. Erdmann; Jan Barciszewski Название: From Nucleic Acids Sequences to Molecular Medicine ISBN: 364243083X ISBN-13(EAN): 9783642430831 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading experts in the field , this book covers hot topics such as small interference RNAs for gene silencing in molecular biology and medicine. Includes numerous illustrations.
Автор: Neidle, Stephen Название: Therapeutic Applications of Quadruplex Nucleic Acids ISBN: 0128103728 ISBN-13(EAN): 9780128103722 Издательство: Elsevier Science Рейтинг: Цена: 15327.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the design of quadruplex-selective small-molecule ligandsand the study of their cellular effects. This timely publication gives a uniquely integrated view of quadruplex nucleic acids that will be a major resource in future drug-discovery strategies.Therapeutic Applications of Quadruplex Nucleic Acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics.Written by a world leader in this field, this book is a vital resource for researchers in medicinal chemistry, chemical biology, structural biology, drug discovery, and pharmacology in cancer and other therapeutic areas, as well as for chemists and biologists working on nucleic acids, and will be useful for both active researchers and students in these areas.
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