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Cardiac Energy Metabolism in Health and Disease, Gary D. Lopaschuk; Naranjan S. Dhalla


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Автор: Gary D. Lopaschuk; Naranjan S. Dhalla
Название:  Cardiac Energy Metabolism in Health and Disease
ISBN: 9781493948796
Издательство: Springer
Классификация:


ISBN-10: 1493948792
Обложка/Формат: Paperback
Страницы: 295
Вес: 0.44 кг.
Дата издания: 22.09.2016
Серия: Advances in Biochemistry in Health and Disease
Язык: English
Размер: 157 x 234 x 24
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease.

Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.




Cardiac Pacing and Defibrillation in Pediatric and  Congenital Heart Disease

Автор: Shah
Название: Cardiac Pacing and Defibrillation in Pediatric and Congenital Heart Disease
ISBN: 0470671092 ISBN-13(EAN): 9780470671092
Издательство: Wiley
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Цена: 16072.00 р. 22960.00 -30%
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Описание: With a growing population of young patients with congenital heart disease reaching adulthood, this unique new book offers an in-depth guide to managing the challenges and issues related to device therapy in this patient group.

Energy Metabolism in Insects

Автор: Roger G. H. Downer
Название: Energy Metabolism in Insects
ISBN: 1461592232 ISBN-13(EAN): 9781461592235
Издательство: Springer
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Цена: 15372.00 р.
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Описание: The scientific program for the XVI International Congress of Entomology, held in Kyoto, Japan August 3-9, 1980 included a symposium on the subject of "Energy Metabolism and Its Regulation in Insects." The symposium provided an opportunity to integrate knowledge, and focus attention, on an important and fundamental aspect of insect biochemis­ try/physiology. The energy metabolism of insects differs from that of other animals in a variety of ways, including the prodigious amounts of energy expended by flying insects, the presence in hemolymph of large concentrations of sugar in the form of the nonreducing disaccharide tre­ halose, the transport of fat in the form of diacylglycerol, and the periodic mobilization and deposition of cuticular components during development. These differences, together with hormones, neurohormones, and neu­ rotransmitters that are specific to (or functionally different in) insects, serve to demonstrate the unique nature of energy metabolism in insects. An obvious corollary from the demonstrated uniqueness of insect energy metabolism is that an understanding of the process may lead to the de­ velopment of new, specific agents or strategies for the suppression of insect pests. The present volume is an expanded version of the Kyoto symposium.

Cardiac Energy Metabolism in Health and Disease

Автор: Gary D. Lopaschuk; Naranjan S. Dhalla
Название: Cardiac Energy Metabolism in Health and Disease
ISBN: 1493912267 ISBN-13(EAN): 9781493912261
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Cardiac Energy Metabolism in Health and Disease

Cardiac Metabolism in Health and Disease

Автор: Salah Abdel-aleem; James E. Lowe
Название: Cardiac Metabolism in Health and Disease
ISBN: 0792381041 ISBN-13(EAN): 9780792381044
Издательство: Springer
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Цена: 38992.00 р.
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Описание: This special issue contains research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development.

Cardiac Output and Regional Flow in Health and Disease

Автор: A-M. Salmasi; A.S. Iskandrian
Название: Cardiac Output and Regional Flow in Health and Disease
ISBN: 0792319117 ISBN-13(EAN): 9780792319115
Издательство: Springer
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Цена: 62470.00 р.
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Описание: A useful reference on the topic of cardiac output. This book describes the methods of measuring cardiac output and a comparison between the catheterisation based and the noninvasive techniques. It also describes the changes in cardiac output due to physiological causes.

Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism

Автор: Aparajita Dey
Название: Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism
ISBN: 9400758804 ISBN-13(EAN): 9789400758803
Издательство: Springer
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Цена: 26122.00 р.
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Описание: The book examines clinical aspects of cytochrome P450 2E1(CYP2E1), covering clinical disorders associated with changes in the regulation of CYP2E1 and consequent abnormalities including alcoholic liver disease, hepatitis C, inhibition of bone repair and more.

Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease

Автор: Francisco Gonzalez-Lima
Название: Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease
ISBN: 0306460246 ISBN-13(EAN): 9780306460241
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Proceedings of an International Symposium held in New Orleans, Louisiana, October 28, 1997

Lipid Metabolism in the Healthy and Disease Heart

Автор: Ger J. van der Vusse; Hans Stam
Название: Lipid Metabolism in the Healthy and Disease Heart
ISBN: 1461365597 ISBN-13(EAN): 9781461365594
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands

Carbohydrates and Energy Metabolism

Автор: Alan A. Boulton; Glen B. Baker; Roger Butterworth
Название: Carbohydrates and Energy Metabolism
ISBN: 0896031438 ISBN-13(EAN): 9780896031432
Издательство: Springer
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Цена: 25853.00 р.
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Myocardial Energy Metabolism

Автор: J.W. de Jong
Название: Myocardial Energy Metabolism
ISBN: 9401070873 ISBN-13(EAN): 9789401070874
Издательство: Springer
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Цена: 12157.00 р.
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Mitochondrial Signaling in Health and Disease

Автор: Orrenius
Название: Mitochondrial Signaling in Health and Disease
ISBN: 1439880026 ISBN-13(EAN): 9781439880029
Издательство: Taylor&Francis
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Цена: 29093.00 р.
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Описание:

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.

With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:

  • Electron transport and energy production
  • Mitochondrial biogenesis and dynamics
  • Mitochondrial signaling
  • Apoptosis and autophagy
  • Pharmacology signaling
  • Epigenetic signaling: mitochondrial methylation and acetylation reactions

An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.

 

Noninvasive Imaging of Cardiac Metabolism

Автор: Ernst E. van der Wall
Название: Noninvasive Imaging of Cardiac Metabolism
ISBN: 9401079765 ISBN-13(EAN): 9789401079761
Издательство: Springer
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Цена: 12157.00 р.
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Описание: However, around 1980 pessimists predicted the premature demise of cardiovascular nuclear imaging with the introduction of digital subtraction angiography and nuclear magnetic resonance imaging.


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