Programmed Cells from Basic Neuroscience to Therapy, Fred H. Gage; Yves Christen

Автор: Haines Duane E.
Название: Fundamental Neuroscience for Basic and Clinical Applications
ISBN: 0323396321 ISBN-13(EAN): 9780323396325
Издательство: Elsevier Science
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Описание:

Using a rigorous yet clinically-focused approach, Fundamental Neuroscience for Basic and Clinical Applications, 5th Edition, covers the fundamental neuroscience information needed for coursework, exams, and beyond. It integrates neuroanatomy, pharmacology, and physiology, and offers a full section devoted to systems neurobiology, helping you comprehend and retain the complex material you need to know.

• Highlights clinical content in blue throughout the text, helping you focus on what you need to know in the clinical environment.

• Presents thoroughly updated information in every chapter, with an emphasis on new clinical thinking as related to the brain and systems neurobiology.
• Features hundreds of correlated state-of-the-art imaging examples, anatomical diagrams, and histology photos - nearly half are new or improved for this edition.
• Pays special attention to the correct use of clinical and anatomical terminology, and provides new clinical text and clinical-anatomical correlations.

Автор: S.I. Deutsch; A. Weizman; R. Weizman
Название: Application of Basic Neuroscience to Child Psychiatry
ISBN: 146127849X ISBN-13(EAN): 9781461278498
Издательство: Springer
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Цена: 12157.00 р.
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Описание: The idea for this book developed during the course of several discussions among the editors while we were working together as staff scientists in the laboratories of the Clinical Neuro- science Branch of the National Institute of Mental Health.

Автор: Young Paul A.
Название: Basic Clinical Neuroscience
ISBN: 1451173296 ISBN-13(EAN): 9781451173291
Издательство: Lippincott Williams & Wilkins
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Описание: Clinically oriented and student-friendly, this title provides the anatomic and pathophysiologic basis necessary to understand neurologic abnormalities. It emphasizes the localization of specific medically important anatomic structures and clinically important pathways, using anatomy-enhancing illustrations.

Автор: Hamsa Puthalakath; Christine J. Hawkins
Название: Programmed Cell Death
ISBN: 1493935798 ISBN-13(EAN): 9781493935796
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume containsprotocols specifically designed for studying programmed cell death, and alsodiscusses recent advances in techniques that span broader areas of biology thathave been recently used or that have potential to be incorporated into cell deathresearch.

Автор: Biller Jose
Название: Demyer`s the neurologic examination: a programmed text
ISBN: 0071701176 ISBN-13(EAN): 9780071701174
Издательство: McGraw-Hill
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Описание:

The classic step-by-step guide to learning how to perform the diagnostic neurologic examination - now in full color

"This is an excellent book that will be very useful for learning the neurologic examination. It is easy to read, well illustrated, and interactive. The art and science of neurology is constantly evolving and books must stay current with the available literature. This sixth edition provides updated information, illustrations, and references that are necessary to stay relevant to neurology today. 3 Stars."--"Doody's Review Service"

"Excellent. The information is detailed, pertinent, and excellently arranged. What is surprising is the incredibly complete, interesting, and worthwhile information it contains. The author is obviously an excellent clinician and teacher who has taught many years. One can easily detect that DeMyer's] book contains the distilled best of his teaching experiences."
--Archive of Internal Medicine*

"The book presents much more information than the title suggests; it has excellent parts on neuroanatomy and clinical neurosciences."
--Four Stars (Excellent) from Mayo Clinic Proceedings*

For more than four decades, "DeMyer's The Neurologic Examination" has provided neurologists and psychiatrists in training with a uniquely clear and didactic way of learning the complicated technique of using the physical examination to diagnose neurologic illness. This trusted classic also reviews the anatomy and physiology necessary to interpret the examination, and it details the laboratory tests best suited for a particular clinical problem.

Utilizing a proven-effective, learn-at-your-own-pace teaching approach, "DeMyer's" allows you to work through real-life clinical situations and rehearse the skills and procedures that make the neurologic examination productive for both patient and clinician. You will also learn how to tailor the exam for different clinical needs, including: The Unconscious Patient The Face and Head Vision The Peripheral Ocular Motor System The Central Ocular Motor System Cerebellar Dysfunction The Somatic Motor System The Special Senses

"DeMyer's The Neurologic Examination" features a new full-color presentation that includes the latest imaging modalities for assessing disease, questions and answers to help you monitor your progress, and content that reflects the knowledge and experience of outstanding teachers/clinicians.

Автор: Philip J. Farabaugh
Название: Programmed Alternative Reading of the Genetic Code
ISBN: 0412137518 ISBN-13(EAN): 9780412137518
Издательство: Springer
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Описание: 2. The Translational Machinery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Translation Initiation in Prokaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Translation Initiation in Eukaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 14 Translation Elongation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Translation Termination in Prokaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Translation Termination in Eukaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Error Correction in Translation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 A Structural Basis of Error Correction in Translation . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Ribosome Editing: A Failsafe Error Correction Mechanism . . . . . . . . . . . . . . . . 22 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 3. Errors During Elongation Can Cause Translational 29 Frameshifting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Spontaneous Frameshifting Versus Programmed Frameshifting . . . . . . . . . . 30 Spontaneous Frameshifts Can Be Induced at Specific Codons . . . . . . . . . . . . 31 4. Programmed +1 Frameshifting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 The pifE Gene of E. coli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Using the pifE System to Study General Frameshifting in E. coli . . . . . . . . 46 Ty Retrotransposons in Yeast . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Frameshifting in Retrotransposon Ty1 Occurs by tRNA Slippage . . . . . . . 48 Frameshifting in Retrotransposon Ty3 Occurs by Out-of-Frame Binding of tRNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 The Rat Ornithine Decarboxylase Antizyme Gene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 5. Programmed -1 Frameshifting in Eukaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 Programmed -1 Frameshifting in Eukaryotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 -1 Frameshifting Occurs on a "Slippery Heptamer" . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 The Simultaneous-Slippage Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 of -1 Frameshifting by a Downstream Pseudoknot . . . . . . . . . . 77 Stimulation Does the Pseudoknot Only Block Passage of the Ribosome? . . . . . . . . . .

Автор: John T. Corthell
Название: Basic Molecular Protocols in Neuroscience: Tips, Tricks, and Pitf
ISBN: 012801461X ISBN-13(EAN): 9780128014615
Издательство: Elsevier Science
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Описание:

Basic Neuroscience Protocols: Tips, Tricks, and Pitfalls contains explanatory sections that describe the techniques and what each technique really tells the researcher on a scientific level. These explanations describe relevant controls, troubleshooting, and reaction components for some of the most widely used neuroscience protocols that remain difficult for many neuroscientists to implement successfully. Having this additional information will help researchers ensure that their experiments work the first time, and will also minimize the time spent working on a technique only to discover that the problem was them, and not their materials.