Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide, Philip K. Moore; Matt Whiteman
Автор: Philip K. Moore; Matt Whiteman Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide ISBN: 3319181432 ISBN-13(EAN): 9783319181431 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.
Автор: Enrique Cadenas Название: Hydrogen Sulfide in Redox Biology Part A,554 ISBN: 0128015128 ISBN-13(EAN): 9780128015124 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant.
Автор: Hideo Kimura Название: Hydrogen Sulfide and its Therapeutic Applications ISBN: 370911974X ISBN-13(EAN): 9783709119747 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The metabolism of sulfur especially by sulfurtransferases had been intensively studied in mid 1900’s. Three enzymes, cystathionine ?–synthase (CBS), cystathionine ?–lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) were found to have the capacity to produce H2S in vitro. However, H2S was recognized simply as a by-product of the metabolic pathways or as a marker for evaluating the activity of enzymes rather than as a physiological active molecule. In the late 1980’s relatively high concentrations of sulfide were measured in the brain that led to the successive studies of identifying the physiological functions of H2S. Recently, the steady-state concentrations of H2S have been re-evaluated and found to be much less than that initially measured. However, despite these differences, such re-evaluations served to further confirm the existence of H2S in mammalian tissues. H2S is produced in almost every organ and plays various roles such as neuromodulation, vasodilation, insulin release, inflammation, angiogenesis and cytoprotection. The unregulated production of H2S and improper responses of target molecules are involved in the pathogenesis of various diseases. This book focuses on these topics as well as on the recent progress in the biology and the therapeutic development of this molecule.
Автор: Edgardo R. Donati; Wolfgang Sand Название: Microbial Processing of Metal Sulfides ISBN: 9048174023 ISBN-13(EAN): 9789048174027 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The application of microbiological methods to the extraction of metals from minerals is supported by several bioleaching and biooxidation processes operating in different sites over the world.
Автор: Fox P. F. Название: Dairy Chemistry and Biochemistry ISBN: 3319148915 ISBN-13(EAN): 9783319148915 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It also covers heat-induced changes in milk, the use of exogenous enzymes in dairy processing, principal physical properties of milk, bioactive compounds in milk and comparison of milk of different species.
Описание: This book is a comprehensive survey of all families of anticancer agents and therapeutic approaches. The book will acts as an indispensable resource for researchers, medicinal chemists and biomedical scientists. The new edition of this book will also have a Companion Website.
Автор: Bernd Nilius; Susan G. Amara; Thomas Gudermann; Re Название: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 163 ISBN: 3642444849 ISBN-13(EAN): 9783642444845 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading experts, this volume offers high-quality, in-depth reviews in the fields cardiovacular system, respiratory tract, channel physiology and TRPs
Автор: M. Briggs; A. Corbin Название: Progress in Hormone Biochemistry and Pharmacology ISBN: 9401177147 ISBN-13(EAN): 9789401177146 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: They include new religious movements - Falun Gong, Brahma Kumaris, the Hare Krishna movement, based in East and South Asia with outreach posts in Australia and the U.S. - and established `old` religions - Christianity, Buddhism, Hinduism and Islam - that are revitalized and recreated in different settings and places.
Автор: F. Wehner; H. Olsen; H. Tinel; E. Kinne-Safran; R. Название: Reviews of Physiology, Biochemistry and Pharmacology ISBN: 366231228X ISBN-13(EAN): 9783662312285 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: J.H. Exton; M.D. Lehner; T. Hartung; T. Sch?neberg Название: Reviews of Physiology, Biochemistry and Pharmacology ISBN: 3662310074 ISBN-13(EAN): 9783662310076 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.
Автор: R. H. Adrian; H. zur Hausen; E. Helmreich; H. Holz Название: Reviews of Physiology, Biochemistry and Pharmacology ISBN: 3662311305 ISBN-13(EAN): 9783662311301 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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