Автор: Fried Itzhak, Rutishauser Ueli, Cerf Moran Название: Single Neuron Studies of the Human Brain: Probing Cognition ISBN: 0262027208 ISBN-13(EAN): 9780262027205 Издательство: MIT Press Рейтинг: Цена: 11004.00 р. Наличие на складе: Нет в наличии.
Описание:
Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena.
In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field.
The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts.
Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rudiger Kohling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson
Автор: Boulis, Nicholas M Название: Molecular and Cellular Therapies for Motor Neuron Diseases ISBN: 0128022574 ISBN-13(EAN): 9780128022573 Издательство: Elsevier Science Рейтинг: Цена: 14654.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.
Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig's Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases
Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance
Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy
Автор: Nicholls John G Название: From Neuron to Brain 5e ISBN: 0878936092 ISBN-13(EAN): 9780878936090 Издательство: Oxford Academ Рейтинг: Цена: 19165.00 р. Наличие на складе: Поставка под заказ.
Описание: The entirely rewritten Fifth Edition of From Neuron to Brain describes how nerve cells go about their business of transmitting signals, how the signals are put together, and how, out of this integration, higher functions emerge. This exciting new edition begins with the anatomy and physiology of the visual system.
Автор: Jaime A. Pineda Название: Mirror Neuron Systems ISBN: 161737931X ISBN-13(EAN): 9781617379314 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thought-provoking and cutting-edge, this text lays down guidelines for future research in this fascinating and expanding field. It addresses issues common to different perspectives, raises contrary views, and creates the basis for an extended dialogue.
Автор: Suzumura Название: Neuron-Glia Interaction in Neuroinflammation ISBN: 1461483123 ISBN-13(EAN): 9781461483120 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Accumulation on glia is an active pathological element in many neurological disorders. The proposed book focuses on the interaction between neurons and glia to help elucidate the pathophysiology of neuroinflammation in neurological disorders.ГЇВїВЅ
Автор: L?der Deecke; John Eccles; Vernon B. Mountcastle Название: From Neuron to Action ISBN: 3662026031 ISBN-13(EAN): 9783662026038 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Their collected work combines fundamental research in the life sciences with clinical neuroscience in a unique overview. For example, oculomotor research, vestibular research, equilibrium, sensory research and cognition, evolution, synaptic and elementary processes and the neurological sciences can be discovered.
Автор: Bromberg, Mark Название: Motor Neuron Disease in Adults ISBN: 019978311X ISBN-13(EAN): 9780199783113 Издательство: Oxford Academ Рейтинг: Цена: 24948.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Motor Neuron Disease reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients.
Автор: Fiorenzo Battaini; Stefano Govoni; Maria S. Magnon Название: Regulatory Mechanisms of Neuron to Vessel Communication in the Brain ISBN: 3642741541 ISBN-13(EAN): 9783642741548 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Regulatory Mechanisms of Neuron to Vessel Communication in the Brain held in Salo, Italy, September 3-8, 1988
Автор: Akio Suzumura; Kazuhiro Ikenaka Название: Neuron-Glia Interaction in Neuroinflammation ISBN: 1493953648 ISBN-13(EAN): 9781493953646 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Accumulation of glia, gliosis, in various neurological disorders is not a static scar, but actively involved in pathogenesis of various neurological and psychiatric disorders, where glial cells produce both inflammatory and neurotrophic factors. These factors may play a role in neuronal damage, but also have a protective and reparative function by inducing neuroinflammation. However, definition as well as the mechanisms of neuroinflammation is not yet clear. We first define acute, chronic and non-classical neuroinflammation. Glial cells are activated by a variety of stimuli via receptors on glial cells. Toll like receptors (TLR) are one of these receptors. In response to harmful stimuli, neurons produce factors as either eat-me or help-me signals. These factors include cytokines, chemokines and damage-associated molecular pattern (DAMP). Some of them activate glial cells via TLR, and function to protect neurons or further induce neuroinflammation. Thus, the interaction between neuron-glia and glia-glia is a main feature of neuroinflammation. Glial cells communicate with other glial or neural cells via gap-junctions. The communication may also be important for the understanding of neuroinflammation. Oligodendrocytes-neurons communication may be critical in either myelination or demyelination. Damage of blood-brain barrier (BBB) is common feature of both inflammatory and degenerative neurological disorders. Thus, relation of BBB damage and functions of glial cell may also be important in the development of neuroinflammation. In this book, we focused on neuron-glia interaction of various aspects for understanding of pathophysiology of neuroinflammation in development of inflammatory as well as degenerative neurological disorders.
Автор: Antonia Vernadakis; Betty I. Roots Название: Neuron—Glia Interrelations During Phylogeny ISBN: 0896033163 ISBN-13(EAN): 9780896033160 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One volume in a two-part series, covering the physiological and metabolic interactions between neurons and glia across the phylogenetic groups. New insights into neuron-glia relationships result from this comparative approach.
Автор: P.N. Leigh; Michael Swash Название: Motor Neuron Disease ISBN: 1447118731 ISBN-13(EAN): 9781447118732 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND).
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