Male-Mediated Developmental Toxicity, Andrew F. Olshan; Donald R. Mattison

Автор: Andrew F. Olshan; Donald R. Mattison
Название: Male-Mediated Developmental Toxicity
ISBN: 1461357640 ISBN-13(EAN): 9781461357643
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Proceedings of an international conference held in Pittsburgh, Pennsylvania, September 16-19, 1992

Автор: Benjamin Bonavida; Salem Chouaib
Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy
ISBN: 3319178067 ISBN-13(EAN): 9783319178066
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

Автор: P. Cuatrecasas; T.F. Roth
Название: Receptor-Mediated Endocytosis
ISBN: 940095977X ISBN-13(EAN): 9789400959774
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This volume focuses exclusively on those endocytic processes that sequester proteins by a selective, receptor-mediated mechanism. The hallmarks of ,this process are the specific receptors, coated pits, coated vesicles and an ordered sequence of transit events leading to delivery to selected locations.

Автор: Craig Harris; Jason M. Hansen
Название: Developmental Toxicology
ISBN: 1493962078 ISBN-13(EAN): 9781493962075
Издательство: Springer
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Цена: 20263.00 р.
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Описание: This book details methods used to study developmental toxicology. It highlights the evolution of methods from classical teratology approaches to dynamic, state-of-the-art molecular methods, systems biology, and next generation models and procedures.

Автор: Ali S. Faqi
Название: Developmental and Reproductive Toxicology
ISBN: 1493972065 ISBN-13(EAN): 9781493972067
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands.