Technologies for Detection of DNA Damage and Mutations, G.P. Pfeifer

Автор: Graham R. Taylor
Название: Guide to Mutation Detection
ISBN: 0471234443 ISBN-13(EAN): 9780471234449
Издательство: Wiley
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Описание: As genomic science and potential gene therapies continue to develop, the detection of mutations plays an increasingly central role in diverse areas of biology. With innumerable detection techniques available spanning multiple disciplines, the choice of the best method for a particular study can prove exceedingly difficult.

Автор: G.P. Pfeifer
Название: Technologies for Detection of DNA Damage and Mutations
ISBN: 1489903038 ISBN-13(EAN): 9781489903037
Издательство: Springer
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Описание: Man-made carcinogens, natural genotoxic agents in the environment, as well as ionizing and ultraviolet radiation can damage DNA and are a constant threat to genome integrity.

Автор: Keshav K. Singh
Название: Mitochondrial DNA Mutations in Aging, Disease and Cancer
ISBN: 3662125110 ISBN-13(EAN): 9783662125113
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson`s, Alzheimer`s, and Huntington`s diseases.

Автор: G. Obe
Название: Mutations in Man
ISBN: 3642695329 ISBN-13(EAN): 9783642695322
Издательство: Springer
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Цена: 15372.00 р.
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Описание: In no case has it been shown unequivocally that physical or chemical mutagens have led to an elevation of the mutation rate in the germ cells of man, but in view of the huge body of experi- mental data this seems to be a problem of detection.

Автор: S.M. Jain; D.S. Brar; B.S. Ahloowalia
Название: Somaclonal Variation and Induced Mutations in Crop Improvement
ISBN: 0792348621 ISBN-13(EAN): 9780792348627
Издательство: Springer
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Описание: Describes the relative value of each method of improving various agricultural crops by using parasexual techniques. This book highlights the developments in mutagenesis (conventional approach and molecular biology) and in vitro induced variation in plant breeding.

Автор: Ismail Adeniran
Название: Modelling the Short QT Syndrome Gene Mutations
ISBN: 3319361511 ISBN-13(EAN): 9783319361512
Издательство: Springer
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Описание: The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death.

Автор: Donald A. Dawson; Andreas Greven
Название: Spatial Fleming-Viot Models with Selection and Mutation
ISBN: 3319021524 ISBN-13(EAN): 9783319021522
Издательство: Springer
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Цена: 6986.00 р.
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Описание:

Introduction.- Emergence and fixation in the F-W model with two types.- Formulation of the multitype and multiscale model.- Formulation of the main results in the general case.- A Basic Tool: Dual Representations.- Long-time behaviour: ergodicity and non-ergodicity.- Mean-field emergence and fixation of rare mutants (Phase 1,2).- Methods and proofs for the F-W model with two types.- Emergence, fixation with M >= 2 lower order types.- Emergence, fixation: The general (M, M)-type mean-field model.- Neutral evolution on E₁ after fixation (Phase 3).- Re-equilibration on higher level E₁ (Phase 4).- Iteration of the cycle I: Emergence and fixation on E₂.- Iteration of the cycle - the general multilevel hierarchy.- Winding-up: Proofs of the Theorems 3-11.- Appendix 1 - Tightness.- Appendix 2. Nonlinear semigroup perturbations.- References.- Index of Notation and Tables of Basic Objects.- Index.

Автор: Ronny C. Woodruff; James N. Thompson
Название: Mutation and Evolution
ISBN: 9401061939 ISBN-13(EAN): 9789401061933
Издательство: Springer
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Описание: From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability.

Автор: Banoub, Joseph.
Название: Molecular technologies for detection of chemical and biological agents /
ISBN: 9402411127 ISBN-13(EAN): 9789402411126
Издательство: Springer
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Описание:

This book describes the latest molecular insights needed to understand the chemical and biological (CB) agents and their associated biotechnologies. Its primary focus is to present and discuss molecular technologies such as mass spectrometry, chemical and biological sensors, chromatographic and electrophoretic separation, and comparisons of spectroscopic, immunological and molecular analyses of chemicals used for the detection of chemical and biological agents and to prevent terrorism.