Описание: This book reviews current progress on heat shock proteins in the brain and their implications for neurodegenerative diseases, neuroprotection, aging and control of life span. It features contributions from laboratories from major universities around the world.
Описание: Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships.
Автор: Baekelandt, Veerle Название: Disease-Modifying Targets in Neurodegenerative Disorders ISBN: 0128051205 ISBN-13(EAN): 9780128051207 Издательство: Elsevier Science Рейтинг: Цена: 11706.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies.
This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.
Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress
Summarizes how patients are treated today, providing a glance at future disease management
Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists
Written and peer reviewed by outstanding scientists in their respective fields
Описание: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases. The book is packaged with a password, giving the user online access to all the text and images.
Описание: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret.
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