Intermediate Filaments, Harald Herrmann; J. Robin Harris

Автор: P. Traub
Название: Intermediate Filaments
ISBN: 3642702325 ISBN-13(EAN): 9783642702327
Издательство: Springer
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Описание: The investigation of cultured cells and of tissues from various developmental stages has furnished a host of information on the inter-and intracellular distribution of the different types of intermediate filaments and led to the contention that they have a structural and organizing function in the cytoplasm of vertebrate cells.

Автор: R.D. Goldman; P.M. Steinert
Название: Cellular and Molecular Biology of Intermediate Filaments
ISBN: 0306433176 ISBN-13(EAN): 9780306433177
Издательство: Springer
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Описание: Research activity on intermediate filaments (IF) has increased dramatically over the past decade. For the most part, this surge of interest is due to their identification as ubiquitous constituents of the cytoskeleton and karyoskeleton (nuclear matrix) of eukaryotic cells and the fact that we know very little regarding their functions. In sharp contrast to the other major cytoskeletal systems, microfilaments and microtubules, IF exhibit a high degree of heterogeneity with regard to their protein subunit composition. Indeed, one can only marvel at the number of different IF polypeptides, their associated proteins (IFAP) and, consequently, the number of genes involved in encoding the multiple constituents of the various IF networks found in different cell types. The chapters in this book demonstrate how various experimental approaches involv- ing cellular, molecular, biochemical, and immunological methods have been utilized to generate information regarding the structure and function of IF. To this end, we have gathered together chapters from experts in the major fields of IF research. In each chapter, the authors have combined reviews of the available scientific literature with their own ideas on current and future directions for IF research. The chapters have been divided into five major sections which are concerned with the subcellular organization of IF, the molecular structure of IF, the differential expression of IF genes, descriptions of associ- ated proteins involved in the intracellular organization of IF, and finally an analysis of the changes seen in IF in pathological conditions.

Автор: R.D. Goldman; P.M. Steinert
Название: Cellular and Molecular Biology of Intermediate Filaments
ISBN: 1475796064 ISBN-13(EAN): 9781475796063
Издательство: Springer
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Автор: H.L. Granzier; Gerald H. Pollack
Название: Elastic Filaments of the Cell
ISBN: 1461369169 ISBN-13(EAN): 9781461369165
Издательство: Springer
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Описание: Elastic filaments refer mainly to titin, the largest of all known proteins. Titin forms a molecular spring that is responsible for maintaining the structural integrity of contracting muscle, ensuring efficient muscle contraction. More recently, it has become clear that titin is not restricted to muscle cells alone.

Автор: Katherine L. Wilson
Название: Intermediate Filament Associated Proteins,569
ISBN: 0128034696 ISBN-13(EAN): 9780128034699
Издательство: Elsevier Science
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Описание: Intermediate Filament Associated Proteins, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in intermediate filament associated proteins and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers.

Автор: Haruo Sugi
Название: Sliding Filament Mechanism in Muscle Contraction
ISBN: 1441937668 ISBN-13(EAN): 9781441937667
Издательство: Springer
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Описание: Sliding Filament Mechanism in Muscle Contraction: Fifty Years of Research covers the history of the sliding filament mechanism in muscle contraction from its discovery in 1954 by H.E.

Автор: M Bishr Omary
Название: Intermediate Filament Proteins,568
ISBN: 012803470X ISBN-13(EAN): 9780128034705
Издательство: Elsevier Science
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Описание:

Intermediate Filament Proteins, the latest volume in the Methods in Enzymology series covers all the intermediate filaments in vertebrates and invertebrates, providing a unique understanding of the multiple different tissue-specific intermediate filaments.