The Molecules Within US, Charles A. Pasternak

Автор: Bernard Robaire; Barry Hinton
Название: The Epididymis: From Molecules to Clinical Practice
ISBN: 146135191X ISBN-13(EAN): 9781461351917
Издательство: Springer
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Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Since the late 1960s, there has been an acceleration of research focused on understanding how the efferent ducts, the epididymis, and the vas deferens function with respect to the maturation and storage of spermatozoa and as hormone dependent tissues.

Автор: Kenneth Maiese
Название: Molecules to Medicine with mTOR
ISBN: 0128027339 ISBN-13(EAN): 9780128027332
Издательство: Elsevier Science
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Цена: 15999.00 р.
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Описание: Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin.

• Covers the role of mTOR by internationally recognized expert contributors in the field.
• Provides a clear picture of the complexity of mTOR signaling as well as of the different approaches that could target this pathway at various levels.
• Includes analysis of the role of mTOR and in both health and disease.
• Serves as an important resource for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings.