Автор: Abbas, Abul K. Fausto, Nelson Kumar, Vinay Название: Robbins and Cotran Pathologic Basis of Disease.-9 ed. ISBN: 0808924508 ISBN-13(EAN): 9780808924500 Издательство: Elsevier Science Рейтинг: Цена: 9136.00 р. Наличие на складе: Поставка под заказ.
Описание: Ashton B. Carter said when announcing that the Pentagon would open all combat jobs to women, "I made a commitment to building America`s force of the future. In the twenty-first century, that requires drawing strength from the broadest possible pool of talent." William Taylor chronicles and analyses the long and ever-changing history of that often contentious and controversial effort.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Justin C. St. John Название: Mitochondrial DNA, Mitochondria, Disease and Stem Cells ISBN: 1627038671 ISBN-13(EAN): 9781627038676 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process.
Описание: Complemented by: Robbins and Cotran pathologic basis of disease / [edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster. Ninth edition. [2015].
Автор: Shuiping Jiang Название: TH17 Cells in Health and Disease ISBN: 1489997342 ISBN-13(EAN): 9781489997340 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: TH17 cells are an independent subset of T cells with specific functions in eliminating extracellular pathogens not adequately handled by TH1 or TH2 cells. A better understanding of them will have wide implications for a variety of therapeutic strategies.
Автор: Michail Ignatiadis; Christos Sotiriou; Klaus Pante Название: Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer ISBN: 364244587X ISBN-13(EAN): 9783642445873 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.
Автор: E. Reid; G.M.W. Cooke; J.P. Luzio Название: Cells, Membranes, and Disease, Including Renal ISBN: 146841285X ISBN-13(EAN): 9781468412857 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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