Triple-Helical Nucleic Acids, Valery N. Soyfer; Vladimir N. Potaman

Автор: Hiromi Yamakawa; Takenao Yoshizaki
Название: Helical Wormlike Chains in Polymer Solutions
ISBN: 3662487144 ISBN-13(EAN): 9783662487143
Издательство: Springer
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Описание: This book presents the "helical wormlike chain" model - a general model for both flexible and semiflexible polymer chains. It explains how statistical-mechanical, hydrodynamic, and dynamic theories of their solution properties can be developed on the basis of this model. This new second edition has been carefully updated and thoroughly revised. It includes a new chapter covering "Simulation and More on Excluded-Volume Effects", as well as the discussion of new experimental data and the application of the theory to ring polymers.
The authors provide analysis of important recent experimental data by the use of their theories for flexible polymers over a wide range of molecular weights, including the oligomer region, and for semiflexible polymers, including biological macromolecules such as DNA. This is all clearly illustrated using a reasonable number of theoretical equations, tables, figures, and computer-aided forms, which support the understanding of the basic theory and help to facilitate its application to experimental data for the polymer molecular characterization.

Автор: N. Kochetkov
Название: Organic Chemistry of Nucleic Acids
ISBN: 147570545X ISBN-13(EAN): 9781475705454
Издательство: Springer
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Описание: The study of nucleic acids is one of the most rapidly developing fields in modern science. There is yet another highly important aspect of the chemistry of nucleic acids which is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components.

Автор: Christopher Janson; Matthew During
Название: Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules
ISBN: 1489986448 ISBN-13(EAN): 9781489986443
Издательство: Springer
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Описание: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications.

Автор: Yingfu Li; Yi Lu
Название: Functional Nucleic Acids for Analytical Applications
ISBN: 1441925309 ISBN-13(EAN): 9781441925305
Издательство: Springer
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Описание: This book is a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. Topics range from fundamentals of functional nucleic acids, to their applications as sensors, and nanotechnologies.

Название: Modified nucleic acids
ISBN: 3319271091 ISBN-13(EAN): 9783319271095
Издательство: Springer
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Описание: Emissive 5-Substituted Uridine Analogues.- Fluorescent purine nucleosides and their applications.- Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids.- Synthetic wavelength-shifting fluorescent probes of nucleic acids.- DNA Assisted Multichromophore Assembly.- Polymerase Synthesis of Base-Modified DNA.- Photo-cross-linking Reaction in Nucleic Acids - Chemistry and Applications.- Site-Directed Spin Labeling for EPR Studies of Nucleic Acids.- Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site.- 2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA.- Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine.- Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.

Автор: O. J. Plescia; W. Braun
Название: Nucleic Acids in Immunology
ISBN: 3642876706 ISBN-13(EAN): 9783642876707
Издательство: Springer
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Цена: 16979.00 р.
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Описание: New experi- mental approaches brought the realization that nucleic acids, under appropriate conditions, are indeed immunogenic, and that the resulting antibodies can furnish new tools for the exploration of the mplecular structure of the all-important family of nucleic acid molecules.