Описание: In recent years, the ATP synthase (H+-ATPase, FoFrATPase) has been the subject of intensive IDvestigations in many laboratories. The major reason for this lies in the fact that this enzyme complex catalyses one of the most important reactions in living cells, namely the synthesis of ATP utilizing the energy from an electrochemical transmembrane H+ gradient, generated by the cellular respiratory chain or by the light reactions of photosynthetic organisms. The mechanism by which the H+ motive force is utilized to drive the synthesis of ATP is one of the major unsolved problems in biochemistry. Thus, the fundamental information concerning the-molecular structure and the mechanism of assembly of the ATP synthase is of major significance in cell biology. A seminar/workshop on the Molecular Structure, Function and Assembly of the ATP synthases was held in April, 1987 at the East-West Center, University of Hawaii, Honolulu, Hawaii, to promote exchange of information between laboratories actively engaged in the study of the A TP synthases, and to provide a forum for discussion and coordination of data derived from molecular, genetic and biochemical approaches used in different laboratories. This volume summarizes the result of the seminar/workshop, in the form of a collection of papers presented at the meeting, and provides an overvIew of current work in this rapidly progressing area of research.
Автор: Paul-Andr? Siegenthaler; N. Murata Название: Lipids in Photosynthesis: Structure, Function and Genetics ISBN: 0792351738 ISBN-13(EAN): 9780792351733 Издательство: Springer Рейтинг: Цена: 41787.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides readers with a view of the structure, function and genetics of lipids in plants, algae and bacteria, with emphasis on the photosynthetic apparatus in thylakoid membranes. This volume includes the historical background of the field, as well as a full review of our understanding of the structure and molecular organization of lipids.
Автор: David Whitford Название: Proteins: Structure and Function ISBN: 0471498947 ISBN-13(EAN): 9780471498940 Издательство: Wiley Рейтинг: Цена: 8546.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: * An accessible introduction to the principles of protein structure and function. * Beautifully illustrated throughout in full colour. * Includes end of chapter problems, references to further reading and a full glossary of terms. * Associated website including web-based tutorials, problems and additional content. .
Описание: A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development and continued well-being and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. VOLUME I: Here, we present the first volume of a multi-volume series on Retinoic Acid Signaling that will cover all aspects of this broad and diverse field. One aim of Volume I is to present a compilation of topics related to the biochemistry of nuclear retinoic acid receptors, from their architecture when bound to DNA and associated with their coregulators to their ability to regulate target gene transcription. A second aim is to provide insight into recent advances that have been made in identifying novel targets and non-genomic effects of retinoic acid. Volume I is divided into ten chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.
Автор: Craig Nancy Название: Molecular Biology Principles of Genome Function ISBN: 0199658579 ISBN-13(EAN): 9780199658572 Издательство: Oxford Academ Рейтинг: Цена: 9186.00 р. Наличие на складе: Поставка под заказ.
Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.
Автор: Greta Pifat-Mrzljak Название: Supramolecular Structure and Function ISBN: 3642709079 ISBN-13(EAN): 9783642709074 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: During the past decade we have witnessed not only an increase in knowledge of the "traditional" biophysical problems, but also an understanding of the molecular basis of various biological phenomena.
Автор: Wolfgang Hennig Название: Structure and Function of Eukaryotic Chromosomes ISBN: 3662224380 ISBN-13(EAN): 9783662224380 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents an overview of various aspects of chromosome research, written by leading experts of the respective fields, combining classic and recent molecular biological results. The variety and comprehensiveness make it a handbook of chromosome research for all scientists, teachers and graduate students interested in this field. Dieses Buch fa?t die unterschiedlichen Aspekte der Chromosomenforschung in Beitr?gen von f?hrenden Wissenschaftlern zusammen, wobei die klassischen Erkenntnisse mit neuesten Forschungsdaten zu einem umfassenden ?berblick ?ber das Gebiet kombiniert werden.
Автор: J.V. Bannister Название: Structure and Function of Haemocyanin ISBN: 3642666817 ISBN-13(EAN): 9783642666810 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Haemocyanin was first recognised as a respiratory pigment by P. Bert in 1867. Over the years the haemocyanins have attracted attention as macromolecules and copper-contain- ing respiratory proteins. The early functional studies of A.C. Redfield (Biol. Rev. 9, 176, 1934) and the ultracen- trifuge work of I.B. Ericksson-Quensel and T. Svedberg (Biol. Bull. 21, 498, 1936) come easily to mind. In recent years haemocyanin studies have come to the forefront with the work of the Ghirettis (Padova), R. Lontie (Louven), E.F.J. Van Bruggen (Groningen) and Joe and Celia Bonaven- tura (Beaufort) to mention but a few of the number of able investigators coming to this field from diverse disciplines. It is hoped that this book presents a fair cross section of current workers and work on haemocyanin. It is the sec- ond collection of haemocyanin studies to be published after a Workshop on the Structure and Function of Haemocyanin. The first haemocyanin meeting was held by Professors F. "Ghiro" Ghiretti and Anna Ghiretti-Magaldi in Naples in 1966. Subsequent meetings have been held at Groningen (1970), Louven (1971) and Padova (1974). Current interest in haemocyanin can be judged by the scope and breadth of the papers from the Malta meeting and pre- sented here. In organising the Malta meeting I would like to thank Dr. John Tooze of the European Molecular Biology Organisation and my friend and colleague, Professor Mauri- zio Brunori for their continuous help and support.
Автор: Francesco Bossa Название: Structure and Function Relationships in Biochemical Systems ISBN: 1461592836 ISBN-13(EAN): 9781461592839 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Studies on the elucidation of structure-function relationships in biochemistry and molecular biology started a few decades ago and represent an area of continuing interest. The celebration of the 75th birthday of Alessandro Rossi Fanelli, who has made signi- cant contributions in this field, prompted the organization of a Symposium on 'Structure-Function Relationships in Biochemical Systems' with the aim of bringing together Rossi Fanelli's students and many of the scientists who have been connected with the Institute of Biological Chemistry in Rome. The Symposium was held in Rome on September 28-30, 1981 at the Accademia Nazionale dei Lincei. This volume contains the lectures presented at the Symposium as well as articles covering the main themes of research conducted in Rossi-Fanelli's Institute. The material is divided into five sections: Hemoglobin, Myoglobin and Other Respiratory Proteins; Mechanism of Action of Metal-Containing Enzym s; Bioenergetics, Mem- brane Structure and Multienzyme Complexes; Cofactor-Dependent En- zymes; Sulfur Metabolism. We gratefully acknow edge the generous financial support of the Italian National Research Council and of the University of Rome, which rendered the Symposium possible. We wish to thank all the con- tributors and Maurizio Gattoni, Paolo Gerosa and Mario Sanchioni for their help in the preparation of the illustrative material. Fi- nally we wish to express our gratitude to Professor Rossi Fanelli, the unfailing animator of our Institute; in his honour we happily undertook the task of editing this volume.
Автор: Hieronim Jakubowski Название: Homocysteine in Protein Structure/Function and Human Disease ISBN: 3709117208 ISBN-13(EAN): 9783709117200 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Excess of homocysteine, a product of the metabolism of the essential amino acid methionine, is associated with poor health, is linked to heart and brain diseases in general human populations, and accelerates mortality in heart disease patients. Neurological and cardiovascular abnormalities occur in patients with severe genetic hyperhomocysteinemia and lead to premature death due to vascular complications. Although it is considered a non-protein amino acid, studies over the past dozen years have discovered mechanisms by which homocysteine becomes a component of proteins. Homocysteine-containing proteins lose their normal biological function and become auto-immunogenic and pro-thrombotic. In this book, the author, a pioneer and a leading contributor to the field, describes up-to date studies of the biological chemistry of homocysteine-containing proteins, as well as pathological consequences and clinical implications of their formation. This is a comprehensive account of the broad range of basic science and medical implications of homocysteine-containing proteins for health and disease.
Описание: Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field.
Описание: Proceedings of the Second International Conference: "Structure and Function of Molecules Involved in Leucocyte Adhesion II", Held in Titisee, Germany, October 2-6, 1991
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