Molecular Components of Hepatitis B Virus, M. Feitelson
Автор: Miyamura Название: Hepatitis C Virus I ISBN: 4431560963 ISBN-13(EAN): 9784431560968 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is composed of chapters that review important fundamental aspects of HCV biology and disease pathogenesis including, for example, the discovery and identification of the HCV genome, early virus-cell interactions including identification of various cellular receptors, HCV gene expression studied using the HCV replicon system, identification and characterization of HCV structural- and non-structural HCV proteins, HCV replication in cultured cells, and host factors involved in viral replication. This volume also contains chapters dealing with immunity to HCV infection and pathogenesis. This is particularly important in understanding hepatitis C because HCV infection alone is not cell lytic. Mechanisms underlying the persistent nature of HCV infection are also discussed in these chapters. Many of the authors published articles that were listed among the “top 10 papers” published in the 24 years since HCV was discovered in 1989. Their citations are above 1,000 (Web of Science). The authors describe the background and significance of their contributions to the field in the context of findings from other research groups.
Автор: Tatsuo Miyamura; Stanley M. Lemon; Christopher M. Название: Hepatitis C Virus II ISBN: 4431560998 ISBN-13(EAN): 9784431560999 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book helps scientists, clinicians and otherinterested individuals understand recent clinical advances and challenges forthe future. It covers many basic aspects of the pathogenesis of chronic hepatitisC, HCV infections in particular populations, approaches to therapy, andprevention and control of HCV Infection. The book provides a succinct review ofthe large amount of data generated by multiple groups over the past two decadesthat has revealed the natural history of HCV infection. Similarly, itsummarizes current understanding of the origins of HCV-associatedhepatocellular carcinoma, cirrhosis and hepatic fibrosis. Extra-hepaticmanifestation and metabolic disorders related to HCV infection are described.In this volume, these clinically important aspects of HCV infection arecomprehensively described. Highlights are description of newly developed direct- acting antivirals. The authors represent a worldwidedistribution of leaders in the field reflecting the global nature of HCVinfection. Based on recent data concerning the genetic- and geographicaldiversity of HCV, and increased global disease burden of HCV infection, challenges for global control of HCV infections are described.
Описание: Innate immunity in Type C Hepatitis.- Mechanisms of Interferon Action and Resistance: Lessons learned from cell cultures studies.- Immunological Parameters Determining the Outcome of Hepatitis C Virus Infection.- The Effects of Interferon-Alpha Therapy on Immune Response and Outcome.- Microbial Components Associated with HCV Disease Interfere with Response to Interferon-alpha/Ribavarin Treatment.- IFN-induced Effector Proteins and HCV Replication.- Treatment of Chronic Hepatitis C with Various Genotypes.- IFNs in HCV infection: Biological and Clinical Considerations.- Clinical application of IFN-based therapy for HCV.- HCV therapy in difficult-to-treat patients.- Effects of IFN-alpha/Ribavirin Treatment on HCV Disease and Related Progression.
Автор: M. Feitelson Название: Molecular Components of Hepatitis B Virus ISBN: 1461296153 ISBN-13(EAN): 9781461296157 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the discovery of Australia antigen and its association with type B hepatitis, molecular characterization of the components making up hepatitis B virus (RBV) have been pursued with worldwide interest.
Автор: Kamal, Sanaa M. Название: Hepatitis C in Developing Countries ISBN: 0128032332 ISBN-13(EAN): 9780128032336 Издательство: Elsevier Science Рейтинг: Цена: 13298.00 р. Наличие на складе: Поставка под заказ.
Описание:
Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.
Features coverage on the prevention of, or inhibition of, liver fibrosis, cirrhosis, and hepatocellular carcinoma
Presents data from trials on patients with diverse ethnic backgrounds and those infected with genotypes 3, 4, 5, 6
Addresses the epidemiology, modes of transmission, socio-political aspects, genotypes, and co-infections of Hepatitis C
Автор: Ralf Bartenschlager Название: Hepatitis C Virus: From Molecular Virology to Antiviral Therapy ISBN: 364242936X ISBN-13(EAN): 9783642429361 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected.
Автор: Emilio Jirillo Название: Hepatitis C Virus Disease ISBN: 1441924388 ISBN-13(EAN): 9781441924384 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite numerous hepatitis C virus infection studies, its pathogenesis and medical treatment have not been fully explained. This comprehensive volume, written by experts in the field, covers the most recent advances in the study of HCV, moving from basic research to clinical applications.
Автор: C.H. Hagedorn; C.M. Rice Название: The Hepatitis C Viruses ISBN: 3642640478 ISBN-13(EAN): 9783642640476 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chronic hepatitis C is a major worldwide health problem affecting more than 170 million people. This volume includes comprehensive reviews that cover much of the vast literature that has appeared since the identification of the hepatitis C virus RNA genome.
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