The Differentiation of Rat Ova During Cleavage, J. Stastna; Milan Dvorak; S. Cech; P. Travnik; D.
Автор: Jean-Pierre Tassan; Jacek Z. Kubiak Название: Asymmetric Cell Division in Development, Differentiation and Cancer ISBN: 3319531492 ISBN-13(EAN): 9783319531496 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.
Описание: Understanding stem cell differentiation is a key step on the road to unlocking the cells` therapeutic potential. This book shows how microenvironmental factors regulate the differentiation and assembly of stem cells that develop into functional vasculature.
Автор: Arnold A. Gerall; Howard Moltz; Ingeborg L. Ward Название: Sexual Differentiation ISBN: 1489924558 ISBN-13(EAN): 9781489924551 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Based on a large variety of experiments on both humans and animals, this volume presents novel conceptualizations of the organizing consequences of hormones throughout the lifespans of mammals.
Описание: How do males become male and females become female? The genetic determination of sex and how sexual organs are differentiated are described in this 1995 book. The molecular basis of sex is explained, referring to intersexuality, chimaeras and asymmetries. Highly interesting for reproductive physiologists and geneticists.
Автор: Lugli Название: T-Cell Differentiation ISBN: 1493965468 ISBN-13(EAN): 9781493965465 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides protocols to successfully apply cutting-edge technologies to characterize the biology of T cells at an unprecedented level of complexity. Chapters guide readers through flow cytometry and fluorescence-activated cell sorting, the behaviour of single T cells after adoptive cell transfer (ACT), single cell gene expression by multiplex PCR, lentiviral transduction approaches, protocols to derive large numbers of early-differentiated memory T cells by using dedicated cytokines cocktails, approaches to measure telomerase activity in terminally differentiated T cells, and approaches to define Treg cells at the phenotypic and functional level. The final part of the book is dedicated to the analysis of the differentiation and effector functions of innate T cells, namely the well-known ?/? T cells, and the recently identified CD8+ mucosal associated invariant T (MAIT) cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Differentiation: Methods and Protocols aims to provide protocols that are fundamental to monitor the T cell compartment at the level of single cells in pathological and immunotherapy conditions.
Автор: Volker Schurig Название: Differentiation of Enantiomers I ISBN: 3319032380 ISBN-13(EAN): 9783319032382 Издательство: Springer Рейтинг: Цена: 39182.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research.
Автор: Jean-Pierre Saint-Jeannet Название: Neural Crest Induction and Differentiation ISBN: 1461497612 ISBN-13(EAN): 9781461497615 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.
Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
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