The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies, D.L. Arnold; H.C. Grice

Автор: H.C. Grice
Название: Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards
ISBN: 3540136967 ISBN-13(EAN): 9783540136965
Издательство: Springer
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Описание: The International Life Sciences Institute (lLSI) is a scientific foundation wh ich addresses critical health and safety issues of national and international concern.

Автор: Micheline Kirsch-Volders
Название: Mutagenicity, Carcinogenicity, and Teratogenicity of Industrial Pollutants
ISBN: 1461296498 ISBN-13(EAN): 9781461296492
Издательство: Springer
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Описание: An introductory chapter deals with the mechanisms whereby a given compound, reaching genetic material, either directly or indirectly, may increase the risk of a cancer developing in the exposed individual and of abnormalities being passed on to his or her progeny.

Автор: J. Venitz; W. Sittner
Название: Appropriate Dose Selection - How to Optimize Clinical Drug Development
ISBN: 3642421768 ISBN-13(EAN): 9783642421761
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Optimal dose individualization has become more important in improving clinical efficacy and safety. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized.