Lymphoid Organogenesis, Fritz Melchers

Автор: Fritz Melchers
Название: Lymphoid Organogenesis
ISBN: 364263186X ISBN-13(EAN): 9783642631863
Издательство: Springer
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Описание: It has been clear for a long time that after transplantation of a lymphoid organ, hematopoietic stem cells can regenerate the compartments of the organ, provided that the rest of its architecture - the strome, the epithelia and the vessels - is intact.

Автор: Peter Balogh
Название: Developmental Biology of Peripheral Lymphoid Organs
ISBN: 3642444318 ISBN-13(EAN): 9783642444319
Издательство: Springer
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Описание: A comprehensive overview of the way in which the major peripheral lymphoid organs grow and change over time enables this book to take a developmental approach in examining the connection between their immunological functionality and structural characteristics.

Автор: G. Klaus
Название: Microenvironments in the Lymphoid System
ISBN: 1461294959 ISBN-13(EAN): 9781461294955
Издательство: Springer
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Описание: Since 1966, at ro ghly three-yearly intervals, an internation- al group of immunologists has met somewhere in Europe to discuss the latest developments in our understanding of the mechanisms governing the functioning of the immune system in vivo. These meetings have become known as the International C, mferences on Lymphatic Tissues and Germinal Centers in Immune Reactions, or for the regular devotees, simply as the Germinal Cent' r Conferences (GCC). This volume represents the proceedings of the 8th GCC, which was held in Babraham, near Cambridge, UK, between the 14th and 17th August, 1984. When one considers how cellular immunology has become increas- ingly dominated by in vitro methodology over the past twenty years, it may seem remarkable that these conferences-hav survived at all, let alone prospered. However, I for one do not find this surprising, since I suspect that the exquisitely: omplex architect- ure and microenvironments of the lymphoid system will never be fully understood through in vitro studies. If "tae proper study of mankind is an", then surely ultimately the proper study of all the interacting elements which comprise the immune system has to be in vivo. This belief is shared by a substantial number of immunol- ogists, as the contents of this volume will attest. Although the GCC were originally devoted to unravelling the mysteries of the germinal center response (and these are still not fully resolved), over the years the scope of the meetings has inevitably broadened.

Автор: Tasuku Honjo; Fritz Melchers
Название: Gut-Associated Lymphoid Tissues
ISBN: 3642067948 ISBN-13(EAN): 9783642067945
Издательство: Springer
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Описание: Preface.- Role of the Innate Immune System and Host-Commensal Mutualism.- Molecular Networks Orchestrating GALT development.- Lymphoid Tissue Inducer Cells in Intestinal Immunity.- Lymphocyte Homing to Gut Mucosa.- IGA Adaptation to the Presence of Commensal Bacteria in the Intestine.- Intestinal IgA Synthesis. A Primitive From of Adaptive Immunity that Regulates Microbial Communitities in the Gut.- B Cell Recruitment and Selection in Mouse GALT Germinal Centers in Response to Commensal Flora, in the Absence of BCR-Mediated Antigen Recognition.- Structural Insights Into Antibody-Mediated Mucosal Immunity.- Subject Index.

Автор: G. Jeanette Thorbecke; Vincent K. Tsiagbe
Название: The Biology of Germinal Centers in Lymphoid Tissue
ISBN: 3662131439 ISBN-13(EAN): 9783662131435
Издательство: Springer
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Описание: This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated.